Econaphen Cream 10g

Econazole Nitrate, Triamcinolone Cream combines two active ingredients with different mechanisms of action. Econazole nitrate belongs to the imidazole class of antifungals and exerts its antifungal effect by inhibiting the synthesis of ergosterol, a critical component of the fungal cell membrane. This inhibition disrupts the membrane integrity, leading to impaired fungal cell growth and eventual cell death. Triamcinolone, a synthetic corticosteroid, has potent anti-inflammatory properties. It works by binding to corticosteroid receptors within cells, suppressing the production of pro-inflammatory molecules, and reducing inflammation. This dual action makes the cream effective in treating skin conditions where both fungal infections and inflammation are present, providing both antifungal and anti-inflammatory benefits.

Econazole Nitrate, Triamcinolone

Antifungal, Corticosteroid

Cream

The following are the uses of Econazole Nitrate, Triamcinolone Cream:

• Used for treating fungal skin infections such as athlete's foot, jock itch, and ringworm.
• Used to reduce inflammation and itching caused by various skin conditions like eczema and psoriasis.
• Used to alleviate redness, swelling, and discomfort in affected areas.
• Used for managing skin reactions to insect bites or minor skin injuries.
• Used to prevent the spread of infection and promote healing.
• Used as a combination medication for its anti-inflammatory and antifungal properties.

In the case of an overdose of Econazole Nitrate, Triamcinolone Cream, symptoms may include skin irritation, redness, and itching at the application site. If ingested, nausea, vomiting, and stomach discomfort could occur. In such instances, promptly wash the affected area with mild soap and water, and if symptoms persist or worsen, seek medical advice. It is advisable to keep this medication out of reach of children to prevent accidental ingestion or misuse.

In the case of a missed dose of Econazole Nitrate, Triamcinolone Cream, it is generally recommended to apply the medication as soon as you remember. However, if it's almost time for your next scheduled application, skip the missed dose and continue with your regular dosing schedule. Do not apply extra cream to make up for a missed dose, as this may increase the risk of side effects. It's important to maintain a consistent application routine for this medication to ensure its effectiveness. If you frequently miss doses, inform your healthcare provider, who can provide guidance on how to best manage your treatment.

To apply Econazole Nitrate and Triamcinolone Cream, clean and dry the affected skin area, then apply a thin layer of the cream to the skin, gently rubbing it in, usually twice a day or as directed by your doctor, ensuring not to exceed the prescribed dosage.

Following are the conditions/situations when Econazole Nitrate, Triamcinolone Cream should not be used:

• Should not be used on individuals with a known allergy or sensitivity to any of the active ingredients, such as Econazole Nitrate or Triamcinolone Acetonide, or any of the cream's components.
• Avoid using on skin with viral, bacterial, or fungal infections, especially tuberculosis or herpes infections, unless directed by a healthcare professional.
• Not suitable for individuals with thin skin or skin conditions like rosacea or perioral dermatitis.
• Do not use on skin with acne, open wounds, or broken skin.
• Should not be used on skin affected by chickenpox or shingles.
• Contraindicated for individuals with a recent history of skin thinning due to steroid use.
• Do not use on skin areas with skin atrophy (wasting).
• Not recommended for individuals with a history of skin reactions after vaccination.
• Avoid using on skin that will be exposed to sunlight or UV light, as it may cause photosensitivity.
• Do not use near the eyes or on the eyelids.
• Not suitable for individuals with diabetes, as steroids can increase blood sugar levels.
• Should not be used on children under 6 years of age unless prescribed by a doctor.

The side effects of Econazole Nitrate, Triamcinolone Cream may include:

• Skin irritation at the application site, such as redness, itching, or burning.
• Dryness or peeling of the skin.
• Thinning of the skin, making it more fragile and prone to bruising.
• Acne or pimples.
• Allergic reactions, including rash, hives, or itching.
• Increased hair growth in the treated area.
• Changes in skin color, making it lighter or darker.
• Eye problems such as glaucoma or cataracts when applied near the eyes.

Following are the precautions and warnings for Econazole Nitrate, Triamcinolone Cream:

• Do not use if you are allergic to any of the ingredients in the cream, including econazole nitrate or triamcinolone.
• Avoid applying the cream on open wounds, eyes, or mucous membranes.
• Wash your hands thoroughly before and after application to avoid accidental contact with sensitive areas.
• If you are pregnant or breastfeeding, consult your doctor before using this medication.
• This cream is for external use only and should not be ingested or used near the mouth or nose.
• Do not use this medication for prolonged periods without consulting your doctor, as prolonged use may lead to skin thinning and other adverse effects.
• Discontinue use and seek medical attention if you experience severe irritation, redness, or any signs of an allergic reaction.

Following are the drug interactions for Econazole Nitrate, Triamcinolone Cream:

• It can increase the systemic absorption of corticosteroids when used with other potent topical corticosteroids, leading to potential systemic side effects.
• Avoid using with other topical anti-inflammatory drugs due to potential additive effects and increased risk of adverse reactions.
• Econazole may inhibit the metabolism of certain drugs metabolized by CYP450 enzymes, resulting in increased levels of these medications.
• The cream may reduce the effectiveness of some live attenuated virus vaccines, such as measles, mumps, and rubella vaccines, when applied on the vaccination site.
• Topical corticosteroids like triamcinolone may interact with drugs that affect the metabolism of corticosteroids, such as rifampicin, leading to reduced efficacy.
• Using with other topical medications may increase the risk of skin atrophy, striae, or absorption of other drugs due to enhanced penetration.
• The cream should not be used with other potent skin irritants or sensitizers, as it may increase the risk of skin reactions.

Following are the food interactions for Econazole Nitrate, Triamcinolone Cream:

• Avoid consuming grapefruit or grapefruit juice as it may lead to increased drug levels in the body, potentially causing adverse effects.
• Alcoholic beverages should be limited or avoided as they can increase the skin's sensitivity and worsen side effects like skin dryness, redness, or irritation.
• Dairy products and foods rich in calcium, such as milk, cheese, and yogurt, may reduce the absorption of Triamcinolone, thus affecting its effectiveness.
• Fatty or greasy foods might interfere with the absorption of Econazole Nitrate, potentially reducing its antifungal activity.
• Caffeinated beverages like coffee, tea, and energy drinks should be consumed in moderation as they may increase skin sensitivity and dryness.
• Spicy foods can cause skin flushing and may potentially worsen skin irritation, especially when used with Triamcinolone.
• Foods rich in vitamin K, like leafy greens, broccoli, and soybeans, might interact with Triamcinolone, affecting blood clotting.
• Avoid consuming foods with high sugar content, as they can promote fungal growth and reduce the effectiveness of Econazole Nitrate.

Econazole Nitrate, Triamcinolone Cream should be stored in a cool and dry place, preferably at room temperature, ensuring it is protected from direct sunlight and moisture. Keep the cream inside its original packaging, tightly sealed, to maintain its integrity and prevent contamination. Avoid storing it in hot environments like near a stove or inside a bathroom cabinet, as heat and humidity can impact its effectiveness. Always check the expiration date, and if the cream has passed its expiry, do not use it and dispose of it responsibly. When discarding the cream, do not pour it down the drain or flush it; instead, consult a pharmacist or healthcare professional for appropriate disposal methods. Lastly, ensure the cream is kept in a secure location, out of the reach of children, to prevent any accidental exposure.

Following are the quick tips for Econazole Nitrate, Triamcinolone Cream:

• Wash and dry the affected area before applying the cream.
• Apply a thin layer of the cream to the affected area as directed by your doctor.
• Gently rub the cream into the skin until it is evenly absorbed.
• Avoid applying the cream to broken or irritated skin.
• Wash your hands after application to avoid accidental contact with eyes or mouth.
• Do not cover the treated area with bandages or tight clothing.
• Store the cream at room temperature, away from direct sunlight and moisture.