ERYTHROCIN DROP 30ML

Erythromycin drop, when administered topically to the eye, exerts its antimicrobial effect by inhibiting protein synthesis in susceptible bacteria. It primarily targets the 50S subunit of the bacterial ribosome, preventing the translocation of aminoacyl-tRNA and causing an incorrect reading of the genetic code. This interference with protein synthesis ultimately leads to the cessation of bacterial growth and replication. Erythromycin is particularly effective against a range of gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae, making it useful in treating various ocular infections caused by these microorganisms.

Erythromycin

Macrolide antibiotic

Drop

The following are the uses of Erythromycin Drop:

• Used for treating bacterial eye infections, such as conjunctivitis.
• Used for preventing eye infections after minor eye surgery or injuries.
• Used for reducing eye inflammation and irritation.
• Used for controlling bacterial growth on the eye surface.
• Used for improving eye comfort and reducing redness.
• Used for preventing the spread of eye infections to others.
• Used for supporting eye healing after infections.

In the case of an overdose of Erythromycin Drops, several adverse effects may occur, including gastrointestinal symptoms such as nausea, vomiting, and diarrhea. These symptoms can be accompanied by more severe reactions like hearing loss, tinnitus, and potentially dangerous cardiac arrhythmias. Prompt medical intervention is necessary to manage these symptoms and prevent further complications, especially in cases where the overdose is significant or combined with other medications.

In the case of a missed dose of Erythromycin Drops, it is important to administer the medication as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not administer a double dose to make up for the missed one. If you miss multiple doses, contact your healthcare provider for advice on how to proceed, as they may recommend adjusting the dosage or provide specific instructions to ensure the medication's effectiveness.

To administer Erythromycin Drops, gently tilt your head back, pull the lower eyelid down to create a pocket, and hold the dropper tip above the eye; release one drop into the pocket, then close your eye gently to allow the drop to absorb.

Following are the conditions/situations when Erythromycin Eye Drops should not be used:

• Should not be used if you have a known allergy or hypersensitivity to Erythromycin or any other macrolide antibiotics.
• Not suitable for individuals who have shown previous allergic reactions to eye drops or similar medications.
• Avoid using if you have or suspect a fungal or viral infection in the eye(s), as Erythromycin is not effective against these types of infections.
• Do not use if you have or suspect a corneal ulcer or other severe eye infections without consulting an eye specialist.
• Contraindicated for individuals with a history of severe liver or kidney disease.
• Not recommended for infants, especially newborns, unless prescribed by a pediatrician.
• Should not be used if the eye drop solution changes color or becomes cloudy.
• Discontinue use and consult a doctor if you experience severe eye irritation, increased redness, or swelling after using the drops.

The side effects of Erythromycin Eye Drops may include:

• Stinging or burning sensation in the eyes.
• Itching or redness of the eyes.
• Watery eyes or increased tearing.
• Blurred vision or temporary changes in vision.
• Eye discharge or crusting.
• Mild skin rash or irritation around the eyes.
• Dry eyes or a feeling of grittiness in the eyes.
• Allergic reactions, such as swelling of the eyelids or face.

Following are the precautions and warnings for Erythromycin Eye Drop:

• Avoid using if you have a known allergy to Erythromycin or any other ingredients in the eye drop.
• If you wear contact lenses, remove them before application and wait for at least 15 minutes after using the drop before reinserting the lenses.
• Do not touch the dropper tip to any surface, including your eye, to avoid contamination.
• Do not use the eye drop if the solution changes color or becomes cloudy.
• Discontinue use and consult a doctor if you experience severe eye irritation, pain, or vision changes.
• Keep out of reach of children. Store at room temperature, away from direct sunlight and moisture.
• Inform your healthcare provider about any other eye medications or medical conditions before using Erythromycin eye drops.

Following are the drug interactions for Erythromycin Drop:

• Concomitant use with other macrolide antibiotics (e.g., clarithromycin, azithromycin) may increase the risk of cardiovascular side effects and hearing impairment.
• Erythromycin can inhibit the metabolism of drugs metabolized by the cytochrome P450 system, such as calcium channel blockers, statins, and benzodiazepines, leading to increased drug levels and potential toxicity.
• Theophylline levels may be increased when used with Erythromycin, requiring dosage adjustments.
• Anticoagulants like warfarin may have their effect enhanced, requiring close monitoring of coagulation parameters.
• Drugs that induce the cytochrome P450 system (e.g., rifampicin, phenytoin) can reduce the effectiveness of Erythromycin.
• Co-administration with colchicine may increase colchicine toxicity, and dosage adjustments are necessary.
• Erythromycin may increase the risk of arrhythmias when used with certain antiarrhythmic medications (e.g., amiodarone, quinidine).

Following are the food interactions for Erythromycin Drops:

• Avoid consuming grapefruit or grapefruit juice as they can increase the levels of Erythromycin in the blood, potentially leading to increased side effects.
• Alcohol consumption should be avoided as it may enhance the side effects like nausea, dizziness, and stomach discomfort.
• Dairy products like milk, cheese, and yogurt may reduce the absorption of Erythromycin, so consider taking the medication at least 2 hours before or after consuming dairy.
• High-fat meals might delay the absorption of Erythromycin, so it's best to use the drops on an empty stomach or at least 30 minutes before a meal.
• Avoid carbonated drinks as they can irritate the stomach and potentially reduce the effectiveness of the medication.
• Caffeinated beverages like coffee and tea might increase stomach acid production, which could interfere with the absorption of Erythromycin.
• Spicy foods should be consumed with caution as they can irritate the digestive system, especially if you have a stomach or intestinal issue.
• Always follow the dosage instructions provided by your healthcare professional to ensure the best effectiveness of Erythromycin drops.

Erythromycin Drops should be stored in a cool and dry place, preferably at room temperature, ensuring protection from direct sunlight and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial not to expose the medication to extreme temperatures, so avoid storage in bathrooms or near heat-emitting appliances. Regularly check the expiration date, and if the drops are no longer needed or have expired, proper disposal is essential. Do not dispose of by flushing or pouring down the drain; consult a pharmacist or healthcare professional for guidance on appropriate disposal methods to ensure environmental safety. Keep the medication securely stored away from children to prevent accidental ingestion.

Following are the quick tips for Erythromycin Drop:

• Wash your hands thoroughly before and after applying the drops to maintain hygiene.
• Tilt your head back slightly and gently pull down the lower eyelid to create a small pocket.
• Hold the dropper close to the eye without touching it to avoid contamination.
• Squeeze the prescribed number of drops into the lower eyelid pocket.
• Close your eyes gently and tilt your head forward to allow the drops to spread.
• Avoid blinking rapidly; instead, gently press the corner of your eye with your finger for a few minutes.
• If using other eye medications, wait at least 5 minutes before applying the next medication.
• Store the drops at room temperature, away from direct sunlight and moisture.