DMSO CREAM

Dimethyl Sulfoxide (DMSO) cream exerts its therapeutic effects primarily through its ability to penetrate the skin and act as a carrier for other substances. The unique molecular structure of DMSO allows it to easily pass through cell membranes, including the skin barrier. Once absorbed, DMSO enhances the penetration and delivery of other active ingredients present in the cream to underlying tissues. It achieves this by disrupting the lipid bilayer of cell membranes, making them more permeable. This increased permeability facilitates the transport of therapeutic agents into the target area, potentially improving their effectiveness. Additionally, DMSO itself possesses anti-inflammatory and antioxidant properties, which may contribute to its overall mechanism of action by reducing inflammation and oxidative stress in the affected tissues.

Topical anti-inflammatory

Cream

The following are the uses of Dimethyl Sulfoxide Cream:

• Used for treating skin conditions like psoriasis, atopic dermatitis, and scleroderma.
• Used for reducing inflammation and soothing skin irritation.
• Used for promoting wound healing and managing burns.
• Used for moisturizing and softening dry, rough skin.
• Used for managing symptoms of arthritis and joint pain.
• Used for supporting skin health during chemotherapy.
• Used for enhancing the penetration of other topical medications.

In the case of an overdose of Dimethyl Sulfoxide Cream, it is important to act swiftly. Symptoms may include skin irritation, redness, or a burning sensation at the application site. If ingested, nausea, vomiting, and abdominal pain could occur. In such instances, promptly contact a healthcare professional or a poison control center for guidance. They will provide specific instructions to manage the overdose, which may involve supportive care and symptomatic treatment.

In the case of a missed dose of Dimethyl Sulfoxide Cream, it is generally recommended to apply the cream as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra cream to make up for the missed dose, as this may increase the risk of skin irritation. If you frequently miss doses, it's advisable to set reminders or use a medication tracking app to help you stay on track with your treatment plan.

To apply Dimethyl Sulfoxide Cream, clean and dry the affected area, then gently massage a thin layer of the cream onto the skin, ensuring complete coverage, and allow it to absorb, typically two to three times a day or as directed by your healthcare provider.

Following are the conditions/situations when Dimethyl Sulfoxide Cream should not be applied:

• Must not be used on open wounds, deep cuts, or severe burns without medical supervision.
• Avoid using it on areas with severe skin infections or abscesses.
• Not suitable for individuals with known allergies to dimethyl sulfoxide or any of the cream's components.
• Should not be applied to the eyes or mucous membranes.
• Avoid using it on skin areas with active dermatitis or severe skin inflammation.
• Discontinue use if it causes severe skin irritation or an allergic reaction.
• Do not use if the cream shows signs of discoloration or contamination.
• Keep out of reach of children to prevent accidental ingestion.

The side effects of Dimethyl Sulfoxide Cream may include:

• Skin irritation or redness at the application site
• Itching or rash
• Dryness or scaling of the skin
• Burning or stinging sensation
• Swelling or inflammation
• Allergic reactions (such as hives, difficulty breathing, or swelling of the face/lips/tongue)
• Increased sensitivity to sunlight

Following are the precautions and warnings for Dimethyl Sulfoxide Cream:

• Avoid contact with eyes and mucous membranes. In case of accidental contact, rinse thoroughly with water.
• Not recommended for use on open wounds, broken skin, or severe skin conditions.
• Discontinue use if irritation, redness, or any adverse reaction occurs and consult a healthcare professional.
• Keep out of reach of children. Store in a cool, dry place, away from direct sunlight.
• Do not use if the seal is broken or the cream appears discolored or contaminated.
• For external use only. Do not ingest or apply to areas other than the intended treatment area.
• Consult a healthcare provider if you have any underlying medical conditions or are using other medications to ensure safe usage.

Following are the drug interactions for Dimethyl Sulfoxide Cream:

• It may increase skin absorption of other topical medications, leading to potential systemic effects.
• Dimethyl Sulfoxide can enhance the penetration of other drugs through the skin, increasing their effectiveness and potential side effects.
• Avoid using with other topical agents, as it may alter their absorption and effectiveness.
• When combined with certain medications, it may cause increased local skin reactions.
• May interact with drugs that are metabolized by the liver, potentially affecting their efficacy.
• Use with caution in patients on anticoagulant therapy, as it may enhance the effect of these drugs.
• Could potentially affect the metabolism of oral medications due to its impact on the liver.

Following are the food interactions to consider with Dimethyl Sulfoxide Cream:

• Grapefruit and its juice consumption should be avoided as it may interfere with the medication's metabolism, potentially leading to increased levels in the body.
• Alcoholic beverages might increase skin sensitivity and dryness, so it's best to limit or avoid alcohol during treatment.
• Certain spicy foods can exacerbate skin irritation and redness, especially if the skin is already sensitive or inflamed.
• Dairy products and high-fat meals may not directly interact with the medication, but maintaining a balanced diet is beneficial for overall skin health.
• Avoid excessive caffeine intake as it can dehydrate the skin, making it more susceptible to irritation.
• Staying hydrated by drinking plenty of water is essential to support skin health and minimize potential side effects.
• Avoid citrus fruits and juices as they can cause a stinging sensation and irritation when applied to the skin after using Dimethyl Sulfoxide Cream.
• Consult your healthcare provider for personalized advice on dietary considerations during treatment.

Dimethyl Sulfoxide Cream should be stored in a cool and dry environment, preferably at room temperature, ensuring protection from direct sunlight and moisture. The cream container should be tightly sealed to maintain its integrity and prevent contamination. Avoid exposing the cream to extreme temperatures, including heat sources like radiators or stoves, as this can impact its effectiveness. Dispose of any unused or expired cream responsibly; do not pour it down the drain or flush it in the toilet. Consult your pharmacist or healthcare professional for guidance on proper disposal methods. Keep the cream securely stored away from children to prevent accidental contact or ingestion.

Following are the quick tips for Dimethyl Sulfoxide Cream:

• Apply a thin layer of the cream to the affected area as directed by your doctor.
• Wash your hands before and after application to maintain hygiene.
• Gently rub the cream into the skin until it is fully absorbed.
• Avoid applying the cream to broken or irritated skin.
• Do not cover the treated area with bandages or tight clothing.
• Store the cream at room temperature, away from direct sunlight and moisture.
• Consult your doctor if you experience any skin irritation or allergic reactions.