Dilzem (30mg) 30 Tablets

Diltiazem, the active ingredient in the 30mg tablet, primarily exerts its therapeutic effects through calcium channel blockade. It selectively inhibits L-type calcium channels in cardiac and vascular smooth muscle cells. By binding to these channels, diltiazem prevents calcium ions from entering these cells, leading to a reduction in intracellular calcium levels. This decrease in calcium concentration results in a relaxation of vascular smooth muscle, causing peripheral vasodilation, which in turn lowers blood pressure. Additionally, diltiazem's inhibition of calcium influx into cardiac myocytes slows electrical conduction through the atrioventricular (AV) node, leading to a decrease in heart rate and reduced myocardial contractility, contributing to its therapeutic actions.

Diltiazem 30mg

Calcium channel blocker.

Tablet

The following are the uses of Diltiazem 30mg Tablet:

• Used for managing high blood pressure, effectively lowering and controlling hypertension.
• Used for treating and preventing chest pain (angina), providing relief and reducing the frequency of angina episodes.
• Used for stabilizing irregular heart rhythms, helping to regulate and normalize heartbeats.
• Used for improving blood flow and circulation, particularly in conditions like Raynaud's phenomenon.
• Used for managing specific heart conditions like hypertrophic cardiomyopathy, reducing the risk of complications.
• Used for preventing blood vessel spasms, especially in conditions related to blood vessel constriction.
• Used for supporting overall cardiovascular health, promoting a healthy heart and vascular system.
• Used for certain arrhythmias, helping to restore a regular heart rhythm.

In the case of an overdose of Diltiazem 30mg Tablets, it is important to recognize the potential severity of the situation. Symptoms may include dizziness, extreme fatigue, and an irregular heartbeat. If you suspect an overdose, seek medical advice promptly. Treatment may involve supportive care, monitoring vital signs, and managing symptoms until the medication is cleared from the body. Quick action can help mitigate the risks associated with this medication.

In the case of a missed dose of Diltiazem 30mg Tablet, it is important to take the medication as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. However, do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance, as they may advise you to restart the medication or adjust the dosage accordingly to ensure the treatment remains effective.

To take Diltiazem 30mg tablets, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, typically taken once or twice a day, with or without food, as directed by your doctor.

Following are the conditions when Diltiazem 30mg Tablet should not be used:

• Must not be taken by individuals with a known allergy to Diltiazem or other similar calcium channel blockers.
• Contraindicated in patients with severe low blood pressure (hypotension).
• Not suitable for patients with a heart condition called 'AV block' or sick sinus syndrome unless a pacemaker is present.
• Should not be used in individuals with severe heart failure or unstable angina.
• Avoid in patients with a history of heart attack in the last 7 days.
• Do not use in patients with liver disease or impaired liver function.
• Contraindicated in patients with a rare inherited muscle disorder called myasthenia gravis.

The side effects of Diltiazem 30mg Tablet may include:

• Dizziness or lightheadedness
• Fatigue or weakness
• Headache
• Nausea and vomiting
• Constipation or diarrhea
• Slow heart rate (bradycardia)
• Swelling in the legs or ankles (peripheral edema)
• Skin rashes or flushing

Following are the precautions and warnings for Diltiazem 30mg Tablet:

• Avoid using this medication if you have a known allergy to Diltiazem or any calcium channel blockers.
• Patients with liver or kidney disease should use this medication with caution as it may require dosage adjustments.
• Diltiazem can cause dizziness or lightheadedness; avoid activities that require alertness until you know how the medication affects you.
• Elderly patients may be more sensitive to the effects and side effects of this medication, so close monitoring is necessary.
• Inform your doctor if you have any heart-related conditions, as Diltiazem can affect heart rate and blood pressure.
• Do not abruptly stop taking this medication as it may lead to worsening of your condition; always consult your doctor for any changes.
• This medication may interact with other drugs, so inform your healthcare provider about all medications you are currently taking.

Following are the drug interactions for Diltiazem 30mg Tablet:

• Co-administration with beta-blockers can lead to enhanced bradycardia and hypotension.
• When combined with digoxin, diltiazem may increase digoxin levels, requiring careful monitoring of digoxin concentrations.
• The use of diltiazem with other calcium channel blockers can result in additive effects and increased risk of adverse events.
• It may interact with statins, potentially increasing the risk of muscle-related side effects, and monitoring for myopathy is advised.
• Diltiazem can increase the blood levels of certain antifungal medications, such as ketoconazole, requiring dosage adjustments.
• The effectiveness of antihypertensive medications, including ACE inhibitors and diuretics, may be enhanced by diltiazem.
• Caution is necessary when combining diltiazem with immunosuppressants, as it can increase their blood levels, necessitating dosage adjustments.

Following are the food interactions to consider with Diltiazem 30mg Tablet:

• Grapefruit and grapefruit juice should be consumed with caution as they may increase the levels of Diltiazem in the blood, potentially leading to an increased risk of side effects, especially related to blood pressure and heart rate.
• Alcohol may enhance the hypotensive effects of Diltiazem, causing excessive dizziness or lightheadedness. It is advisable to limit alcohol consumption while taking this medication.
• High-fat meals can slightly increase the absorption of Diltiazem, but this effect is generally not clinically significant. However, it's best to maintain a consistent diet pattern when taking this medication.
• Caffeine intake should be monitored as it may counteract the effects of Diltiazem on heart rate and blood pressure, potentially reducing the medication's efficacy.
• Foods rich in potassium, like bananas and oranges, should be consumed in moderation as Diltiazem can cause potassium levels to rise, potentially leading to hyperkalemia.
• Salt and sodium-rich foods may need to be reduced in the diet as Diltiazem can cause sodium retention, affecting blood pressure control.
• Avoid excessive consumption of licorice, as it may reduce the effectiveness of Diltiazem by inhibiting its metabolism.
• Always consult your healthcare provider for personalized advice on diet and medication interactions.

Diltiazem 30mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. The medication should be kept in its original container, tightly sealed, to maintain its integrity and prevent exposure to environmental factors. It is crucial not to store the tablets in the bathroom or near heat-emitting appliances, as temperature fluctuations can impact their effectiveness. When disposing of unused or expired tablets, avoid flushing them down the toilet or pouring them into drainage systems. Instead, consult a pharmacist or healthcare professional for guidance on appropriate disposal methods. Always keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Diltiazem 30mg Tablet:

• Take the tablet as directed by your doctor, typically 3 to 4 times a day.
• Consume the tablet with a full glass of water, preferably with or just after meals.
• Avoid crushing, breaking, or chewing the tablet; swallow it whole for effective absorption.
• Maintain a consistent dosing schedule to ensure stable blood levels of the medication.
• If you experience dizziness, lightheadedness, or headache, rise slowly from a sitting or lying position.
• Inform your doctor about all the medications you are taking to prevent potential drug interactions.
• Store the tablets at room temperature, away from moisture and direct sunlight.