Erdozet (150mg) 20 Capsules

Erdosteine's primary mechanism of action is centered on its ability to modulate the redox balance in the respiratory tract. It acts as a mucolytic and antioxidant agent, helping to break down and reduce the viscosity of mucus, thereby improving its clearance from the airways. The active metabolite of Erdosteine, erdostine disulfide, exerts its mucolytic effect by directly breaking the disulfide bonds in mucus glycoproteins, which contributes to mucus thinning and facilitates easier expectoration. Additionally, Erdosteine demonstrates antioxidant properties by scavenging reactive oxygen species (ROS) and increasing glutathione levels, which helps to reduce oxidative stress and inflammation in the respiratory system. This dual action makes Erdosteine effective in managing respiratory conditions characterized by excessive mucus production and oxidative damage.

Erdosteine

Mucolytic expectorant

Capsule

The following are the uses of Erdosteine Capsule:

• Used for treating acute and chronic bronchitis, reducing mucus production and easing cough.
• Used for thinning and loosening mucus in individuals with respiratory conditions.
• Used for managing symptoms of chronic obstructive pulmonary disease (COPD).
• Used for relieving congestion and reducing inflammation in the airways.
• Used for improving lung function and reducing the frequency of exacerbations.
• Used for treating upper respiratory tract infections and reducing symptoms.
• Used for providing antioxidant effects and protecting the lungs against oxidative stress.
• Used for supporting overall respiratory health and managing respiratory disorders.

In the case of an overdose of Erdosteine Capsules, it is important to recognize the potential symptoms and seek medical advice promptly. Overdose symptoms may include gastrointestinal issues such as nausea, vomiting, and abdominal pain. Additionally, individuals may experience dizziness, headache, and increased heart rate. If an overdose is suspected, it is recommended to contact a healthcare professional or a poison control center for guidance on the appropriate steps to take.

In the case of a missed dose of Erdosteine Capsule, it is important to take the missed dose as soon as you remember, provided there is a sufficient gap before your next scheduled dose. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. If you miss multiple doses, consult your healthcare professional for guidance on how to safely resume your medication regimen.

To take the Erdosteine Capsule, swallow the capsule whole with a full glass of water, preferably in the morning on an empty stomach, as directed by your healthcare professional, ensuring you follow the prescribed dosage and treatment duration.

Here are the conditions or situations when Erdosteine Capsule should not be taken:

• Allergy Not to be used if the patient has a known allergy or hypersensitivity to Erdosteine or any of its excipients.
• Liver Impairment Contraindicated in patients with severe liver impairment as it may worsen the condition.
• Peptic Ulcer Should not be used in individuals with active peptic ulcer disease.
• Pregnancy and Breastfeeding Not recommended for pregnant women and breastfeeding mothers due to limited safety data.
• Children Erdosteine is not suitable for children under 12 years of age.
• Hemorrhagic Conditions Avoid using in patients with a history of bleeding disorders or those taking anticoagulant medications.
• Respiratory Failure Not suitable for patients with severe respiratory failure.
• Allergic Reactions Discontinue use if any signs of allergic reactions, such as skin rash, itching, or difficulty breathing, occur.
• Surgery Should be stopped at least 48 hours before elective surgery.

The side effects of Erdosteine Capsule may include:

• Gastrointestinal discomfort
• Nausea and vomiting
• Stomach pain or cramps
• Diarrhea
• Skin rashes or itching
• Headache
• Dizziness
• Allergic reactions (rare)

Following are the precautions and warnings for Erdosteine Capsule:

• Not recommended for individuals with a known allergy to Erdosteine or related compounds.
• Patients with a history of liver or kidney disease should exercise caution and consult a healthcare professional before use, as dosage adjustments may be necessary.
• It is advisable to avoid excessive alcohol consumption while taking Erdosteine, as it may increase the risk of liver-related side effects.
• If you experience any gastrointestinal discomfort, such as nausea, vomiting, or diarrhea, consult your doctor immediately.
• Patients with a history of gastrointestinal disorders should use this medication with caution and under medical supervision.
• Erdosteine may cause dizziness or blurred vision in some individuals; avoid driving or operating heavy machinery if affected.
• Pregnant and breastfeeding women should consult their doctor before taking Erdosteine, as the risks and benefits should be carefully considered.

Following are the drug interactions for Erdosteine Capsule:

• Concomitant use with antibiotics like amoxicillin or erythromycin may increase the risk of gastrointestinal side effects, as Erdosteine can enhance the absorption of these antibiotics.
• Erdosteine can reduce the effectiveness of oral contraceptives, so alternative birth control methods should be considered during treatment.
• The absorption of tetracycline antibiotics may be reduced by Erdosteine, potentially decreasing their efficacy.
• Caution is advised when using Erdosteine with antacids, as it may decrease the absorption of both medications. Separate administration by at least 2 hours.
• The breakdown of Erdosteine may be slowed by medications like cimetidine, potentially increasing its levels in the body and the risk of side effects.
• Erdosteine may increase the bioavailability of digoxin, requiring close monitoring for signs of digoxin toxicity.
• It can interact with anticoagulants, such as warfarin, by enhancing their effects, which may increase the risk of bleeding. Regular monitoring of coagulation parameters is necessary.

Following are the food interactions to consider with Erdosteine Capsule:

• Grapefruit and grapefruit juice should be consumed with caution as they can inhibit the enzyme CYP1A2, which may increase the concentration of Erdosteine in the body, potentially enhancing its effects and the risk of side effects.
• Alcohol intake is generally not recommended while taking Erdosteine as it may increase the risk of liver toxicity and gastrointestinal irritation.
• Avoid high-fat meals as they can potentially decrease the absorption of Erdosteine, reducing its effectiveness.
• Caffeine-rich foods and beverages might interact with Erdosteine, leading to increased caffeine levels and potential side effects like insomnia and nervousness.
• Dairy products, especially milk, may decrease the absorption of Erdosteine, so it's best to take the medication at least an hour before or after consuming milk.
• Spicy foods can potentially irritate the stomach, especially when taking Erdosteine, and may increase the risk of gastrointestinal side effects.
• Ensure adequate hydration by drinking plenty of water during the course of Erdosteine treatment to aid in the medication's effectiveness and reduce the risk of side effects.
• Avoid excessive consumption of sugary foods as they may interact with Erdosteine's mucolytic properties, potentially affecting its effectiveness in managing respiratory conditions.

Erdosteine capsules should be stored in a cool, dry place, preferably at room temperature between 68°F and 77°F (20°C and 25°C). Protect the capsules from light and moisture by keeping them in their original packaging or container. It's crucial not to store them in the bathroom or near any heat sources like ovens or radiators, as temperature and humidity fluctuations can impact their effectiveness. Always check the expiry date, and never use capsules beyond this date. When disposing of unused or expired capsules, do not flush them or throw them into the trash. Instead, consult your pharmacist or healthcare professional for safe disposal options. Keep the medication away from children to prevent accidental consumption.

Following are the quick tips for Erdosteine Capsule:

• Take the capsule with water, preferably on an empty stomach, for better absorption.
• Swallow the capsule whole without crushing or chewing for optimal effect.
• Maintain a consistent dosing schedule to ensure the best results.
• If you experience nausea, taking the capsule with a light snack may help.
• Avoid taking antacids or dairy products within 2 hours of Erdosteine to prevent interaction.
• Stay well-hydrated during your treatment.
• Contact your doctor if you experience any persistent side effects.