Dsun-T (2000 IU) 30 Capsules

Cholecalciferol, also known as vitamin D3, has a primary mechanism of action centered on its role in maintaining calcium homeostasis and promoting bone health. When ingested, cholecalciferol undergoes two hydroxylation reactions in the body. First, it is converted to 25-hydroxyvitamin D (calcifediol) primarily in the liver, and then further hydroxylated in the kidneys to form its active form, 1,25-dihydroxyvitamin D (calcitriol). Calcitriol acts as a hormone, binding to vitamin D receptors (VDR) in various target tissues. This binding activates the receptor, which then dimerizes and interacts with specific DNA sequences, regulating gene expression. The primary effect is to increase intestinal absorption of calcium and phosphorus, promoting their reabsorption and maintaining adequate serum levels. This, in turn, supports proper bone mineralization and overall skeletal health. Additionally, cholecalciferol may influence immune function, cell proliferation, and the modulation of various metabolic processes through its interaction with VDRs in different cell types.

Cholecalciferol 2,000iu

Vitamin D supplement

Capsule

The following are the uses of Cholecalciferol 2,000iu Capsule:

• Used for treating Vitamin D deficiency, ensuring healthy bones and muscles.
• Used to prevent osteoporosis, a condition where bones become weak and brittle.
• Used to support calcium absorption for optimal bone health.
• Used in cases of malabsorption syndromes to aid nutrient uptake.
• Used to maintain a healthy immune system and overall well-being.
• Used for individuals with limited sun exposure to meet Vitamin D needs.
• Used as a supplement during pregnancy for fetal bone development.
• Used to reduce the risk of fractures and falls, especially in older adults.

In the case of an overdose of Cholecalciferol 2,000 IU capsules, symptoms may include nausea, vomiting, constipation, loss of appetite, weakness, and kidney problems. Excessive vitamin D intake can lead to elevated calcium levels in the blood, causing potential harm to the kidneys and other organs. If an overdose is suspected, medical attention should be sought promptly, and treatment may involve monitoring and managing calcium and fluid levels in the body. It is crucial to follow the recommended dosage to prevent such adverse effects.

In the case of a missed dose of Cholecalciferol 2,000 IU Capsule, it is generally advised to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this may increase the risk of side effects. It is important to maintain consistency with vitamin D supplementation, so try to take the medication at the same time each day to establish a routine.

To take Cholecalciferol 2,000 IU capsules, simply swallow the capsule whole with a glass of water, preferably with a meal or as directed by your healthcare professional, ensuring it is taken consistently at the same time each day.

Following are the conditions or situations when Cholecalciferol 2,000iu Capsule should not be taken:

• Do not take if you have a known hypersensitivity or allergy to vitamin D or any of the excipients in the capsule formulation.
• Avoid if you have hypervitaminosis D (excessive vitamin D levels in the body).
• Do not exceed the recommended dosage, as it may lead to vitamin D toxicity.
• Not suitable for individuals with hypercalcemia (high blood calcium levels) or conditions causing hypercalcemia.
• Avoid if you have conditions like sarcoidosis, tuberculosis, or histoplasmosis, as these conditions may affect vitamin D metabolism.
• Do not take if you have kidney stones or a history of kidney disease.
• Not recommended for individuals with hyperparathyroidism (overactive parathyroid gland).
• Discontinue use if you experience symptoms of vitamin D overdose, such as nausea, vomiting, constipation, or confusion.

The side effects of Cholecalciferol 2,000 IU Capsule may include:

• Nausea and vomiting.
• Constipation or diarrhea.
• Loss of appetite.
• Dry mouth.
• Metallic taste.
• Fatigue and weakness.
• Muscle or joint pain.
• Excessive thirst.

Following are the precautions and warnings for Cholecalciferol 2,000 IU Capsule:

• Individuals with hypersensitivity or allergy to vitamin D or any of the capsule's components should not take this medication.
• Regular monitoring of vitamin D levels is recommended, especially in patients with a history of kidney stones or kidney disease.
• Those with a history of hypercalcemia or conditions that may lead to high calcium levels should exercise caution and consult a healthcare professional before use.
• Patients with impaired liver function should be monitored, as Cholecalciferol is metabolized in the liver.
• Avoid excessive use of the capsule, as it may lead to vitamin D toxicity, causing symptoms like nausea, vomiting, and constipation.
• Do not take other vitamin D supplements or calcium supplements without consulting a healthcare provider.
• Keep out of reach of children. Store in a cool, dry place, away from direct sunlight.
• Always consult a healthcare professional for proper dosage and duration of treatment.

Following are the drug interactions for Cholecalciferol 2,000 IU Capsule:

• Anticonvulsants like phenobarbital, phenytoin, and carbamazepine may reduce the effectiveness of Cholecalciferol by increasing its metabolism.
• Cholestyramine and colestipol can decrease the absorption of vitamin D (Cholecalciferol), leading to reduced effectiveness.
• Thiazide diuretics, when used long-term, may increase calcium levels in the blood, and concurrent use with Cholecalciferol can further elevate calcium levels.
• Taking Cholecalciferol with orlistat may decrease its absorption, requiring higher doses of the vitamin.
• Mineral oil, when used regularly, can decrease the absorption of fat-soluble vitamins like vitamin D, potentially reducing its effectiveness.
• Aluminum-containing antacids may decrease the absorption of Cholecalciferol, especially with long-term use.
• Corticosteroids (e.g., prednisone) may interfere with vitamin D metabolism, potentially requiring higher doses of Cholecalciferol to maintain adequate levels.

Following are the food interactions for Cholecalciferol 2,000 IU Capsule:

• Avoid excessive consumption of foods rich in Vitamin D, such as fatty fish (salmon, mackerel), egg yolks, and fortified dairy products, as it may lead to Vitamin D toxicity.
• Maintain a balanced diet with a variety of foods to ensure proper absorption and utilization of Vitamin D.
• Consuming Vitamin D supplements with a meal, preferably a fat-containing meal, can enhance its absorption in the body.
• Grapefruit juice should be consumed with caution as it may affect the metabolism of Vitamin D and increase its levels in the blood.
• Avoid excessive alcohol intake as it can interfere with Vitamin D metabolism and reduce calcium absorption, potentially leading to bone health issues.
• Caffeine-rich beverages may interfere with Vitamin D absorption, so consider limiting coffee and tea intake close to when you take the supplement.
• Certain medications, like steroids and anti-seizure drugs, can affect Vitamin D levels, so consult your healthcare provider for adjustments in dosage if needed.
• Always follow the dosage instructions provided by your healthcare professional to ensure safe and effective use of Vitamin D supplements.

Cholecalciferol 2,000iu Capsules should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial to keep the medication away from heat sources like radiators or stoves, as extreme temperatures can compromise its effectiveness. Regularly check the expiration date, and dispose of any unused or expired capsules responsibly, avoiding flushing or pouring them down the drain. Consult a pharmacist or healthcare professional for guidance on proper disposal methods. Additionally, ensure the medication is stored out of children's reach to prevent accidental consumption.

Following are the quick tips for Cholecalciferol 2,000iu Capsule:

• Take the capsule with a full glass of water for better absorption.
• Consume it with a meal containing healthy fats to enhance vitamin D absorption.
• Consider taking the capsule with a meal to reduce the risk of stomach upset.
• If you have trouble swallowing capsules, you can carefully open it and mix the content with a small amount of soft food.
• Do not crush or chew the capsule; swallow it whole.
• Maintain a consistent schedule for taking the capsule as directed by your healthcare provider.
• Store the capsules in a cool, dry place, away from direct sunlight and moisture.