DUETON CAPS 2'S

Ethinyloestradiol and ethisterone work together through a multi-step mechanism of action. Ethinyloestradiol is a synthetic estrogen functions by binding to estrogen receptors in target tissues, leading to the regulation of gene expression involved in the menstrual cycle and reproductive system. It promotes the development and maintenance of female reproductive tissues and secondary sexual characteristics. Ethisterone is a synthetic progestogen binds to progesterone receptors, regulating the menstrual cycle and preparing the endometrium for potential implantation of a fertilized egg. It also inhibits ovulation and maintains pregnancy by suppressing uterine contractions. The combination is commonly used in hormone replacement therapy and contraceptive formulations, providing both estrogenic and progestogenic effects to regulate reproductive functions.

Estrogen, Progestin

Ethinyloestradiol and Ethisterone are used for:

• Contraception
• Hormonal Replacement Therapy
• Regulation of Menstrual Cycles

Ethinyloestradiol/Ethisterone dosage for the indication of contraceptive, with ongoing use as per indication:

• Adults - 1 tablet daily for 21 days, followed by a 7-day break.
• Children - Not recommended.

Overdose may cause nausea, vomiting, or other hormonal side effects. Seek medical attention.

If you miss a dose, consume as soon as you remember. If it is close to the next feeding, skip the missed dose. Do not double up on doses.

Typically taken orally, either as a daily tablet or as prescribed by a healthcare provider. Follow the dosage schedule.

Ethinyloestradiol, Ethisterone should not be used if:

• Hypersensitivity
• History of thromboembolic disorders
• Liver disease
• Pregnancy

Possible side effects of Ethinyloestradiol and Ethisterone include:

• Nausea
• Headache
• Mood changes
• Weight gain
• Breast tenderness

The warnings and precautions associated with Ethinyloestradiol and Ethisterone are:

• Pregnancy.

The drug interactions with ethinyloestradiol and ethisterone include:

• Antibiotics (e.g., rifampin) – Can decrease the effectiveness of oral contraceptives.
• CYP3A4 Inducers (e.g., carbamazepine) – Can reduce hormone levels.

For Ethinyloestradiol and Ethisterone, food interactions that should be considered are:

• Taking with food may help improve absorption.
• Avoid taking with St. John's Wort as it may reduce effectiveness.

Ethinyloestradiol and Ethisterone should be stored at room temperature, away from light and moisture. Keep them in their original containers and out of reach of children. Dispose of expired or unused medications properly, following local disposal guidelines or using a drug take-back program.