DOSIK LIQUID 120ML

Haloperidol, a potent antipsychotic medication, exerts its effects primarily by blocking dopamine receptors in the brain, specifically the D2 receptors. This mechanism of action is central to its therapeutic effects in treating psychotic disorders. By binding to these receptors, haloperidol inhibits dopamine neurotransmission, which is believed to be crucial in managing symptoms associated with psychosis, such as hallucinations and delusions. The drug's selectivity for D2 receptors over other dopamine receptor subtypes contributes to its efficacy in symptom control while potentially reducing certain side effects associated with non-selective dopamine blockade. This targeted action on the dopaminergic system underlies haloperidol's clinical utility in the management of various psychiatric conditions requiring dopamine receptor antagonism.

Haloperidol

Antipsychotic

Solution

The following are the uses of Haloperidol Liquid:

• Used for managing symptoms of schizophrenia, helping patients control hallucinations and delusions.
• Used for treating severe behaviour problems in children with developmental disorders.
• Used for controlling episodes of sudden aggression, agitation, or violent behaviour.
• Used for reducing persistent feelings of anxiety and restlessness.
• Used for managing severe nausea and vomiting, especially in cancer patients.
• Used for supporting detoxification and managing severe withdrawal symptoms in alcohol or drug addiction.
• Used for treating severe tic disorders, helping to reduce the frequency and intensity of tics.
• Used for alleviating severe sleep disturbances, promoting more restful sleep.

In the case of an overdose of Haloperidol Liquid, the symptoms can vary depending on the amount ingested. Common signs include severe drowsiness, muscle stiffness, and difficulty breathing. Other potential effects are rapid heartbeat, low blood pressure, and seizures. Immediate medical intervention is necessary, where healthcare professionals may induce vomiting or perform gastric lavage to remove the excess medication. Prompt treatment can mitigate the risks and prevent severe complications.

In the case of a missed dose of Haloperidol Liquid, it is important to act promptly. If you remember within a few hours of the missed dose, administer the medication as soon as possible. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or asking someone to help you remember to take your medication on time.

To take Haloperidol Liquid, measure the prescribed dose using a measuring cup or oral syringe, then swallow the liquid directly or mix it with a small amount of water or juice, and consume it immediately, following the dosage instructions provided by your healthcare professional.

Following are the conditions/situations when Haloperidol Liquid should not be used:

• Must not be used in patients with a known allergy or hypersensitivity to Haloperidol or other similar antipsychotic medications.
• Contraindicated in patients with Parkinson's disease, as it can worsen symptoms.
• Should not be used in individuals with a history of blood clots or conditions that increase the risk of blood clots.
• Not suitable for patients with severe depression or those at risk of suicide.
• Avoid using in patients with severe liver or kidney impairment.
• Contraindicated in patients with a history of seizures or epilepsy.
• Should not be administered to patients with severe heart disease or an irregular heartbeat.
• Must be avoided in individuals with a suspected or confirmed brain tumor.
• Not recommended for elderly patients with dementia-related psychosis.
• Contraindicated during breastfeeding, as it can pass into breast milk.

The side effects of Haloperidol Liquid may include:

• Muscle stiffness or rigidity
• Tremors or shaking
• Drowsiness or sedation
• Restlessness or agitation
• Dizziness or lightheadedness
• Blurred vision
• Skin rashes or itching
• Constipation

Following are the precautions and warnings for Haloperidol Liquid:

• Not suitable for individuals with a known allergy to Haloperidol or related substances.
• Requires careful monitoring in patients with a history of cardiovascular diseases, as it may cause QT prolongation.
• Should be used with caution in patients with liver or kidney problems, as dosage adjustments might be necessary.
• Elderly patients may be more sensitive to the effects, hence, close supervision is advised.
• Avoid sudden discontinuation of the medication to prevent withdrawal symptoms.
• May cause drowsiness and dizziness, so patients should avoid driving or operating heavy machinery until fully alert.
• Consult a healthcare professional if you have a history of seizures, as Haloperidol may lower the seizure threshold.

Following are the drug interactions for Haloperidol Liquid:

• Concomitant use with other central nervous system depressants (e.g., benzodiazepines, opioids, or alcohol) can enhance respiratory depression and sedation.
• Antipsychotics like Haloperidol may antagonize the effects of Levodopa and other dopaminergic agents used in Parkinson's disease, potentially worsening motor symptoms.
• Haloperidol may increase the risk of cardiac arrhythmias when used with other medications that prolong the QT interval, such as certain antiarrhythmics or some antibiotics.
• The effectiveness of antihypertensive medications may be reduced by Haloperidol, requiring close monitoring of blood pressure.
• Anticonvulsant drug levels may be affected by Haloperidol, potentially reducing seizure control.
• Drugs that inhibit or induce CYP450 enzymes can alter the metabolism of Haloperidol, leading to either increased or decreased drug levels.
• Combining Haloperidol with other medications that lower the seizure threshold, such as certain antidepressants or stimulants, may increase the risk of seizures.

Following are the food interactions for Haloperidol Liquid:

• Grapefruit and grapefruit juice consumption should be avoided as they can alter the metabolism of Haloperidol, potentially leading to increased drug levels in the blood and a higher risk of side effects.
• Alcohol intake should be minimized or avoided as it can enhance the sedative effects of Haloperidol, causing excessive drowsiness and dizziness.
• Caffeine-rich beverages like coffee or energy drinks may counteract the calming effects of Haloperidol, potentially increasing anxiety or agitation.
• Fatty meals might slightly delay the absorption of Haloperidol, but this is generally not clinically significant.
• Consuming Haloperidol with food can reduce the risk of gastrointestinal discomfort and nausea, which are possible side effects.
• Avoid excessive salt intake, as Haloperidol can affect blood pressure regulation.
• Always follow healthcare provider's instructions regarding food and medication interactions.
• Certain herbal supplements may interact; consult a healthcare professional before use.

Haloperidol Liquid storage and disposal guidelines are crucial for maintaining its effectiveness and safety. Store the liquid in a cool, dry place, preferably at room temperature, away from sunlight and moisture. Keep the bottle tightly sealed to prevent contamination and ensure the medication remains sterile. Avoid extreme temperatures by not storing it in the bathroom or near heat sources. Regularly check the expiration date, and if the liquid becomes discolored or develops an unusual odor, do not use it and consult a pharmacist. Proper disposal is essential; do not pour it down the drain or flush it. Consult a healthcare professional or pharmacist for guidance on safe disposal methods to prevent environmental contamination. Keep the medication securely locked away from children and pets to prevent accidental ingestion.

Following are the quick tips for Haloperidol Liquid:

• Always measure the liquid accurately using the measuring cup or syringe provided.
• Store the liquid at room temperature, away from direct sunlight or extreme temperatures.
• Ensure the liquid is not frozen.
• Discard any unused or expired medication as per your pharmacist's guidelines.
• Do not mix with other liquids or substances.
• If you have difficulty swallowing, ask your pharmacist about alternative formulations.
• Inform your healthcare provider about all medications you are taking to avoid potential interactions.