Ercopd (175mg/5ml) Suspension

Erdosteine is a mucolytic agent that exerts its action primarily through its active metabolite, erdosteine sulfoxide. It works by breaking the disulfide bonds present in mucoproteins, thereby reducing the viscosity and elasticity of mucus. This mechanism helps to decrease mucus adhesiveness and improves its clearance from the respiratory tract. Erdosteine sulfoxide also possesses antioxidant properties, which contribute to its mucolytic effect by reducing oxidative stress and inhibiting the production of excess mucus. By modifying the rheological properties of mucus, erdosteine facilitates expectoration and improves respiratory function in conditions associated with excessive or thickened mucus secretion.

Erdosteine

Mucolytic expectorant.

Suspension

The following are the uses of Erdosteine Syrup/Suspension:

• Used for treating chronic obstructive pulmonary disease (COPD) and reducing the frequency of flare-ups.
• Used for thinning and breaking down mucus in the lungs, making it easier to cough up.
• Used for relieving symptoms of bronchitis and other respiratory infections by reducing mucus and soothing irritation.
• Used for managing cystic fibrosis by improving lung function and reducing the risk of infections.
• Used for reducing the severity and duration of acute bronchial infections.
• Used for facilitating easier breathing and improving overall respiratory health.
• Used for preventing the formation of respiratory secretions that can lead to further complications.
• Used for long-term management of respiratory conditions to improve quality of life.

In the case of an overdose of Erdosteine Syrup/Suspension, the patient may experience gastrointestinal symptoms such as nausea, vomiting, and abdominal pain. These symptoms are typically mild and self-limiting, but it is important to seek medical advice promptly. The severity of the overdose effects can vary depending on the amount ingested, and medical professionals should be consulted to determine the best course of action, which may include symptomatic treatment and monitoring.

In the case of a missed dose of Erdosteine Syrup/Suspension, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to proceed, as they may advise you to restart the medication or provide alternative instructions.

To administer Erdosteine Syrup/Suspension, shake the bottle well, measure the prescribed dose with an accurate measuring device, and take it orally once or twice a day as directed by your healthcare provider, with or without food, ensuring you follow the recommended dosage instructions for optimal effectiveness.

Here are the conditions or situations when Erdosteine Syrup/Suspension should not be used:

• Avoid using in patients with a known allergy or hypersensitivity to Erdosteine or any of its excipients.
• Not suitable for individuals with active peptic ulcer disease or gastrointestinal bleeding.
• Contraindicated in patients with severe liver or kidney impairment.
• Should not be administered to children under 2 years of age due to insufficient data on safety and efficacy.
• Avoid using in patients with a history of chronic or acute respiratory diseases, such as asthma or chronic obstructive pulmonary disease (COPD), unless closely monitored by a healthcare professional.
• Not recommended for individuals with a history of seizures or epilepsy, as it may lower the seizure threshold.
• Erdosteine should not be used in patients with a history of severe allergic reactions to other mucolytics or expectorants.
• Do not use if the patient is already taking other medications that may interact with Erdosteine, such as anticoagulants, without consulting a healthcare professional.

The side effects of Erdosteine Syrup/Suspension may include:

• Nausea and vomiting
• Stomach pain or discomfort
• Diarrhea
• Constipation
• Skin rashes or itching
• Dizziness or lightheadedness
• Headache
• Altered taste sensation

Following are the precautions and warnings for Erdosteine Syrup/Suspension:

• Do not use in patients with a known hypersensitivity or allergy to Erdosteine or any of its excipients.
• This medication should be used with caution in patients with impaired liver function, as it may require dosage adjustments.
• Patients with a history of gastrointestinal disorders, such as peptic ulcers or gastrointestinal bleeding, should be monitored closely while on this medication.
• Erdosteine may cause dizziness or blurred vision, so patients should avoid driving or operating heavy machinery until they know how the medication affects them.
• Not recommended for use in children under 12 years of age due to insufficient data on safety and efficacy.
• Elderly patients may be more susceptible to side effects, so monitoring for any adverse reactions is crucial.
• Pregnant and breastfeeding women should consult their doctor before taking this medication, as its safety during pregnancy and lactation has not been fully established.
• If symptoms persist or worsen, or if you experience any severe side effects, consult your healthcare professional immediately.

Following are the drug interactions for Erdosteine Syrup/Suspension:

• May interact with other mucolytic agents, such as acetylcysteine, increasing the risk of respiratory adverse effects.
• Erdosteine can affect the absorption of other medications due to its effect on mucus production, potentially reducing the effectiveness of oral contraceptives.
• Antibiotics like amoxicillin and erythromycin may have reduced absorption when taken concurrently with Erdosteine.
• It may increase the bioavailability of certain medications like theophylline, requiring dosage adjustments.
• Erdosteine should be used cautiously with anticoagulants, as it may enhance their effects and increase bleeding risk.
• Avoid using Erdostein with medications that are known to cause respiratory depression, as it may increase this risk.
• The syrup formulation may affect the absorption of other concurrently administered drugs, requiring careful monitoring.

Following are the food interactions for Erdosteine Syrup/Suspension:

• Alcohol consumption should be avoided as it can potentially irritate the stomach and throat, especially when combined with Erdosteine, which may increase the risk of gastrointestinal side effects.
• Citrus fruits like oranges, lemons, and grapefruits should be consumed with caution as they can potentially irritate the throat and esophagus, especially in individuals with existing gastrointestinal issues.
• Spicy and acidic foods should be approached with caution as they can sometimes trigger heartburn, acid reflux, or irritate the stomach lining, which may reduce the effectiveness of Erdosteine in treating respiratory conditions.
• Dairy products, especially milk, can sometimes interact with medications, affecting their absorption. It's best to consult a healthcare provider for specific instructions regarding dairy consumption with Erdosteine.
• Erdosteine should be taken on an empty stomach, at least 2 hours before or after a meal, for optimal absorption. Food can sometimes interfere with the medication's effectiveness.
• Caffeinated beverages like coffee and tea may increase stomach acid production, which could potentially reduce the effectiveness of Erdosteine in treating certain respiratory conditions.
• High-fat meals might delay the absorption of Erdosteine, potentially affecting its efficacy. It's advisable to maintain a balanced diet and follow the dosing instructions provided by your healthcare professional.

Erdosteine Syrup/Suspension should be stored in a controlled environment, preferably at room temperature between 15-25°C (59-77°F), in a dry place, away from direct sunlight and moisture. Keep the bottle tightly sealed to maintain its integrity and effectiveness. It is crucial to adhere to the recommended storage conditions to ensure the medication remains unadulterated. Dispose of any unused or expired syrup responsibly by following local guidelines or consulting a pharmacist; do not discard it via household waste or water systems. Always keep medicines out of children's reach to prevent accidental ingestion, ensuring their safety.

Following are the quick tips for Erdosteine Syrup/Suspension:

• Always follow the dosage instructions provided by your doctor or pharmacist.
• Administer the syrup using the provided measuring device for accuracy.
• Take the medication with a full glass of water to aid in swallowing and absorption.
• Avoid crushing or chewing the tablets; swallow them whole for optimal effectiveness.
• Store the medication at room temperature, away from direct sunlight and moisture.
• Do not share your medication with others, even if they have similar symptoms.
• Inform your doctor if you have any liver or kidney issues before taking Erdosteine.