Dotur (100mg) 10 Tablets

Doxofylline, the active ingredient in Doxofylline 100mg Tablets, primarily acts as a phosphodiesterase inhibitor. It selectively blocks specific phosphodiesterase enzymes, leading to increased levels of cyclic adenosine monophosphate (cAMP) in various cells, particularly in the respiratory system. This elevation of cAMP relaxes bronchial smooth muscles, resulting in bronchodilation and improved airflow to the lungs. Unlike other xanthine derivatives, Doxofylline has a unique structure that reduces its affinity for adenosine receptors, thereby minimizing potential side effects associated with these receptors, such as tachycardia or gastrointestinal discomfort.

Doxofylline 100mg

Bronchodilator, anti-inflammatory.

Tablet

The following are the uses of Doxofylline 100mg Tablet:

• Used for treating symptoms of chronic obstructive pulmonary disease (COPD) and asthma.
• Used to relax the airways and make breathing easier by opening up the air passages to the lungs.
• Used for relieving cough, wheezing, shortness of breath, and tightness in the chest.
• Used to prevent asthma attacks and manage flare-ups when they occur.
• Used as an alternative for patients who experience side effects with other similar medications.
• Used for long-term management of respiratory conditions to improve lung function.
• Used to reduce the need for other quick-relief inhalers over time.

In the case of an overdose of Doxofylline 100mg Tablets, it is important to recognize the signs and take appropriate action. Symptoms may include nausea, vomiting, rapid heartbeat, and dizziness. If you suspect an overdose, seek medical advice immediately. Promptly contact a healthcare professional or go to the nearest emergency room for assistance. Treatment options may include supportive care and monitoring, as well as managing any specific symptoms that arise due to the overdose.

In the case of a missed dose of Doxofylline 100mg Tablet, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. It is important to maintain a consistent dosing routine, but if you frequently miss doses, consult your healthcare provider for advice on how to effectively manage your medication schedule.

To take Doxofylline 100mg Tablet, swallow the tablet whole with a glass of water, preferably in the morning or as directed by your healthcare professional, and follow the prescribed dosage and duration as instructed by your doctor for the treatment of respiratory conditions.

Here are the conditions and situations when Doxofylline 100mg Tablet should not be used:

• Avoid using this medication if you have a known allergy to Doxofylline or any other xanthine derivatives.
• Do not take this medicine if you have a history of seizures or epilepsy.
• Contraindicated in patients with severe heart conditions, such as recent heart attack or severe heart rhythm disorders.
• Should not be used in individuals with severe liver impairment or active liver disease.
• Not recommended for individuals with gastric or duodenal ulcers.
• Avoid using this medication if you have narrow-angle glaucoma.
• Doxofylline is not suitable for people with severe hypertension (high blood pressure).
• Do not administer this medication to children under 12 years of age.

The side effects of Doxofylline 100mg Tablet may include:

• Nausea and vomiting
• Headache
• Restlessness or insomnia
• Increased heart rate (tachycardia)
• Skin rash or itching
• Dry mouth
• Gastrointestinal discomfort
• Dizziness

Following are the precautions and warnings for Doxofylline 100mg Tablet:

• This medication should be used with caution in patients with severe heart disease, as it may cause increased heart rate and palpitations.
• Patients with a history of stomach ulcers or gastrointestinal bleeding should exercise caution, as Doxofylline can irritate the stomach lining.
• Avoid alcohol consumption while taking this medication, as it may increase the risk of gastrointestinal side effects.
• Doxofylline may cause dizziness or lightheadedness; patients should rise slowly from a sitting or lying position to prevent falls.
• It is important to maintain adequate fluid intake while taking this medication to reduce the risk of dehydration.
• Patients with diabetes should monitor their blood sugar levels regularly, as Doxofylline may affect glucose metabolism.
• Do not exceed the prescribed dosage, as high doses may lead to seizures or other serious adverse effects.
• Consult your doctor if you have any pre-existing medical conditions or are taking other medications to ensure safe use.

Following are the drug interactions for Doxofylline 100mg Tablet:

• May increase theophylline levels, requiring dose adjustments.
• Can reduce the effectiveness of beta-blockers, particularly in patients with COPD.
• Antacids may decrease the absorption of Doxofylline, so separate administration by at least 2 hours.
• Doxofylline may decrease lithium clearance, potentially leading to increased lithium levels and toxicity.
• Concomitant use with ciprofloxacin may reduce the therapeutic effect of Doxofylline.
• Theophylline and other methylxanthines may increase the side effects of Doxofylline.
• Drug interactions with aminophylline can lead to increased adverse effects and toxicity.

Following are the food interactions to consider with Doxofylline 100mg Tablet:

• Grapefruit consumption should be limited or avoided as it can alter the drug's metabolism, potentially leading to increased side effects.
• Alcohol intake should be minimized as it may exacerbate certain side effects, particularly gastrointestinal discomfort.
• Avoid caffeine-rich foods and beverages as Doxofylline already contains a form of caffeine, and excess caffeine can cause nervousness, rapid heartbeat, and insomnia.
• Fatty meals might slow down the absorption of Doxofylline, potentially reducing its effectiveness.
• Avoid high-sodium foods as Doxofylline may increase sodium levels, and excessive sodium intake can be detrimental to those with heart or kidney issues.
• Dairy products, particularly milk, might interfere with the absorption of Doxofylline, leading to reduced effectiveness.
• Consuming foods high in sugar while taking Doxofylline can mask its bitter taste, but it's important to monitor overall sugar intake for health reasons.
• Always consult healthcare professionals for personalized advice, especially regarding dietary restrictions or modifications.

Doxofylline 100mg Tablets should be stored in a cool, dry area, ideally at room temperature, ensuring protection from direct sunlight and moisture. The original packaging should be tightly sealed to maintain its integrity and prevent contamination. Avoid placing the tablets in bathrooms or near heat-emitting appliances to prevent temperature-induced degradation. Regularly check the expiration date, and when disposing of unused or expired tablets, refrain from flushing them or pouring them down the drain. Instead, consult a pharmacist or healthcare professional for appropriate disposal methods, and always keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Doxofylline 100mg Tablet:

• Consult your doctor before use, especially if you have heart, liver, or kidney problems.
• Take the tablet as directed by your doctor; do not crush or chew it.
• Maintain a consistent dosing schedule to ensure optimal effectiveness.
• Stay hydrated and drink plenty of fluids while taking this medication.
• Avoid alcohol consumption as it may worsen side effects.
• Inform your doctor about all medications you are taking to prevent potential interactions.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.
• Do not share this medication with others, even with similar symptoms.