EROGLOBIN SYP 120ML

Ferric ammonium citrate, when administered orally in syrup or suspension form, acts as a source of ferric iron (Fe3+), which is essential for the formation of hemoglobin in red blood cells. The mechanism of action involves the reduction of ferric iron to its ferrous (Fe2+) state in the acidic environment of the stomach. This reduced form is more easily absorbed in the intestine, where it binds to transferrin, a protein that transports iron in the bloodstream. Once absorbed, iron is utilized in various metabolic processes, primarily in the synthesis of hemoglobin. It becomes incorporated into the hemoglobin molecule, facilitating oxygen transport to tissues and supporting overall cellular respiration and energy production.

Ferric ammonium citrate

Oral iron supplement

Suspension

The following are the uses of Ferric ammonium citrate Syrup/Suspension:

• Used for treating and preventing iron deficiency anemia
• Used as a dietary supplement to manage nutritional deficiencies
• Used to improve iron levels in the body, especially during pregnancy or with certain medical conditions
• Used for enhancing athletic performance and energy levels in individuals with iron deficiency
• Used in food fortification to enrich products with iron
• Used to enhance the color and stability of certain foods and beverages
• Used in the treatment of certain gastrointestinal disorders to improve iron absorption

In the case of an overdose of Ferric ammonium citrate Syrup/Suspension, the primary concern is the high iron content. Symptoms may include nausea, vomiting, abdominal pain, and gastrointestinal bleeding. In severe cases, organ damage, particularly to the liver, can occur. Prompt medical attention is necessary, and treatment may involve managing symptoms, monitoring vital signs, and providing supportive care to minimize the impact of the overdose.

In the case of a missed dose of Ferric ammonium citrate Syrup/Suspension, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication regimen.

To administer Ferric ammonium citrate Syrup/Suspension, shake the bottle thoroughly, measure the prescribed dose with an accurate measuring device, and administer it orally, following the dosage instructions provided by your healthcare professional, typically taken once or twice daily, either with or without meals as directed.

Here are the conditions or situations when Ferric ammonium citrate Syrup/Suspension should not be used:

• Not suitable for individuals with known allergies or hypersensitivity to any of the components, including ferric compounds or citrates.
• Contraindicated in patients with hemochromatosis, a condition where the body stores too much iron.
• Should be avoided in cases of acute iron poisoning or iron overload.
• Not recommended for individuals with certain types of anemia, such as sideroblastic anemia or thalassemia.
• Should not be used in patients with liver disease or impaired liver function.
• Not suitable for individuals with gastrointestinal conditions that affect iron absorption, such as inflammatory bowel disease.
• Avoid use in patients with a history of gastrointestinal bleeding or those at risk of bleeding disorders.
• Contraindicated in patients with a known or suspected iron metabolism disorder, such as hereditary hemochromatosis or porphyria cutanea tarda.

The side effects of Ferric ammonium citrate Syrup/Suspension may include:

• Constipation
• Darkening of stools
• Abdominal pain or discomfort
• Nausea and vomiting
• Diarrhea
• Blackening of teeth (when in contact with teeth)
• Temporary staining of the skin or clothing

Following are the precautions and warnings for Ferric Ammonium Citrate Syrup/Suspension:

• This medication should not be used in patients with known hypersensitivity or allergy to any of its components, including ferric compounds.
• Patients with gastrointestinal disorders such as ulcerative colitis, enteritis, or gastritis should use this medication with caution as it may exacerbate these conditions.
• It may cause gastrointestinal side effects such as nausea, vomiting, or constipation. Discontinue use and consult a doctor if these symptoms persist or worsen.
• May lead to iron overload or iron toxicity if used in excess or for prolonged periods. Regular monitoring of iron levels is recommended.
• Not recommended for use in children under 6 years of age unless prescribed by a healthcare professional.
• Patients with a history of kidney disease or those taking other medications should inform their doctor to ensure safe usage.
• Pregnant and breastfeeding women should consult their healthcare provider before using this medication as it may affect fetal development and pass into breast milk.

Following are the drug interactions for Ferric ammonium citrate Syrup/Suspension:

• Can decrease the absorption of tetracycline antibiotics, such as doxycycline, leading to reduced effectiveness of the antibiotic.
• Iron supplements may reduce the absorption of levothyroxine, a thyroid medication, requiring dose adjustments.
• Concomitant use with chloramphenicol, an antibiotic, may decrease the absorption of both drugs.
• Ferric ammonium citrate can reduce the efficacy of bisphosphonates, such as alendronate, used for osteoporosis.
• It may interfere with the absorption of certain medications like quinolones (ciprofloxacin) and ACE inhibitors (captopril).
• Taking Ferric ammonium citrate with certain antacids containing calcium or magnesium can decrease iron absorption.
• This medication may reduce the effectiveness of levodopa, a Parkinson's disease treatment, due to its chelating properties.

Following are the food interactions for Ferric ammonium citrate Syrup/Suspension:

• Avoid consuming tea or coffee with meals when taking this medication, as tannins in these beverages may interfere with iron absorption.
• Vitamin C-rich foods like citrus fruits, tomatoes, and broccoli can enhance iron absorption, so consider pairing these foods with your dose.
• Dairy products like milk, cheese, and yogurt can hinder iron absorption. Avoid consuming them simultaneously with your iron supplement.
• Whole grains and high-fiber foods may reduce iron absorption. Try to consume iron-rich foods or supplements separately from high-fiber meals.
• Calcium-rich foods such as spinach, almonds, and fortified cereals can decrease iron absorption. Separate calcium-rich meals from your iron medication.
• Certain proteins found in foods like eggs, meat, and fish can inhibit iron absorption. It's best to take the medication on an empty stomach or with a light snack.
• Avoid alcohol consumption while taking this medication, as it may interfere with iron absorption and increase the risk of gastrointestinal side effects.

Ferric ammonium citrate Syrup/Suspension should be stored in a cool and dry location, preferably at room temperature, ensuring protection from direct sunlight and moisture. Maintain the medication in its original container, tightly sealed, to prevent contamination. Avoid storage in bathrooms or near heat-emitting appliances to prevent temperature-induced degradation. Prior to use, verify the expiration date on the packaging, and dispose of any unused or expired syrup responsibly. For safe disposal methods, consult your pharmacist or healthcare provider, and refrain from flushing or pouring the medication down the drain. Additionally, keep the medication out of children's reach to prevent accidental ingestion.

Following are the quick tips for Ferric ammonium citrate Syrup/Suspension:

• Always follow the dosage instructions provided by your doctor or pharmacist.
• Ensure you shake the bottle well before each use to maintain consistency.
• Administer the syrup with a glass of water for better absorption.
• Maintain a consistent schedule for taking the syrup, preferably at the same time daily.
• Consider taking it with food if stomach irritation occurs.
• Store the medication in a safe place, away from children's reach.
• Regularly monitor your iron levels and consult your doctor for adjustments if needed.