Epuram (250/75/200mg) 120ml Suspension

L-Arginine Monohydrochloride and L-citrulline work synergistically to enhance nitric oxide (NO) production in the body. L-Arginine is a precursor to NO, and when it is metabolized by the enzyme nitric oxide synthase, it produces NO. L-citrulline, on the other hand, is a byproduct of this process and can be recycled back into L-arginine, ensuring a continuous supply for NO synthesis. This increased NO production promotes vasodilation, improves blood flow, and supports cardiovascular health by relaxing blood vessels and preventing platelet aggregation.

L-Arginine Monohydrochloride 250mg, L-citrulline 75mg

Nitric Oxide Enhancers

Suspension

The following are the uses of L-Arginine Monohydrochloride 250mg, L-citrulline 75mg Syrup/Suspension:

• Used for improving blood flow and circulation, especially in conditions like peripheral artery disease.
• Used for enhancing athletic performance and exercise capacity by increasing nitric oxide production.
• Used for supporting heart health and managing blood pressure.
• Used for treating erectile dysfunction and improving sexual function.
• Used for wound healing and tissue repair, particularly in burn patients.
• Used for managing chronic kidney disease and reducing the risk of cardiovascular events.
• Used for enhancing immune function and supporting overall health.
• Used for potentially aiding in the treatment of certain gastrointestinal disorders.

In the case of an overdose of L-Arginine Monohydrochloride 250mg and L-citrulline 75mg Syrup/Suspension, individuals may experience symptoms such as nausea, vomiting, diarrhea, and abdominal pain. It is important to seek medical advice promptly and provide the healthcare professional with information about the amount ingested. Treatment for overdose may involve managing symptoms and providing supportive care under medical supervision.

In the case of a missed dose of L-Arginine Monohydrochloride 250mg and L-citrulline 75mg Syrup/Suspension, take the missed dose as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Avoid taking extra doses to make up for a missed one, as this may lead to potential side effects. Consult your healthcare provider if you frequently miss doses or have concerns about your medication regimen.

To administer L-Arginine Monohydrochloride 250mg and L-citrulline 75mg syrup/suspension, measure the prescribed dose using an oral syringe or measuring cup, ensuring accuracy, and take it orally once or twice a day as directed by your healthcare professional, with or without food, following the recommended dosage guidelines.

Following are the conditions or situations when L-Arginine Monohydrochloride 250mg, L-citrulline 75mg Syrup/Suspension should not be used:

• Not suitable for individuals with a known allergy or hypersensitivity to L-Arginine, L-citrulline, or any other ingredients in the syrup/suspension.
• Should not be administered to patients with severe liver or kidney disease.
• Contraindicated in individuals with a history of herpes outbreaks, as it may trigger or worsen symptoms.
• Not recommended for patients with a history of gastrointestinal bleeding or active peptic ulcer disease.
• Avoid using in patients with uncontrolled high blood pressure.
• Should not be used in patients with a history of blood clots or stroke.
• Contraindicated during pregnancy and breastfeeding.

The side effects of L-Arginine Monohydrochloride 250mg and L-citrulline 75mg Syrup/Suspension may include:

• Nausea and vomiting.
• Diarrhea or loose stools.
• Stomach pain or cramps.
• Dizziness or lightheadedness.
• Headaches.
• Skin flushing or redness.
• Changes in blood pressure (either increase or decrease).
• Increased risk of bleeding (especially if taken with anticoagulant medications).

Following are the precautions and warnings for L-Arginine Monohydrochloride 250mg, L-citrulline 75mg Syrup/Suspension:

• This medication should be used with caution in patients with a history of allergies or asthma, as it may trigger allergic reactions.
• Patients with liver or kidney disease should be monitored closely as the dosage may need adjustment.
• Do not exceed the recommended dosage, as high doses of L-arginine may cause gastrointestinal distress and worsen asthma symptoms.
• L-arginine may interact with certain medications, including blood pressure medications, so consult your doctor if you are on any medication.
• Avoid driving or operating heavy machinery if you experience dizziness or sleepiness after taking this medication.
• Pregnant and breastfeeding women should consult their doctor before use, as there is limited research on its safety during these periods.
• Keep out of reach of children. Store in a cool, dry place, away from direct sunlight.

Following are the drug interactions for L-Arginine Monohydrochloride 250mg, L-citrulline 75mg Syrup/Suspension:

• L-Arginine may decrease blood pressure, and combining it with antihypertensive medications can lead to excessive blood pressure drop.
• It can interact with Nitrates, potentially causing a significant drop in blood pressure.
• The effect of antidiabetic medications may be enhanced by L-Arginine, increasing the risk of hypoglycemia.
• L-Arginine may increase the effectiveness of certain immune-boosting medications.
• Use with caution alongside anticoagulants/antiplatelet drugs, as it may increase bleeding risk.
• May interact with Viagra and similar medications, potentially causing an unsafe drop in blood pressure.
• Consult a doctor before using L-Arginine with any herbal supplements, especially those affecting blood pressure or blood sugar.

Following are the food interactions for L-Arginine Monohydrochloride 250mg and L-citrulline 75mg Syrup/Suspension:

• Consuming citrus fruits like oranges, lemons, and grapefruits can influence the absorption of L-arginine, potentially affecting its effectiveness.
• Avoid excessive caffeine intake as it may counteract the relaxing effects of L-arginine and L-citrulline on blood vessels.
• Limit the consumption of high-fat meals as they may delay the absorption of these amino acids.
• Alcohol should be consumed in moderation, as it can affect blood flow and potentially interact with the vascular effects of L-arginine.
• Avoid consuming large amounts of refined sugar, as it may interfere with the benefits of L-arginine and L-citrulline on insulin sensitivity.
• Dark chocolate, known for its flavonoid content, may have synergistic effects with L-arginine and L-citrulline, promoting cardiovascular health.
• Foods rich in nitrates, such as beets and spinach, can enhance the production of nitric oxide when combined with L-arginine, supporting overall cardiovascular function.
• While not a food, it's important to maintain adequate hydration when taking this syrup to support overall circulation and nutrient delivery.

L-Arginine Monohydrochloride 250mg and L-citrulline 75mg Syrup/Suspension should be stored in a controlled environment, preferably in a cool and dry place, away from direct sunlight and moisture. It is crucial to maintain the integrity of the medication by keeping the container tightly sealed, ensuring it remains uncontaminated. Avoid exposure to extreme temperatures, including heat sources and direct sunlight, as this can impact the syrup's effectiveness. Proper disposal is essential; do not discard it in household waste or pour it down the drain. Consult your pharmacist for guidance on environmentally friendly disposal methods, and keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for L-Arginine Monohydrochloride 250mg, L-citrulline 75mg Syrup/Suspension:

• Consult a healthcare professional for dosage instructions based on your specific needs.
• Shake the bottle vigorously before each use to ensure a well-mixed solution.
• Administer the syrup with water; avoid tea, coffee, or dairy for optimal absorption.
• Maintain a consistent daily dosing schedule for best results.
• If stomach discomfort occurs, consider taking it with food or after meals.
• Store the syrup safely, away from children, to prevent accidental consumption.
• Always complete the full course of medication as prescribed.