DICYNONE TAB

Etamsylate primarily works by enhancing the stability of blood clots and promoting platelet aggregation. It selectively blocks the excessive breakdown of blood clots, a process known as fibrinolysis, which is often triggered by various factors such as injuries or certain medical conditions. By inhibiting the activation of plasminogen to plasmin, a key enzyme in fibrinolysis, Etamsylate helps maintain the integrity of blood clots, thereby reducing the risk of excessive bleeding. This mechanism is particularly crucial in situations where the body's natural clotting processes are compromised or when there is a heightened risk of bleeding due to trauma or surgical procedures.

Etamsylate

Antifibrinolytic agent

Tablet

The following are the uses of Etamsylate Tablet:

• Used for reducing excessive blood loss during menstruation (menorrhagia) by promoting blood clotting.
• Used for treating bleeding disorders like hemophilia, where it helps control bleeding episodes.
• Used for managing bleeding in the stomach and intestines, such as in ulcers or after surgery.
• Used for preventing and treating bleeding in the brain, often caused by injuries or certain medical conditions.
• Used for enhancing blood clotting in individuals with liver disorders, who may have impaired clotting ability.
• Used for reducing bleeding and speeding up wound healing after dental procedures or oral surgeries.
• Used for controlling bleeding in patients with certain blood disorders or those undergoing invasive procedures.
• Used for post-operative care to minimize bleeding and promote faster recovery.

In the case of an overdose of Etamsylate Tablets, the primary concern is gastrointestinal bleeding. Symptoms may include nausea, vomiting, and in severe cases, black or tarry stools. Prompt medical attention is required as excessive bleeding can lead to hypotension and shock. Treatment focuses on stabilizing the patient, and managing bleeding through fluid replacement and, if necessary, blood transfusions. It is crucial to seek medical help immediately if an overdose is suspected.

In the case of a missed dose of Etamsylate Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to proceed, as they may recommend adjusting your dosage or provide specific instructions for catching up on missed doses safely.

To take Etamsylate Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, either before or after meals, as directed by your healthcare professional.

Here are the conditions and situations when Etamsylate Tablet should not be taken:

• Should not be used in patients with a known allergy or hypersensitivity to Etamsylate or any of its excipients.
• Contraindicated in individuals with a history of bleeding disorders such as hemophilia or von Willebrand disease.
• Not recommended for patients with active bleeding from peptic ulcers or gastrointestinal bleeding.
• Should be avoided in patients with severe liver disease or impaired liver function.
• Contraindicated during active thrombosis or thromboembolic disorders.
• Not suitable for individuals with a history of allergic reactions to sulfonamides, as Etamsylate is a sulfa-based medication.
• Should not be used in patients with known or suspected blood disorders like sickle cell anemia or thalassemia.
• Contraindicated in patients with a history of renal calculi (kidney stones) or conditions that increase the risk of stone formation.

The side effects of Etamsylate Tablet may include:

• Skin rash or itching
• Gastrointestinal disturbances (e.g., nausea, vomiting, diarrhea)
• Headache
• Dizziness
• Fatigue
• Constipation
• Abdominal pain
• Allergic reactions (rarely)

Following are the precautions and warnings for Etamsylate Tablet:

• This medication is not recommended for individuals with known allergies to etamsylate or any other ingredients in the tablet.
• Patients with a history of gastrointestinal disorders should use it with caution, as it may cause gastrointestinal irritation.
• Etamsylate Tablet may affect blood clotting, so patients with bleeding disorders or those taking anticoagulant medications should be monitored closely.
• Patients with liver disease should exercise caution and have their liver function monitored regularly.
• Elderly patients may be more sensitive to the side effects, so dosage adjustments might be necessary.
• This medication should be used with caution in pregnant and breastfeeding women, only if the potential benefits outweigh the risks.
• If you experience any unusual bleeding or bruising while on Etamsylate Tablet, seek medical attention immediately.

Following are the drug interactions for Etamsylate Tablet:

• Concomitant use with anticoagulant medications, such as heparin or warfarin, should be closely monitored as Etamsylate may enhance their effects, potentially leading to excessive bleeding.
• Etamsylate can interact with non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin, ibuprofen, or naproxen, increasing the risk of gastrointestinal bleeding.
• It may reduce the absorption of iron supplements, so separate administration of these medications by at least 2 hours is recommended.
• The efficacy of Etamsylate can be reduced by concurrent use of barbiturates, which may induce the metabolism of Etamsylate.
• When used with other drugs affecting blood clotting, such as clopidogrel or enoxaparin, close monitoring is necessary to prevent excessive bleeding.
• Etamsylate may interact with certain antibiotics, particularly quinolones, potentially increasing the risk of bleeding.
• Caution is advised when combining Etamsylate with herbal supplements like garlic, ginkgo biloba, or ginseng, as these may also affect blood clotting.

Following are the food interactions for Etamsylate Tablet:

• Consuming alcohol is generally not recommended as it may increase the risk of bleeding and interfere with the medication's effectiveness.
• Grapefruit and grapefruit juice should be avoided as they can inhibit the metabolism of Etamsylate, potentially leading to increased drug levels in the body.
• High-salt foods should be limited as Etamsylate is used to reduce blood clotting, and excessive salt intake may counteract its effects.
• Foods rich in vitamin K, like leafy green vegetables, should be consumed in moderation as vitamin K promotes blood clotting, which could reduce the effectiveness of Etamsylate.
• Avoid eating large amounts of cranberries or drinking cranberry juice as they may increase the risk of bleeding when combined with Etamsylate.
• Garlic and ginger, known for their blood-thinning properties, should be used in moderation to prevent excessive bleeding risks.
• Fish oil supplements or fatty fish rich in omega-3 fatty acids may enhance the blood-thinning effects of Etamsylate, so monitor your intake.
• Consult your healthcare provider for specific dietary guidelines, especially if you have a history of bleeding disorders or are taking other medications.

Etamsylate Tablets should be stored in a secure and dry location, preferably in a medicine cabinet or a designated storage area, away from direct sunlight, moisture, and heat. It is crucial to keep the tablets in their original packaging or container, ensuring the label is intact for easy identification. Avoid transferring the tablets to other containers to prevent mix-ups with other medications. Always check the expiration date, and do not use the medication if it is past its expiry. When disposing of unused or expired Etamsylate Tablets, do not throw them in the trash or flush them down the toilet. Contact your pharmacist or local waste management authorities for guidance on safe disposal methods to minimize environmental impact. Keep the tablets out of children's reach to prevent accidental consumption, and ensure they are stored in a child-resistant container if available.

Following are the quick tips for Etamsylate Tablet:

• Take the tablet as directed by your doctor, typically 1-3 times a day.
• Consume the tablet with a full glass of water to aid in swallowing.
• It can be taken with or without food, but taking it with food may reduce the risk of stomach upset.
• Avoid crushing or chewing the tablet; swallow it whole for best results.
• If you experience nausea, taking the tablet with a light snack may help.
• Store the medication in a cool, dry place, away from direct sunlight and moisture.
• Do not share your medication with others, even if they have similar symptoms.