Dolor (100mg/5ml) 60ml Suspension

Mefenamic acid, a nonsteroidal anti-inflammatory drug (NSAID), exerts its mechanism of action primarily through the inhibition of cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2. These enzymes play a crucial role in the synthesis of prostaglandins, which are mediators of inflammation and pain. By blocking the action of COX enzymes, mefenamic acid reduces the production of prostaglandins, thereby alleviating pain and inflammation. This inhibition of prostaglandin synthesis is the key to its therapeutic effects. Mefenamic acid is particularly effective in reducing inflammation, as it can decrease the production of inflammatory mediators at the site of injury or inflammation, leading to symptomatic relief.

Nonsteroidal anti-inflammatory drug (NSAID)

Suspension

The following are the uses of Mefenamic Acid 100mg Syrup/Suspension:

• Used for relieving mild to moderate pain, such as headaches, toothaches, and menstrual cramps.
• Used for reducing fever and inflammation caused by various conditions.
• Used to treat short-term pain and inflammation after minor surgeries or injuries.
• Effective for managing pain and discomfort associated with arthritis and musculoskeletal disorders.
• Helps alleviate discomfort and inflammation in the throat due to conditions like tonsillitis.
• Used for easing pain and reducing inflammation in conditions like osteoarthritis.
• Provides relief from pain and inflammation in the throat and mouth, including sore throat and mouth ulcers.
• Can be utilized for managing pain and inflammation in the short term during recovery from specific medical procedures.

Follow these dosage instructions:

• Take as per doctor's Prescription.
• Take one tablespoon of the syrup daily as your doctor suggests.
• Your doctor will determine the treatment length based on your symptom severity.

In the case of an overdose of Mefenamic Acid 100mg Syrup/Suspension, it is important to recognize the potential severity of this situation. Common symptoms may include nausea, vomiting, dizziness, and in more serious cases, kidney problems or gastrointestinal bleeding. Prompt medical intervention is necessary, and healthcare professionals should be contacted immediately for guidance and appropriate treatment options. Timely action can help mitigate the risks associated with an overdose.

In the case of a missed dose of Mefenamic Acid 100mg Syrup/Suspension, it is recommended to take the missed dose as soon as you remember, provided it is not too close to the time of your next scheduled dose. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. It is important to maintain a consistent medication routine for the best therapeutic effect.

To take Mefenamic Acid 100mg Syrup/Suspension, shake the bottle well, measure the prescribed dose with a measuring cup or oral syringe, and administer it orally, following the dosage instructions provided by your healthcare professional, typically taken with or after food as directed.

Following are the conditions/situations when Mefenamic Acid 100mg Syrup/Suspension should not be used:

• Should not be used in individuals with a known allergy or hypersensitivity to Mefenamic Acid or other non-steroidal anti-inflammatory drugs (NSAIDs).
• Contraindicated in patients with a history of asthma, severe bronchospasm, or allergic reactions triggered by aspirin or other NSAIDs.
• Not suitable for individuals with active gastrointestinal bleeding or a history of recurrent gastrointestinal bleeding.
• Should not be used in patients with severe heart failure or conditions that may lead to heart failure.
• Contraindicated in patients with severe kidney impairment or those at risk of renal failure.
• Not recommended for individuals who have recently undergone coronary artery bypass graft (CABG) surgery.
• Should be avoided in patients with a history of ulcerative colitis or Crohn's disease.
• Not suitable for individuals with bleeding disorders or those on anticoagulant therapy.
• Should not be used during the last trimester of pregnancy.

The side effects of using Mefenamic Acid 100mg Syrup/Suspension may include:

• Stomach upset or indigestion
• Nausea or vomiting
• Diarrhea or constipation
• Abdominal pain or cramps
• Headache or dizziness
• Rash or itching
• Increased risk of bleeding or bruising
• Fluid retention or swelling
• Elevated blood pressure
• Drowsiness or tiredness
• Risk of gastrointestinal ulcers or bleeding with prolonged use
• Allergic reactions such as swelling of the face or throat
• Kidney problems with long-term use

Following are the precautions and warnings for Mefenamic Acid 100mg Syrup/Suspension:

• Avoid using Mefenamic Acid if you have a known allergy to any non-steroidal anti-inflammatory drugs (NSAIDs) or any of the syrup's components.
• This medication should be used with caution in patients with a history of gastrointestinal bleeding, ulcers, or other gastrointestinal disorders. It may increase the risk of bleeding.
• Mefenamic Acid may cause an increased risk of cardiovascular events such as heart attack or stroke. Patients with cardiovascular disease or risk factors should use it with caution.
• It is recommended to monitor blood pressure regularly during treatment, especially in patients with hypertension.
• Patients with kidney or liver impairment should exercise caution and consult a healthcare provider before use, as dosage adjustments may be necessary.
• Mefenamic Acid should be avoided or used with extreme caution in the elderly, as they may be more susceptible to its side effects.
• Do not take this medication during the last 3 months of pregnancy unless absolutely necessary, and always consult a healthcare professional.

Following are the drug interactions for Mefenamic Acid 100mg Syrup/Suspension:

• May decrease the effectiveness of oral contraceptives, requiring additional contraceptive measures.
• Increased risk of bleeding when taken with anticoagulants like warfarin or antiplatelet drugs.
• Potentially increases plasma levels of lithium, requiring monitoring of lithium levels.
• Can reduce the renal clearance of methotrexate, leading to increased toxicity.
• Mefenamic acid may decrease the diuretic and antihypertensive effects of loop diuretics and angiotensin-converting enzyme (ACE) inhibitors.
• When used with other nonsteroidal anti-inflammatory drugs (NSAIDs), there is an increased risk of gastrointestinal bleeding and renal toxicity.
• Probenecid may increase the plasma concentration of mefenamic acid, possibly requiring a dosage adjustment.

Following are the food interactions for Mefenamic Acid 100mg Syrup/Suspension:

• Avoid alcohol consumption as it may increase the risk of gastrointestinal bleeding and liver toxicity.
• Grapefruit and grapefruit juice should be consumed with caution as they may interfere with the metabolism of Mefenamic Acid, potentially leading to increased drug levels in the body.
• High-fat meals may slightly delay the absorption of Mefenamic Acid but are generally well-tolerated.
• Dairy products like milk and cheese can be consumed, but if you have lactose intolerance, consider alternatives to avoid digestive discomfort.
• Avoid excessive caffeine intake as it may increase the risk of nervousness, insomnia, and heart palpitations.
• Spicy foods may irritate the stomach, especially if you have a history of gastrointestinal issues.
• Maintain a balanced diet rich in fruits, vegetables, and whole grains to support overall health while taking this medication.
• Stay hydrated by drinking adequate water to prevent dehydration, especially if you experience diarrhea as a side effect.

Mefenamic Acid 100mg Syrup/Suspension should be stored in a controlled environment, maintaining a cool temperature between 15-25°C (59-77°F) and protected from direct sunlight and moisture. Keep the medication in its original container, tightly sealed, to maintain its integrity and prevent contamination. Ensure you regularly check the expiration date, and if the syrup has passed its expiry, do not use it and dispose of it responsibly. Avoid pouring it down the drain or flushing it; instead, consult healthcare professionals for safe disposal methods. Always keep medications secure and out of children's reach to prevent accidental consumption.

No

Following are the quick tips for Mefenamic Acid 100mg Syrup/Suspension:

• Consult a doctor for prescription and dosage instructions.
• Administer the syrup as directed by your healthcare professional.
• Ensure you shake the bottle vigorously before each use for proper mixing.
• Consume the syrup with water; avoid tea, coffee, or dairy for better absorption.
• Maintain a consistent dosing schedule for maximum effectiveness.
• For stomach discomfort, consider taking it with food or post-meal.
• Store the medication safely, away from children's reach.