EROBE SYP 120ML

Erythromycin in the Erythromycin, Bromhexine Syrup/Suspension combination primarily exerts its antibacterial effect by binding to the 50S subunit of bacterial ribosomes, thereby inhibiting protein synthesis in susceptible bacteria. This binding interferes with the translocation step, preventing the proper alignment of the ribosome complex and halting the production of essential proteins required for bacterial growth and survival. Bromhexine, on the other hand, acts as an expectorant by reducing the viscosity of mucus in the respiratory tract. It enhances the clearance of mucus by stimulating the production and secretion of thinner, more fluid mucus, which aids in the removal of respiratory secretions and facilitates improved airway clearance.

Erythromycin, Bromhexine

Macrolide, Expectorant.

Suspension

The following are the uses of Erythromycin, Bromhexine Syrup/Suspension:

• Used for treating respiratory tract infections, reducing phlegm and clearing mucus
• Used for easing coughing and soothing irritated throats
• Used for managing acute and chronic bronchitis, pneumonia, and other lower respiratory tract infections
• Used for reducing inflammation in the airways
• Used for preventing the progression of respiratory infections
• Used for aiding in the recovery from respiratory illnesses
• Used for relieving chest congestion
• Used for supporting overall respiratory health

In the case of an overdose of Erythromycin, symptoms may include gastrointestinal issues such as nausea, vomiting, and diarrhea. It can also lead to hearing loss and balance disorders. For Bromhexine Syrup/Suspension overdose, expect increased side effects such as mild gastrointestinal upset, skin rash, and rarely, liver damage. Prompt medical attention is advised for both cases, and treatment may involve managing symptoms and providing supportive care.

In the case of a missed dose of Erythromycin, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. For Bromhexine Syrup/Suspension, if a dose is missed, take it as soon as possible, but if it is nearly time for your next dose, skip the missed dose and resume your regular dosing schedule. It is crucial not to double the dose to compensate for a missed one.

To administer Erythromycin and Bromhexine Syrup/Suspension, shake the bottle well, measure the prescribed dose with a measuring cup or oral syringe, and take it orally as directed by your healthcare professional, typically twice a day, with or without food, ensuring you complete the full course as prescribed.

Here are the conditions and situations when Erythromycin, Bromhexine Syrup/Suspension should not be used:

• Not recommended for individuals with a known allergy to Erythromycin or Bromhexine or any other macrolide antibiotics.
• Should not be used in patients with a history of severe liver or kidney disease.
• Contraindicated in patients with a history of gastrointestinal blockage or perforation.
• Not suitable for infants under 6 months of age due to potential side effects.
• Should be avoided during pregnancy, especially in the first trimester, unless the potential benefits outweigh the risks.
• Not recommended for breastfeeding mothers as it may pass into breast milk and cause side effects in the nursing infant.
• Avoid using this medication if you have a history of prolonged QT interval or heart rhythm disorders.
• Do not use if you have ever had jaundice or liver problems caused by erythromycin.

The side effects of Erythromycin, Bromhexine Syrup/Suspension may include:

• Nausea and vomiting
• Stomach pain or cramps
• Diarrhea
• Dizziness
• Hearing loss or ringing in the ears (tinnitus)
• Skin rash or itching
• Fatigue and weakness
• Allergic reactions (such as hives, difficulty breathing)

Following are the precautions and warnings for Erythromycin, Bromhexine Syrup/Suspension:

• This medication should not be used in patients with a known allergy to Erythromycin, Bromhexine, or similar antibiotics.
• Patients with liver or kidney disease should use this medication with caution and under medical supervision as it may require dosage adjustments.
• It is important to complete the full course of medication as prescribed, even if symptoms improve, to ensure the infection is completely treated.
• Avoid consuming grapefruit or grapefruit juice while taking this medication as it can affect the medication's effectiveness.
• This medication may cause dizziness or blurred vision, so patients should avoid driving or operating heavy machinery until they know how the medication affects them.
• Pregnant or breastfeeding women should consult their doctor before using this medication as it may have potential risks to the fetus or infant.
• Elderly patients may be more sensitive to the side effects of this medication, so close monitoring is recommended.

Following are the drug interactions for Erythromycin, Bromhexine Syrup/Suspension:

• Erythromycin may interact with other macrolide antibiotics, increasing the risk of cardiac side effects, including QT prolongation.
• It can inhibit the metabolism of various drugs, including Theophylline, Ciclosporin, and certain statins, leading to increased levels of these medications in the body.
• Concomitant use with Ergotamine or other ergot derivatives may result in ergot toxicity.
• Bromhexine can increase the absorption of other medications, such as Amoxicillin, when taken together.
• Avoid using with other cough suppressants or expectorants, as it may lead to excessive coughing suppression.
• Anticoagulants like Warfarin may have their effects enhanced, requiring close monitoring of coagulation parameters.
• May increase the risk of side effects when taken with other medications that can affect the heart, such as certain antiarrhythmic drugs.

Following are the food interactions for Erythromycin, Bromhexine Syrup/Suspension:

• Alcohol consumption should be avoided as it can increase the risk of side effects such as stomach upset and liver problems.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of Erythromycin, leading to increased drug levels in the body and potential side effects.
• High-fat meals can slightly delay the absorption of Bromhexine, but it is generally well-tolerated with food.
• Avoid caffeine and energy drinks as they may interact with the medication and cause increased heart rate and nervousness.
• Avoid eating large quantities of dairy products, as calcium-rich foods can potentially decrease the absorption of Erythromycin.
• Consuming a healthy diet with plenty of fluids can help maintain hydration and support the respiratory system while taking Bromhexine.
• Certain fruit juices, especially those high in acidity like orange juice, may irritate the stomach when taken with Erythromycin.
• Avoid any known food allergies, as the medication may not be effective if an allergic reaction occurs.

Erythromycin and Bromhexine Syrup/Suspension should be stored in a cool and dry place, preferably at room temperature, ensuring it is kept away from direct sunlight and moisture. It is crucial to store the medication in its original container, tightly sealed, to maintain its integrity and prevent contamination. Avoid extreme temperatures by not placing it near heat sources or in the bathroom, as this can impact its effectiveness. Dispose of any unused or expired syrup responsibly; do not flush it or pour it down the drain. Consult a pharmacist or healthcare professional for guidance on appropriate disposal methods, and always keep medications out of the reach of children to prevent accidental consumption.

Following are the quick tips for Erythromycin, Bromhexine Syrup/Suspension:

• Consult your doctor or pharmacist for dosage instructions specific to your condition.
• Ensure the medication is well-shaken before each use.
• Administer the syrup/suspension with a measuring cup or syringe for accurate dosing.
• Avoid mixing with other medications unless advised by your healthcare provider.
• Store the medication at room temperature, away from direct sunlight and moisture.
• Do not use if the syrup/suspension changes color or develops an unusual odor.
• Regularly monitor your health and report any persistent side effects to your doctor.