Dulan (60mg)10 Capsules

Duloxetine is a medication that falls under the category of selective serotonin and norepinephrine reuptake inhibitors (SSNRIs). It is believed to help treat depression, anxiety, and neuropathic pain by increasing the amounts of serotonin and norepinephrine, which are neurotransmitters responsible for regulating mood and pain signals. This medication is usually prescribed to patients suffering from depression, anxiety, and neuropathic pain linked with diabetes or spinal cord injuries. It is typically used over a long period of time as a chronic daily treatment method. The recommended starting dose of duloxetine is 60 mg per day. This dosage can be adjusted by your medical professional to suit your specific needs, depending on your response to the medication. It is essential to adhere to the instructions given to you by your medical professional regarding dosage and use.

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Duloxetine

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Serotonin-Norepinephrine Reuptake Inhibitor (SNRI)

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Capsule

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Unveiling its multifaceted uses and transformative applications as follows:

• Treats depression
• Helps with anxiety attacks
• Decreases discomfort from pain caused by arthritis
• Useful for healing wounds after surgery (including plastic surgery)
• Treatment of stress incontinence (leaking of urine when you cough or sneeze) in women
• Chronic pain management for diabetic neuropathy (pain from nerve damage due to diabetes)
• Relief from pain due to shingles (herpes zoster)
• Migraine pain relief

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Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Depression- 60 mg once daily
• Anxiety- 60 mg once daily
• Diabetic neuropathy- 60 mg once daily
• Fibromyalgia- 60 mg once daily
• Pain- 60 mg once daily
• Osteoarthritis- 60 mg once daily
• Irritable bowel syndrome- 60 mg once daily
• Chronic Musculoskeletal Pain- 60 mg once daily

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Duloxetine is a medication that comes with the risk of an overdose if excessive amounts are consumed. Some of the symptoms of a duloxetine overdose may include nausea, vomiting, dizziness, loss of consciousness, and seizures. It's crucial to seek immediate medical attention if you or someone else has overdosed on duloxetine. Treatment for this overdose often involves pumping the stomach, specific medications, and general supportive care.

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If you have missed a dose of Duloxetine 60mg, it is important to take it as soon as possible. However, if it is almost time for your next dose, it is recommended to skip the missed dose and continue on your regular schedule. This is to avoid doubling up on doses, which can be harmful. If you have any questions or concerns, it is always best to consult with your physician for the best treatment plan for you.

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Duloxetine 60mg should be taken at the same time every day, preferably alongside or without food. It is important to follow the dosage and usage instructions provided by your doctor carefully, and to consult them if you have any questions or concerns about your treatment. Grapefruit products should be avoided as it can increase the risk of side effects. For adults, the recommended dose is 60-120mg per day, depending on the condition being treated. Any questions or concerns about the usage of the medication should be directed to your doctor or pharmacist for more information.

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Discerning instances where this medication may not be appropriate:

• Allergy to duloxetine or any of its ingredients is a contraindication.
• Past instances of mania, hypomania, or elevated, expansive, or irritated mood should be disclosed to your doctor.
• Don't take duloxetine if you have a history of seizures.
• Avoid duloxetine if you have bleeding issues or have had a stroke recently.
• If you have used MAO inhibitors in the last 14 days, duloxetine is not a safe option.

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Unraveling the side effects lurking behind this medications are as follows:

• Nausea
• Vomiting
• Loss of appetite
• Diarrhea
• Constipation
• Headache
• Insomnia
• Dizziness
• Increased anxiety or restlessness
• Irritability
• Anger
• Confusion
• Drowsiness
• Weakness
• Sweating

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Patients should be aware of the following precautions and warnings when considering this treatment:

• Avoid use in patients with a history of mania or bipolar disorder.
• Caution is necessary for individuals with a history of seizure disorders or conditions predisposing to seizures, such as brain damage.
• Not recommended for those with a history of suicide-related events or significant suicidal thoughts or behavior.
• Use cautiously in patients with increased intraocular pressure or those at risk of acute angle-closure glaucoma.
• Be aware of controlled hypertension or other cardiac diseases that may be compromised by increased heart rate or blood pressure.
• Caution is required for patients with known bleeding tendencies or susceptibility to hyponatraemia, such as those who are dehydrated or using diuretics.
• Consider the impact on individuals with impaired gastric motility, as well as smokers and heavy alcohol drinkers.
• Avoid abrupt discontinuation of the medication.
• Use with caution in patients with mild to moderate renal impairment.
• Special care is needed for children and elderly patients.
• Not recommended during pregnancy or lactation.

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Drug interactions with duloxetine include:

• Monoamine oxidase inhibitors (MAOIs) (e.g., phenelzine) (may cause severe serotonin syndrome- avoid concomitant use)
• Other antidepressants (e.g., SSRIs, SNRIs) (may increase the risk of serotonin syndrome- use with caution)
• CYP1A2 inhibitors (e.g., fluvoxamine) (may increase duloxetine levels- monitor for increased side effects)
• CYP2D6 inhibitors (e.g., paroxetine) (may increase duloxetine levels- monitor for increased side effects)
• Warfarin (may increase bleeding risk- monitor INR closely)
• Non-steroidal anti-inflammatory drugs (NSAIDs) (e.g., ibuprofen) (may increase bleeding risk- use cautiously)
• Alcohol (may enhance sedative effects and increase risk of adverse effects- use with caution)
• Benzodiazepines (e.g., diazepam) (may enhance sedative effects- monitor for increased sedation)
• Antihypertensive agents (e.g., ACE inhibitors) (may have additive effects on blood pressure- monitor blood pressure)
• Antiepileptic drugs (e.g., phenytoin) (may alter the metabolism of duloxetine- monitor for efficacy and side effects)

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Store duloxetine at room temperature, away from moisture, heat, and direct light. Keep it in its original packaging, tightly sealed, and out of reach of children and pets. Avoid storing it in the bathroom. For disposal, do not flush duloxetine down the toilet or pour it into drains unless instructed. Follow local disposal guidelines or use a drug take-back program to safely discard any unused or expired medication to prevent accidental exposure or misuse.

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