Duricef (250mg/5ml) 90ml Oral Suspension

Cefadroxil, an antibiotic belonging to the cephalosporin class, exerts its bactericidal effect by disrupting the synthesis of the bacterial cell wall. It specifically targets penicillin-binding proteins (PBPs), which are essential for cross-linking peptidoglycan strands in the cell wall. By binding to these PBPs, Cefadroxil interferes with the final stages of cell wall synthesis, leading to the weakening and eventual rupture of the bacterial cell wall, resulting in cell lysis and death. This mechanism of action is effective against a range of susceptible bacteria, including Streptococcus pyogenes, Staphylococcus aureus, and certain strains of Escherichia coli.

Cefadroxil 250mg

Oral cephalosporin antibiotic

Suspension

The following are the uses of Cefadroxil 250mg Syrup/Suspension:

• Used for treating bacterial infections, particularly in the respiratory tract, skin, and urinary tract.
• Used for managing infections caused by susceptible bacteria, such as streptococci and staphylococci.
• Used for relieving symptoms associated with bacterial infections, such as fever, inflammation, and pain.
• Used for preventing the spread of infection and improving patient comfort.
• Used for children and adults with mild to moderate infections.
• Used as an alternative for patients allergic to penicillin.
• Used for completing the full course as prescribed for effective treatment.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Upper Respiratory Tract Infections • 500 mg every 12 hours for 5-7 days
• Skin Infections • 500 mg daily for 7 days
• Bone & Joint Infections • 500 mg daily for 4 weeks
• Genitourinary Infections • 500 mg every 8 hours for 7-14 days
• Meningitis • 1000 mg once, then 500 mg every 12 hours for a week

In the case of an overdose of Cefadroxil 250mg Syrup/Suspension, it is important to recognize the potential symptoms. These may include nausea, vomiting, diarrhea, and abdominal pain. Prompt medical attention should be sought, and the patient should be monitored for any signs of an allergic reaction, such as a rash, itching, or difficulty breathing. Treatment may involve managing symptoms and ensuring the patient's vital signs remain stable until the excess medication is cleared from the system.

In the case of a missed dose of Cefadroxil 250mg Syrup/Suspension, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss several doses, contact your healthcare provider for advice on how to proceed with your treatment.

To administer Cefadroxil 250mg Syrup/Suspension, shake the bottle vigorously, measure the prescribed dose using an accurate measuring device like a medicine cup or syringe, and administer it orally, preferably with food, following the dosage instructions provided by your healthcare professional.

Following are the conditions/situations when Cefadroxil 250mg Syrup/Suspension should not be used:

• Avoid if allergic to Cefadroxil or any other cephalosporin antibiotics.
• Do not use if the patient has a history of severe allergic reactions to penicillin.
• Contraindicated in patients with a history of severe gastrointestinal diseases or conditions.
• Not suitable for individuals with kidney disease or significantly impaired kidney function.
• Avoid using in patients with a history of severe diarrhea or colitis caused by antibiotics.
• Should not be administered if the patient is already taking other medications that may interact adversely with Cefadroxil.
• Do not use in patients with a known sensitivity to any of the excipients in the suspension formulation.

The side effects of Cefadroxil 250mg Syrup/Suspension may include:

• Nausea and vomiting
• Diarrhea
• Abdominal pain or discomfort
• Skin rash or itching
• Dizziness
• Headache
• Vaginal itching or discharge
• Allergic reactions (such as hives, difficulty breathing, swelling of the face/lips/tongue)

Following are the precautions and warnings for Cefadroxil 250mg Syrup/Suspension:

• Do not use if you are allergic to Cefadroxil or any other cephalosporin antibiotics.
• This medication should be used with caution in patients with kidney disease, as dosage adjustments may be necessary.
• Cefadroxil may cause diarrhea; if it becomes severe or persistent, contact your doctor immediately.
• Avoid using this medication if you have a history of gastrointestinal diseases, especially colitis.
• Inform your doctor about any other medications you are taking to avoid potential drug interactions.
• Cefadroxil may cause false-positive results for certain urine glucose tests, so inform your doctor if you are undergoing such tests.
• Do not use this medication beyond the prescribed duration, as it may lead to bacterial resistance.
• Store the syrup/suspension in a cool, dry place, and discard any unused portion after the expiration date.

Following are the drug interactions for Cefadroxil 250mg Syrup/Suspension:

• Concomitant use with probenecid may decrease renal excretion of Cefadroxil, leading to increased plasma levels and a prolonged half-life.
• Warfarin and other anticoagulants may have an increased risk of bleeding due to Cefadroxil's potential to alter gut flora and vitamin K metabolism.
• Loop diuretics, such as furosemide, may enhance the risk of nephrotoxicity when combined with Cefadroxil.
• Aminoglycosides, such as gentamicin, may increase the risk of nephrotoxicity when co-administered with Cefadroxil.
• Oral contraceptives may have reduced effectiveness due to potential alterations in gut flora affecting estrogen absorption.

Following are the food interactions for Cefadroxil 250mg Syrup/Suspension:

• Cefadroxil should be taken with food to reduce the risk of gastrointestinal upset, as it can irritate the stomach lining.
• Avoid consuming large amounts of calcium-rich foods like dairy products immediately after taking the medication, as calcium can interfere with the absorption of Cefadroxil.
• Alcohol consumption is not recommended during the course of treatment, as it may increase the risk of side effects and stomach irritation.
• Grapefruit and grapefruit juice should be avoided as they can alter the effectiveness of Cefadroxil by affecting liver enzymes.
• Avoid highly acidic foods or beverages, such as citrus fruits or juices, as they may cause discomfort and potentially reduce the drug's absorption.
• Maintain a balanced diet to support overall health and ensure the medication's effectiveness.
• Consult your healthcare provider for specific dietary recommendations and any necessary adjustments during the treatment period.

Cefadroxil 250mg Syrup/Suspension should be stored in a secure and controlled environment, preferably in a cool and dry place at room temperature, ensuring it is protected from direct sunlight, heat, and moisture. Keep the medication in its original container, tightly sealed, to maintain its integrity and prevent contamination. It is crucial to adhere to the recommended storage conditions to preserve the effectiveness of the medication. When disposing of unused or expired Cefadroxil syrup, do not dispose of it via household waste or sewage systems. Instead, contact your pharmacist or local waste management authorities for guidance on safe disposal practices to minimize any potential environmental impact. Always keep medications out of the sight and reach of children to prevent accidental consumption.

Following are the quick tips for Cefadroxil 250mg Syrup/Suspension:

• Always follow the prescribed dosage and duration as directed by your healthcare professional.
• Shake the bottle well before each use to ensure a consistent dose.
• Administer the syrup with a measuring cup or syringe provided to ensure accuracy.
• Take the medication with a full glass of water to aid in swallowing.
• Maintain a consistent schedule for taking the syrup to maximize its effectiveness.
• Store the medication at room temperature, away from excessive heat and moisture.
• Dispose of any unused or expired medication safely, following local guidelines.
• Consult your doctor if you have any concerns or experience side effects during treatment.

Before taking the antibiotic Cefadroxil, it is crucial to inform your doctor about your medical history and any other drugs or supplements you are currently taking. Certain conditions, such as kidney disease, can affect how your body absorbs or metabolizes the drug, as well as whether it will interact with other medications. Additionally, factors such as age, gender, and pregnancy status can also influence the efficacy and safety of Cefadroxil.To ensure that Cefadroxil is safe and effective for you, a proper lab evaluation is required. This may include a blood chemistry assessment to examine kidney function and electrolyte levels, a complete blood count to check for signs of anemia, infection, or bleeding, and monitoring of liver function tests to identify any signs of liver damage.A follow-up test may be prescribed by your doctor to ensure that the treatment is working and that Cefadroxil is safely eliminating the infection. However, it is important to note that not all individuals taking Cefadroxil will require these lab tests. Depending on your medical history and condition, your doctor will determine which tests are appropriate for you.