EPINUM CRAM 30GM

Lidocaine cream is a local anesthetic that primarily works by blocking voltage-gated sodium channels in nerve cell membranes. When applied topically, lidocaine molecules penetrate the skin and reach the sensory nerves. Upon reaching the nerve endings, lidocaine inhibits the initiation and conduction of nerve impulses by preventing the movement of sodium ions into the nerve cells. This action stabilizes the neuronal membrane and prevents the generation and propagation of action potentials, resulting in temporary numbness and pain relief in the treated area. By blocking the transmission of pain signals from the nerves to the brain, lidocaine cream effectively provides localized anesthesia and reduces the sensation of pain without causing unconsciousness or affecting the central nervous system.

Lidocaine, Prilocaine

Anesthetic

Cream

The following are the uses of Lidocaine Cream:

• Used for numbing the skin and mucous membranes, providing effective pain relief.
• Used for treating minor skin irritations, insect bites, and itching.
• Used for relieving pain and discomfort during various medical procedures.
• Used for reducing discomfort in conditions like sunburn, minor burns, and skin allergies.
• Used for managing nerve-related pain, such as shingles and diabetic neuropathy.
• Used for local anesthesia in minor surgical procedures, ensuring patient comfort.
• Used for easing the insertion of medical instruments, making the process less painful.
• Used for soothing skin inflammation and promoting faster healing.

In the case of an overdose of Lidocaine Cream, it is important to recognize the potential severity of the situation. Overapplication or ingestion of this medication can lead to serious adverse effects. Symptoms may include dizziness, drowsiness, tremors, and in severe cases, seizures or cardiac arrhythmias. If an overdose is suspected, seek medical advice promptly. Timely intervention can help mitigate the risks associated with excessive exposure to Lidocaine Cream.

In the case of a missed dose of Lidocaine Cream, it is important to apply the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra cream to make up for the missed dose, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare professional for advice on how to get back on track with your medication regimen safely. It is always best to follow the prescribed instructions for using Lidocaine Cream.

To apply Lidocaine Cream, clean and dry the affected area, then apply a thin layer of the cream onto the skin, gently massaging it until it is thoroughly absorbed, following the instructions provided by your healthcare professional regarding the frequency and duration of application.

Here are the conditions and situations when Lidocaine Cream should not be used:

• Must not be used if you have a known allergy or sensitivity to Lidocaine or any of the cream's components.
• Avoid using it on open wounds, broken skin, or severe skin conditions such as eczema, psoriasis, or severe skin infections.
• Not suitable for individuals with a history of metabolic conditions, especially those with a deficiency in pseudocholinesterase.
• Do not use it on mucous membranes or inside the mouth, nose, or eyes.
• Contraindicated for areas of skin that are inflamed, irritated, or infected due to reasons other than the intended use.
• Should not be used on skin that is already numb or has reduced sensation.
• Avoid using it on skin with impaired circulation, as it may affect the absorption and effectiveness.
• Not recommended for infants or young children without medical supervision.

The side effects of Lidocaine Cream may include:

• Skin redness and irritation at the application site
• Itching or rash
• Swelling or inflammation
• Numbness or tingling sensation
• Allergic reactions (skin hives, itching, or difficulty breathing)
• Burning or stinging sensation
• Skin dryness or peeling

Following are the precautions and warnings:

• Lidocaine Cream should be used with caution in patients with known allergies to local anesthetics, as it may cause allergic reactions.
• Avoid contact with eyes, nose, and mouth. In case of accidental contact, immediately flush with water.
• Do not apply to broken or infected skin, and do not use on large areas of skin without medical advice.
• This medication is for external use only. Do not ingest or swallow.
• If you are pregnant or breastfeeding, consult your healthcare provider before using Lidocaine Cream, as the effects on fetal development and nursing infants are not fully established.
• Keep out of reach of children. If swallowed, seek immediate medical attention as it can cause serious side effects when taken internally.
• Lidocaine Cream may cause temporary numbness or tingling at the application site; if these sensations persist or worsen, discontinue use and consult a healthcare professional.
• Avoid using occlusive dressings or bandages over the treated area, as this may increase the risk of adverse effects.

Following are the drug interactions for Lidocaine Cream:

• Lidocaine may interact with other topical anesthetics or medications containing local anesthetics, potentially increasing the risk of adverse effects.
• Avoid using with other sodium channel blockers, as it may enhance the effects of lidocaine and lead to toxicity.
• The use of Lidocaine Cream with epinephrine-containing drugs can result in elevated blood pressure and abnormal heart rhythms.
• It may increase the effects of neuromuscular blocking agents, requiring dosage adjustments.
• Lidocaine can interact with Class I antiarrhythmic drugs, potentially affecting the heart's electrical activity.
• Using Lidocaine Cream with other medications that lower the seizure threshold, such as certain antidepressants or antipsychotics, may increase the risk of seizures.
• Alcohol and Lidocaine Cream together can enhance the sedative effects of both substances, impairing cognitive function.

Following are the food interactions to consider with Lidocaine Cream:

• Lidocaine Cream should be used with caution if you consume methylxanthines like caffeine (found in coffee, tea, chocolate) or theobromine (in tea), as these substances may enhance the effects of Lidocaine, potentially leading to increased numbness or other side effects.
• Alcohol is not known to directly interact with Lidocaine Cream, but it can impair your judgment and increase the risk of injury, especially if the cream is applied to large areas or used excessively.
• Avoid applying the cream immediately after a hot meal, as increased blood flow to the skin may affect the absorption of Lidocaine.
• Grapefruit and grapefruit juice are not known to have a significant interaction with Lidocaine Cream, unlike some other medications.
• No specific restrictions on dairy products, meat, or other common food groups are associated with Lidocaine Cream.
• Always follow the instructions provided by your healthcare provider regarding the use of Lidocaine Cream, including any dietary advice specific to your condition.
• If you have any concerns or questions about potential food interactions, consult your healthcare provider for personalized advice.

Lidocaine Cream should be stored in a cool and dry place, preferably at room temperature, ensuring it is kept away from direct sunlight, heat, and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial not to store the cream in extreme temperatures, such as the bathroom or near heat sources, as this can impact its effectiveness. Always check the expiration date, and if the cream has passed its expiry, proper disposal is essential. Do not dispose of it in the toilet or down the drain; instead, consult a pharmacist or healthcare professional for guidance on safe disposal methods. Keep the cream out of children's reach to prevent accidental exposure.

Following are the quick tips for Lidocaine Cream:

• Apply a thin layer to the affected area as directed by your doctor or pharmacist.
• Wash your hands before and after application to maintain hygiene.
• Avoid contact with eyes, nose, and mouth during application.
• Do not cover the treated area with a bandage unless instructed by your healthcare provider.
• Do not apply to broken or irritated skin.
• Store the cream at room temperature, away from direct sunlight and moisture.
• Inform your doctor if you are pregnant or breastfeeding before using this cream.