Empagen-M (5/500mg) 14 Tablets

Empagen-M (5/500mg) 14 Tablets

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  • Manufacturer Ferozsons Laboratories Ltd.
  • Generic Name Metformin, Empagliflozin

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Storage/Disposal
  • Description

    Empagliflozin 5mg and Metformin Hydrochloride 500mg constitute a fixed-dose combination medication utilized for the treatment of type 2 diabetes. Empagliflozin acts by inhibiting glucose reuptake in the kidneys, leading to heightened glucose excretion in urine, thereby reducing blood sugar levels. It also positively influences insulin sensitivity, diminishes endogenous glucose production, and contributes to weight loss, while simultaneously mitigating cardiovascular mortality risks in adults with type 2 diabetes prone to cardiovascular death. Meanwhile, metformin, a widely prescribed anti-diabetes drug, operates by suppressing glucose production in the liver and enhancing glucose uptake and utilization in peripheral tissues without inducing hypoglycemia or hyperinsulinism. The synergistic effects of empagliflozin and metformin, with their distinct mechanisms of action, make this combination more efficacious in managing type 2 diabetes compared to monotherapy. Physicians recommend prescribing this medication in conjunction with dietary and lifestyle interventions.

  • Ingredients

    Metformin, Empagliflozin
  • Drug Class

    Empagliflozin:

  • Dosage Form

    Tablet
  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Empagliflozin 5mg is used to improve blood sugar control in adults with type 2 diabetes mellitus
    • It is also used to reduce the risk of diabetes related complications such as heart attacks, stroke, or death in adults with type 2 diabetes mellitus and cardiovascular disease
    • Metformin Hydrochloride 500mg is used in addition to diet and exercise in adults with type 2 diabetes mellitus who have not reached their blood sugar goals on diet and exercise alone
    • Metformin Hydrochloride 500mg can also be used in combination with insulin or sulfonylureas when these drugs are not sufficiently effective or when there is a need to reduce the dose of these drugs
    • It is also used to treat gestational diabetes mellitus in pregnant women who are already taking insulin.
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • For Empagliflozin 5mg - Adults with type 2 diabetes mellitus to improve glycemic control in combination with diet and exercise- initially 5 mg once daily in the morning. May increase to a maximum of 10 mg once daily if glycemic control is not adequate.
    • For Empagliflozin 5mg - Adults with type 2 diabetes mellitus, to be used in combination with Metformin Hydrochloride 500mg or Thiazolidinedione (Glitazone) for improved glycemic control- initially 5 mg once daily. May increase to a maximum of 10 mg once daily if glycemic control is not adequate.
    • For Metformin Hydrochloride 500mg - Adults with type 2 diabetes, the recommended starting dose is 500 mg P.O. twice daily with meals. The dosage should be adjusted individually, primarily based on the goal preprandial blood glucose level. The maximum daily dose should not exceed 2500 mg.
  • In case of Overdose

    Empagliflozin 5mg and Metformin Hydrochloride 500mg overdose can be treated with general supportive care, which involves monitoring the patient's vital signs, oxygenation, and blood glucose levels. Depending on the severity of the overdose and the individual's overall health, additional treatments may include administering medications to counteract the effects of these drugs or inducing vomiting if the overdose is recent to reduce the amount of medication absorbed. The success of these treatments varies and hinges on prompt medical attention to ensure the patient's well-being, alleviate adverse symptoms, and prevent further health complications.

  • Missed Dose

    If you miss a dose of your medication, take the missed dose as soon as you can unless it is closer in time to your next scheduled dose. If you miss a dose and it is almost time for your next scheduled dose, skip the missed dose and take your regular dose as scheduled. Do not double up on your next dose to make up for the missed one, as this may result in an overdose. It is vital to maintain a regular dosing schedule to ensure the medication's effectiveness and minimize the risk of side effects. If you have any concerns or questions about missing a dose, consult a healthcare professional, such as your doctor or pharmacist, for specific guidance.

  • How To Use

    Before you start taking Empagliflozin 5mg and Metformin Hydrochloride 500mg, it is important to read the medication guide provided by your pharmacist. This guide will provide you with important information about your medication and how to take it properly. If you have any questions, be sure to ask your doctor or pharmacist. Taking this medication is simple. Generally, you should take it once daily with breakfast or the first meal of the day. Ensure that you swallow the tablets whole, without crushing or chewing them, as this can affect the drug's effectiveness. It is normal for the dosage to be based on your medical condition, your doctor's recommendations, and the use of other medications. Be sure to inform your doctor and pharmacist about all the products you use to avoid any potential interactions. It is also essential to disclose your full medical history and any allergies you may have to ensure your safety while taking these medications. If you have any concerns about taking this medication, consult with your healthcare provider, as they can provide personalized guidance based on your circumstances.

  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • You have an allergy or hypersensitivity to Empagliflozin or Metformin Hydrochloride.
    • You experience severe kidney impairment or acute kidney injury. Metformin can cause lactic acidosis, exacerbating lactic acid build-up in the blood.
    • You have a personal or family history of pancreatic cancer. Metformin may be associated with an increased risk of pancreatic cancer.
    • You are already taking other medications that may interact with Empagliflozin or Metformin.
  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Edema
    • Confusion
    • Vertigo
    • Headache
    • Diarrhea
    • Vomiting
    • Constipation
    • Heart palpitations
  • Storage/Disposal

    Empagliflozin 5mg and Metformin Hydrochloride 500mg are two distinct medications that require specific storage conditions to preserve their efficacy and safety. Empagliflozin is an SGLT2 inhibitor prescribed to treat type 2 diabetes mellitus. It is available as tablets and should be stored at room temperature, away from light and moisture. The ideal storage range is roughly 20°C (-5.5°C to 25°C), so it is important to keep the container securely closed and out of the reach of children and pets. Metformin Hydrochloride is also used to treat type 2 diabetes mellitus and belongs to a class of drugs called biguanides. This medication is available as tablets, extended-release tablets, or an oral solution. Metformin Hydrochloride tablets and oral solutions should be stored at room temperature, ideally between 15°C and 30°C (59°F and 86°F). In contrast, the extended-release tablets should be stored within a temperature range of 20°C and 25°C (68°F and 77°F). To ensure the optimal effectiveness of these drugs, it is crucial to adhere to the storage instructions on the medication label. Ensure the containers are tightly closed and stored away from direct sunlight, heat, and moisture. If you have any questions or concerns about storing these medications, consult a healthcare professional for guidance.

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