DioPlus (10/160mg) 14 Tablets

Amlodipine is a medication that helps to dilate blood vessels and improve blood flow, and is hence used to treat hypertension and chest pain (angina). Valsartan is also a medication that helps to relax the blood vessels and reduce the workload on the heart, and is used to treat hypertension and congestive heart failure. When used in combination, amlodipine and valsartan help to reduce blood pressure by dilating the blood vessels and reducing the amount of blood the heart has to pump out. This reduces the risk of heart attacks and strokes.

Calcium Channel Blocker, Angiotensin Receptor Blocker

Unveiling its multifaceted uses and transformative applications as follows:

• Lowering of blood pressure
• Treatment of hypertension
• May improve survival in those with hypertension and left ventricular hypertrophy
• Reduction of angina attacks in those with coronary artery disease
• Reduction of myocardial infarction in those with coronary artery disease
• Prevention of progression of asymptomatic left ventricular dysfunction
• Treatment of hypertensive emergency and hypertension while stabilizing patients undergoing surgery
• Treatment of heart failure

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Amlodipine is a calcium channel blocker used to treat hypertension (elevated blood pressure).
• The recommended starting dose is 5-10 mg once daily.
• Valsartan is an angiotensin II receptor antagonist (sometimes called an ARB) and is used to treat high blood pressure.
• It is also used to decrease the risk of stroke in people who have had a stroke already.
• For adults, the typical starting dose is 80-160 mg by mouth once a day.

In the case of an overdose of amlodipine 10 mg and valsartan 160 mg, symptomatic treatment is necessary to ensure the patient's comfort and safety. This may entail monitoring vital signs, managing pain, and treating symptoms like respiratory distress with oxygen therapy. However, enhanced elimination techniques, such as dialysis, are rarely required for these specific medications. The specific treatment approach will depend on the patient's individual condition and the severity of the overdose. Regardless, it is advisable to seek immediate medical attention since it is the most adequate solution for a drug overdose. Seeking immediate medical attention for oneself or someone else if an overdose is suspected or if symptoms of a drug overdose are observed is crucial. Medical professionals have the necessary tools and resources to address these situations and their potential dangers effectively." with "In the case of an overdose of amlodipine 10 mg and valsartan 160 mg, symptomatic treatment is necessary to ensure the patient's comfort and safety. This may entail monitoring vital signs, managing pain, and treating symptoms like respiratory distress with oxygen therapy. However, enhanced elimination techniques, such as dialysis, are rarely required for these specific medications. The specific treatment approach will depend on the patient's individual condition and the severity of the overdose. Regardless, it is advisable to seek immediate medical attention since it is the most adequate solution for a drug overdose. Seeking immediate medical attention for oneself or someone else if an overdose is suspected or if symptoms of a drug overdose are observed is crucial. Medical professionals have the necessary tools and resources to address these situations and their potential dangers effectively.

If you have missed a dose of amlodipine and valsartan, here are the steps you should take:

Amlodipine and valsartan are both taken orally, typically once daily whether with or without food. The dosage depends on the severity of your condition and response to treatment, as well as considerations made by your personal doctor. It is important to take these regularly as prescribed because they are most effective over time, and should not be stopped simply because you feel well. In fact, you must take these medications regularly as it treats a chronic condition aiming to prevent heart attacks or stroke. Should you have any questions or concerns about taking these medications, be sure to consult with your doctor or pharmacist.

Discerning instances where this medication may not be appropriate:

• If you are allergic to either of the active ingredients (amlodipine or valsartan) or any of the inactive tablet ingredients.
• If you have certain heart problems such as aortic stenosis or muscular dystrophy.
• If you have liver problems or decreased liver function or an upcoming surgery or procedure in which you will receive anesthesia.
• If you are pregnant, plan to become pregnant, or are breastfeeding.
• If you have had a serious allergic reaction to similar medications in the past.
• It is important to provide your doctor with accurate and detailed information about your health history and update them on any

Unraveling the side effects lurking behind this medications are as follows:

• Dizziness
• Headache
• Tiredness
• Abdominal pain
• Constipation
• Nausea

Amlodipine Rare side effects

• Allergic reactions such as hives
• Swelling of the lips, face, throat, and tongue
• Itching
• Difficulty breathing

Valsartan Common side effects

• Dizziness
• Fatigue
• Weakness
• Nausea
• Coughing
• Difficulty breathing
• Swelling of the lips, tongue, and face

Valsartan serious side effects requiring immediate medical attention (rare cases)

• Sudden and rapid weight gain
• Severe headaches
• Unexplained abdominal or leg pain
• Valsartan may cause fetal harm when administered to a pregnant woman.

Here are the essential warnings and precautions for the use of the medication:

• Patients with sodium or volume depletion, idiopathic or hereditary angioedema, biliary obstructive disorders, or primary hyperaldosteronism should use this medication with caution. It should also be used carefully in patients with severe obstructive coronary artery disease, severe congestive heart failure (CHF), recent myocardial infarction (MI), mitral or aortic stenosis, hypertrophic cardiomyopathy with outflow tract obstruction, and diabetes mellitus (DM).
• Special attention is needed for patients undergoing surgery or dialysis.
• The medication should be used cautiously in those with renal conditions, such as chronic kidney disease or unilateral/bilateral renal artery stenosis, as well as in patients with mild to moderate hepatic impairment.
• The safety of the medication during lactation has not been well established, so it should only be used if advised by a healthcare provider.

Drug interactions with Amlodipine , Valsartan combination include:

• NSAIDs (may reduce antihypertensive effect)
• Potassium-sparing diuretics (risk of hyperkalemia)
• Lithium (increased risk of lithium toxicity)
• Rifampin (decreases amlodipine levels)
• CYP3A4 inhibitors (e.g., ketoconazole) (increases amlodipine levels)
• ACE inhibitors (additive hypotensive effects)
• Other antihypertensives (additive hypotensive effects)
• Grapefruit juice (increases amlodipine levels)
• Diuretics (may enhance antihypertensive effects)

The food interactions that should be considered while using Amlodipine and Valsartan are:

• High-sodium foods can reduce the effectiveness of the medication. A low-sodium diet is recommended.
• Avoid potassium-rich foods and excessive potassium supplements.
• Grapefruit juice may increase side effects by affecting the calcium channel blocker component. It’s best to avoid or limit grapefruit juice.
• Alcohol can amplify the medication’s effects, leading to dizziness or fainting. Limiting alcohol is advised.
• High-fat meals have no direct interaction, but a balanced diet supports overall health.

Amlodipine and valsartan are important medications that are used to treat high blood pressure and chest pain, also known as angina. As with all medications, there are important storage instructions that will ensure the drugs' effectiveness. Amlodipine 10 mg tablets should be stored at room temperature between 59°F and 86°F, while valsartan falls within the same storage guidelines, also being stored between 59°F and 86°F. These temperatures ensure the chemical composition of the drugs remains intact and effective for the treatment of high blood pressure. It is also vital that these medications be stored in a secure location, free from the reach of children and pets. Please let me know if you have any other questions about storage instructions or the uses of either medication.