Eraxib (200mg) 10 Tablets

Celecoxib 100mg Tablet is a selective non-steroidal anti-inflammatory drug (NSAID) that primarily inhibits the enzyme cyclooxygenase-2 (COX-2). COX-2 is responsible for the production of prostaglandins, which play a key role in pain and inflammation. By selectively blocking COX-2, celecoxib reduces the formation of these inflammatory mediators, thereby providing pain relief and reducing inflammation. It has a preferential affinity for COX-2 over COX-1, which helps minimize the gastrointestinal side effects associated with traditional NSAIDs that inhibit both COX enzymes. This mechanism of action makes celecoxib effective in treating conditions such as arthritis, acute pain, and certain types of chronic pain.

Celecoxib 100mg

COX-2 Inhibitor

Tablet

The following are the uses of Celecoxib 100mg Tablet:

• Used for relieving pain and inflammation associated with osteoarthritis and rheumatoid arthritis.
• Used to manage acute pain and discomfort post-surgery.
• Effective for reducing menstrual pain and cramps.
• Helps in alleviating pain and inflammation in ankylosing spondylitis, a type of arthritis affecting the spine.
• Used to treat painful mouth sores and reduce the number of new sores.
• Provides relief from pain and swelling caused by gout.
• Can be used for managing other painful conditions as advised by a doctor.

In the case of an overdose of Celecoxib 100mg Tablets, individuals may experience symptoms such as dizziness, drowsiness, and gastrointestinal issues like nausea, vomiting, or stomach pain. The severity of symptoms can vary depending on the amount ingested. It is important to seek medical advice promptly if an overdose is suspected, as healthcare professionals can provide guidance and treatment to manage any adverse effects and ensure the individual's well-being. Timely intervention can help mitigate potential health risks associated with overdosing on this medication.

In the case of a missed dose of Celecoxib 100mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare provider for guidance on how to safely resume your medication and ensure the best treatment outcome.

To take Celecoxib 100mg Tablet, swallow the tablet whole with a full glass of water, preferably with food, once or twice a day as directed by your doctor, and do not crush, chew, or break the tablet.

Following are the conditions/situations when Celecoxib 100mg Tablet should not be used:

• Do not take if you have a known allergy to Celecoxib or any other sulfonamide-derived drugs.
• Avoid using this medication if you have a history of severe allergic reactions, such as anaphylaxis, to other non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin, ibuprofen, or naproxen.
• Should not be used in individuals with severe heart-related problems, including recent heart attack, angina, or uncontrolled heart failure.
• Contraindicated in patients with confirmed or suspected gastric or intestinal ulcers or bleeding.
• Not recommended for individuals with severe kidney problems or those with significantly impaired kidney function.
• Avoid using this medication if you have recently undergone coronary artery bypass graft (CABG) surgery.
• Should not be used in patients with severe liver impairment or active liver disease.
• Do not take this medication if you are in the third trimester of pregnancy as it may cause harm to the unborn baby.
• Not suitable for individuals with a rare genetic problem of galactose intolerance, severe lactase deficiency, or glucose-galactose malabsorption.

The side effects of Celecoxib 100mg Tablet may include:

• Stomach pain or discomfort
• Nausea and vomiting
• Diarrhea or constipation
• Dizziness or lightheadedness
• Headache
• Skin rash or itching
• Swelling of the legs and ankles (peripheral edema)
• Increased blood pressure

Following are the precautions and warnings for Celecoxib 100mg Tablet:

• This medication is not suitable for individuals who have a known allergy to celecoxib or any other ingredients in the tablet.
• Patients with a history of cardiovascular disease, hypertension, or congestive heart failure should use with caution and under medical supervision.
• Celecoxib may increase the risk of serious cardiovascular events, including heart attack and stroke, especially with long-term use. Regular monitoring is essential.
• Not recommended for individuals with a history of gastrointestinal bleeding or perforation.
• The elderly and patients with poor general health are at a higher risk of adverse reactions and should be closely monitored.
• Avoid alcohol consumption while taking this medication as it may increase the risk of gastrointestinal bleeding.
• Consult a doctor if you have a history of liver or kidney disease, as these conditions may require dosage adjustments.

Following are the drug interactions for Celecoxib 100mg Tablet:

• NSAIDs like ibuprofen or aspirin may increase the risk of gastrointestinal bleeding when taken with Celecoxib.
• Concomitant use with lithium can lead to increased lithium blood levels and potential lithium toxicity.
• May reduce the effectiveness of diuretics, such as furosemide, by inhibiting their renal excretion.
• Antihypertensive effects of ACE inhibitors and angiotensin II receptor blockers may be diminished when used with Celecoxib.
• The risk of kidney damage is higher when combined with diuretics or ACE inhibitors, especially in dehydrated patients.
• Warfarin and other anticoagulants may have their effects potentiated, requiring close monitoring of INR.
• Celecoxib can increase plasma concentrations of medications metabolized by CYP2C9 and CYP3A4 enzymes, such as oral hypoglycemic agents and certain antibiotics.

Following are the food interactions for Celecoxib 100mg Tablet:

• Grapefruit and grapefruit juice should be avoided as they may interfere with the metabolism of Celecoxib, potentially increasing its levels in the blood and the risk of side effects.
• Limit alcohol consumption as it can increase the risk of gastrointestinal bleeding and liver toxicity when combined with Celecoxib.
• Avoid excessive caffeine intake, as it may enhance the effects of Celecoxib on the central nervous system, leading to increased nervousness or insomnia.
• Avoid high-sodium foods, as Celecoxib can cause sodium retention, and excessive sodium intake may exacerbate this effect, particularly in individuals with hypertension.
• Consuming fatty foods may not significantly affect the absorption of Celecoxib, but maintaining a balanced diet is advisable.
• Avoid herbal supplements like Ginkgo Biloba and St. John's Wort, as they may interact with Celecoxib and increase the risk of bleeding.
• Consult your doctor about specific dietary restrictions or recommendations based on your medical history.
• Always follow your healthcare provider's advice regarding food and medication interactions.

Celecoxib 100mg Tablets should be stored in a cool, dry area, preferably at room temperature, ensuring protection from light and moisture. It is crucial to keep the tablets in their original packaging, tightly sealed, to maintain their integrity and prevent contamination. Avoid exposing the medication to heat or cold extremes, such as in the refrigerator or near heating devices, as this can compromise its effectiveness. Always adhere to the expiration date indicated on the packaging, and when disposing of unused or expired tablets, do not flush them or pour them down the drain. Consult your pharmacist or local waste disposal guidelines for the appropriate method of disposal, ensuring environmental safety. Lastly, keep the medication securely stored away from children to prevent accidental consumption.

Following are the quick tips for Celecoxib 100mg Tablet:

• Take the tablet as directed by your doctor, usually once or twice daily.
• Swallow the tablet whole with a full glass of water, do not crush or chew.
• Take it with or after food to prevent stomach upset.
• Avoid alcohol consumption while taking this medication.
• Do not take other painkillers or anti-inflammatory drugs without doctor's advice.
• Inform your doctor about all medications you are currently taking.
• Store the tablets in a cool, dry place, away from direct sunlight.
• Contact your doctor if you experience any unusual symptoms or side effects.