DOLORUB GEL 25G

Diclofenac, when combined with Linseed Oil Gel, forms a topical preparation that delivers the active ingredient, diclofenac, to the skin. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the production of prostaglandins, which are chemicals responsible for pain and inflammation. It does this by blocking cyclooxygenase (COX) enzymes, primarily COX-2, which are involved in the synthesis of prostaglandins. By reducing the production of prostaglandins, diclofenac helps to alleviate pain, decrease inflammation, and reduce fever. The gel formulation allows for localized application, enabling the drug to penetrate the skin and target the affected area directly, providing relief from musculoskeletal pain and inflammation.

Diclofenac, Methyl Salicylate, Menthol and Linseed oil

Non-steroidal anti-inflammatory drug (NSAID)

gel

The following are the uses of Diclofenac, Linseed Oil Gel:

• Used for relieving joint and muscle pain, including back pain, sprains, strains, and sports injuries.
• Used for reducing inflammation and swelling in affected areas.
• Used for managing pain and stiffness associated with arthritis.
• Used for providing temporary relief from minor aches and pains.
• Used for improving mobility and flexibility in painful joints and muscles.
• Used for treating soft tissue injuries and certain forms of tendonitis.
• Used for soothing discomfort and promoting healing in affected body parts.
• Used for offering targeted pain relief when applied topically to the skin.

In the case of an overdose of Diclofenac and Linseed Oil Gel, the severity of symptoms can vary. Gastrointestinal issues such as nausea, vomiting, and abdominal pain may occur. Additionally, individuals may experience headaches, dizziness, and in severe cases, seizures or loss of consciousness. Prompt medical attention is necessary, and treatment may involve supportive care and managing symptoms to prevent further complications. It is crucial to seek medical advice for specific guidance.

In the case of a missed dose of Diclofenac, Linseed Oil Gel, it is generally recommended to apply the gel as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra gel to make up for the missed dose, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare professional for guidance on how to get back on track with your treatment plan.

To apply Diclofenac, Linseed Oil Gel, gently massage a small amount of the gel onto the affected area, typically 2-3 times a day or as directed by your healthcare professional, ensuring that you clean and dry the skin before each application.

Following are the conditions/situations when Diclofenac and Linseed Oil Gel should not be used:

• Avoid using if you have a known allergy to Diclofenac, Aspirin, or any Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).
• Do not use if you have a history of asthma or severe allergic reactions triggered by Aspirin or other NSAIDs.
• Contraindicated in individuals with active or recent peptic ulcers, bleeding disorders, or severe heart failure.
• Should not be applied to areas of broken skin, infections, or open wounds.
• Not recommended for individuals with severe kidney or liver disease.
• Avoid using the gel if you are pregnant, especially during the last trimester, or breastfeeding without medical advice.
• Do not use the gel to treat children and adolescents under 18 years of age.
• Diclofenac gel should not be used on the face or near the eyes, nose, or mouth due to the risk of irritation.
• Do not cover the treated area with airtight dressings or bandages as it can increase the absorption of the medication.

The side effects of Diclofenac, Linseed Oil Gel may include:

• Skin redness or irritation at the application site
• Dry skin
• Burning or stinging sensation
• Itching
• Rash or hives
• Swelling of the face, lips, or throat (rare)
• Allergic reactions (such as difficulty breathing or severe skin reactions)
• Gastrointestinal discomfort (nausea, stomach pain)

Following are the precautions and warnings for Diclofenac, Linseed Oil Gel:

• Do not use the gel on broken or infected skin, or near the eyes, nose, mouth, or other sensitive areas.
• Wash your hands thoroughly after applying the gel to avoid accidental contact with these areas.
• Avoid using the gel on large areas of skin or under airtight dressings, as this may increase the risk of side effects.
• Individuals with a known allergy to diclofenac or linseed oil should not use this medication.
• If you have a history of asthma, bronchospasm, or other respiratory conditions, use with caution as it may trigger or worsen these conditions.
• Do not cover the treated area with bandages or apply heat, as this can increase the absorption of the medication and potentially cause adverse effects.
• Consult a healthcare professional if you are pregnant, planning to become pregnant, or breastfeeding before using this gel.

Following are the drug interactions for Diclofenac, Linseed Oil Gel:

• It may interact with other non-steroidal anti-inflammatory drugs (NSAIDs) and increase the risk of gastrointestinal bleeding and kidney problems.
• Anticoagulants like warfarin may have an enhanced effect when taken with Diclofenac, requiring close monitoring of blood clotting times.
• Lithium levels can be affected by Diclofenac, potentially leading to lithium toxicity.
• The diuretic effect of furosemide may be reduced when used with Diclofenac.
• ACE inhibitors and angiotensin receptor blockers may have reduced effectiveness when combined with Diclofenac.
• When taken with cyclosporine, Diclofenac may lead to increased cyclosporine levels and potential toxicity.
• The risk of gastrointestinal bleeding can increase when combined with selective serotonin reuptake inhibitors (SSRIs).
• Caution is advised when using Diclofenac with corticosteroids, as the risk of gastrointestinal side effects may be elevated.

Following are the food interactions for Diclofenac, Linseed Oil Gel:

• Alcohol consumption should be avoided or limited while using Diclofenac as it can increase the risk of gastrointestinal bleeding and liver damage.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of Diclofenac, potentially increasing its levels in the body and the risk of side effects.
• Fatty foods can affect the absorption of Diclofenac, especially when taken in oral form. It is recommended to avoid high-fat meals before or after taking the medication.
• Linseed Oil Gel may interact with foods containing high levels of omega-3 fatty acids, potentially increasing the risk of bleeding when taken in combination.
• Avoid excessive intake of vitamin E-rich foods or supplements as they can enhance the anticoagulant effect of Linseed Oil Gel.
• Certain vegetables like broccoli, Brussels sprouts, and cabbage contain compounds that can affect the metabolism of Diclofenac, potentially reducing its effectiveness.
• Avoid fish oil supplements or foods with high fish oil content as they may increase the risk of bleeding when combined with Diclofenac and Linseed Oil Gel.
• There is no significant interaction with dairy products, but it's best to follow healthcare advice regarding calcium-rich foods when taking Diclofenac.

Diclofenac, Linseed Oil Gel should be stored in a cool and dry place, preferably at room temperature, ensuring it is kept away from direct sunlight, heat, and moisture. It is crucial to store the gel in its original container, tightly sealed, to maintain its integrity and prevent contamination. When disposing of the gel, exercise caution and avoid flushing it down the toilet or pouring it into any drainage system. Instead, seek guidance from a pharmacist or healthcare professional regarding the appropriate disposal methods. Remember to keep the gel out of children's reach to prevent accidental contact or ingestion. Regularly check the expiry date on the packaging, and properly discard any expired or unused gel according to the recommended procedures.

Following are the quick tips for Diclofenac and Linseed Oil Gel:

• Apply a thin layer of the gel to the affected area as directed by your doctor or pharmacist.
• Wash your hands before and after applying the gel to avoid spreading the medication.
• Gently massage the gel into the skin until it is fully absorbed.
• Avoid applying the gel to broken or irritated skin.
• Do not cover the treated area with bandages or tight clothing to allow proper ventilation.
• If you experience skin irritation, stop using the gel and consult your healthcare provider.
• Store the gel at room temperature, away from direct sunlight and moisture.