Estranor (2/0.5mg) 21 Tablets

Estranor (2/0.5mg) 21 Tablets

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  • Manufacturer Saffron Pharmaceuticals (Pvt.) Ltd.
  • Generic Name Estradiol Valerate, Norgestrel

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Description

    Estradiol Valerate 2mg acts as a powerful hormone that mimics the action of estrogen in the female body. Administered orally, it is quickly absorbed and binds to estrogen receptors in the reproductive system. By doing so, it suppresses the secretion of follicle-stimulating and luteinizing hormones, which are responsible for ovulation and fertility. As a result, it works to effectively prevent pregnancy and reduces symptoms associated with menopause, such as hot flashes and vaginal dryness. Meanwhile, Norgestrel 0.5mg acts as a progesterone-like hormone that interferes with the reproductive process. It blocks the secretion of follicle-stimulating hormone and luteinizing hormone, preventing regular ovulation and disrupting the uterine lining. This intervention thins the lining, making it less conducive for implantation. Moreover, it influences the cervical mucus, making it thicker and less favorable for sperm mobility, further contributing to its contraceptive effects. Both medications in combination provide a powerful hormonal mechanism of action that not only prevents pregnancy but also relieves symptomatic women of menopause.

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  • Ingredients

    Estradiol Valerate, Norgestrel
  • Drug Class

    Contraceptives

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  • Dosage Form

    Tablet

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  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Treat estrogen deficiency in women who have passed through the menopausal stage
    • Treatment of symptoms occurring during the menopause and peri-menopause
    • Treatment of female hypogonadism
    • Prevention of osteoporosis in post-menopausal women
    • Norgestrel

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  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Estradiol Valerate 2mg
    • Amount to take depends on many factors, including whether you're using it for hormone replacement therapy (HRT) or contraception, as well as your individual physiology.
    • For HRT, the typical starting dose is 2-4 mg/day. It can be administered via several routes, including oral, topical, or vaginal. For example, a typical pill contains 1 mg of estradiol valerate, which is considered bio-equivalent to 2 mg of injected estrogen.
    • For contraception, a typical dose of Estradiol Valerate 2mg typically used in conjunction with Norgestrel 0.5 mg for contraception is often administered as a single combined pill taken orally. This pill typically contains 2-3 mg of estradiol valerate and 0.5 mg of norgestrel.
    • Norgestrel 0.5 mg
    • Norgestrel is a progestin, typically used in combination with an estrogen for contraceptive pills.
    • For contraception, it is typically used in a dose of 0.5 mg or 1 mg, depending on the formulation. This dose may vary depending on the country and the brand of the contraceptive pill. The combination of Norgestrel with Estradiol valerate is typically used in a ratio of 1-20, implying that Norgestrel constitutes 0.5% of the formulation.

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  • In case of Overdose

    An overdose of Estradiol Valerate 2mg, Norgestrel 0.5mg, may cause a range of symptoms, including nausea and vomiting, headaches, sweating, rapid or irregular heartbeat, facial flushing, musculoskeletal symptoms such as pain in the waist, lower back, legs, or tension headaches, mood changes or depressed mood, confusion, and labored breathing. These symptoms may vary in severity, and it is essential to seek immediate emergency help if you suspect someone has experienced an overdose. You can do this by calling your local emergency services or poison control center. It is important to note that these symptoms may occur as a result of other medical conditions or medications, so it is always important to seek professional medical advice for any concerning symptoms or changes in your health.

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  • Missed Dose

    If you have missed a dose of Estradiol Valerate 2mg and Norgestrel 0.5mg, here's what you should do. It is advised to take the missed dose as soon as possible. However, if it is almost time for your next scheduled dose, it is recommended to skip the missed dose and take the next dose at the regular time to avoid taking a double dose. It is important to not take a double dose as it may lead to side effects. If you have any concerns, it is best to speak with your healthcare provider or consult the instructions that accompanied the medication.

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  • How To Use

    Before starting to take Estradiol Valerate 2mg and Norgestrel 0.5mg, it is crucial to understand the correct procedure to take them effectively and safely. Reading the medication guide provided by your doctor or pharmacist is the first step. This guide will educate you about the drugs' purposes, possible side effects, and safety precautions. The next step is to make sure you are familiar with the correct dosage. Estradiol Valerate 2mg is typically taken once daily, within a dosage range of 1 to 2 mg. Norgestrel 0.5mg is also usually taken once daily, with a typical dosage range of between 0.05 and 0.1 mg. However, your doctor will determine the precise dosage you should take based on your specific needs.It is essential to discuss any concerns or questions you may have regarding the medication with your doctor or pharmacist. They can provide additional guidance and support regarding your treatment plan. Take the tablets consistently, with or without food, and at the same time each day. This helps maintain a consistent level of medication in your body, ensuring its effectiveness. Store the medication properly, in a cool, dry place away from direct heat or light. Monitoring your body and overall health is also essential; regular checkups and lab tests will help keep track of any changes and ensure your health. Following these steps and instructions provided by the doctor will help ensure the drugs are taken properly and effectively.

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  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • If you are pregnant • Taking this medication while pregnant can increase the risk of miscarriage, premature birth, and other complications.
    • If you are breastfeeding • This medication can pass into breast milk and may harm a nursing infant.
    • If you have a history of certain cancers • This medication is typically not recommended for individuals with a history of certain cancers.
    • If you have a history of certain blood clots • This medication may increase the risk of blood clots, particularly in individuals with a personal or family history of blood clots.
    • When undergoing an MRI • You should not undergo an MRI if you are taking this medication.
    • It is important to provide your doctor with a full medical history.

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  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Headaches
    • Blood clots
    • Weight gain
    • High blood pressure
    • Nausea
    • Breast tenderness
    • Depression
    • Mood swings
    • Vaginal irritation
    • Vulvar itching and dryness

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  • Precautions & Warnings

    The warnings and precautions associated with Estradiol Valerate and Norgestrel include the following. Before taking medication, tell your doctor or pharmacist if you are allergic to it or to other progestins such as norethindrone, or if you have any other allergies. This product may contain inactive ingredients such as tartrazine, which can cause allergic reactions or other problems. Consult your doctor or pharmacist if you have an abnormal breast exam, cancer (especially breast cancer), diabetes, depression, severe headaches or migraines, a history of jaundice during pregnancy or hormonal birth control, liver disease including tumors, or unexplained vaginal bleeding. This drug may cause dizziness, and alcohol or marijuana can increase this effect, so it's advisable to limit alcoholic beverages. Before having surgery, inform your doctor or dentist about all the products you use, including prescription, nonprescription drugs, and herbal products.

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  • Drug Interactions

    The drug interactions with estradiol valerate and norgestrel include:

    • Antibiotics (e.g., rifampin) – Can reduce hormonal contraceptive effectiveness.
    • Anticoagulants (e.g., warfarin) – Can be affected by hormonal changes.

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  • Food Interactions

    For Ethinyloestradiol and Ethisterone, food interactions that should be considered are:

    • Taking with food may help improve absorption.
    • Avoid taking with St. John's Wort as it may reduce effectiveness.

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  • Storage/Disposal

    Storing Estradiol Valerate 2mg and Norgestrel 0.5mg require certain standards to be met in order to preserve the efficacy and safety of the medications.Estranor (2/0.5 mg) tablets should be stored at room temperature, away from moisture and direct sunlight. Keep the tablets in their original packaging and out of reach of children. Any unused or expired Estranor tablets should be disposed of properly.



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