ETHIFRIN EYE DROPS 5ML

Phenylephrine, a selective alpha-1 adrenergic receptor agonist, exerts its primary effect by stimulating postsynaptic alpha-1 receptors in the arterioles of the nasal mucosa. This stimulation leads to vasoconstriction, resulting in reduced blood flow to the nasal passages. The direct action on the alpha-1 receptors causes a narrowing of the blood vessels, which helps to alleviate nasal congestion. By promoting vasoconstriction, Phenylephrine reduces swelling and congestion in the nasal tissues, thereby improving nasal airflow and providing relief from nasal congestion associated with various conditions such as the common cold, allergies, or sinusitis.

Alpha-adrenergic agonist

Drop

The following are the uses of Phenylephrine Drop:

• Used for temporarily relieving nasal congestion due to the common cold, hay fever, or other upper respiratory allergies.
• Used for reducing swelling in the nose and sinuses, providing relief from stuffy nose and sinus pressure.
• Used for helping patients breathe more easily, especially when suffering from nasal congestion.
• Used for treating symptoms like a runny or itchy nose, sneezing, and nasal discomfort.
• Used for promoting sinus drainage and reducing facial pain associated with sinus congestion.
• Used for providing temporary relief, allowing better airflow and comfort during nasal congestion episodes.
• Used for both adults and children, under medical guidance, to alleviate nasal discomfort.

In the case of an overdose of Phenylephrine Drops, it is important to recognize the potential symptoms such as severe headache, rapid heartbeat, and anxiety. Promptly seek medical advice by contacting a healthcare professional or poison control center. They will provide guidance on the necessary steps to take, which may include inducing vomiting or administering activated charcoal to prevent further absorption. Quick action is essential to minimize any adverse effects.

In the case of a missed dose of Phenylephrine Drops, it is generally advised to administer the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss several doses, consult your healthcare professional for guidance on how to safely resume the medication without affecting its overall effectiveness.

To administer Phenylephrine Drops, gently tilt your head back, instill the prescribed number of drops into the affected eye(s) by pulling down the lower eyelid, and then close your eyes for 1-2 minutes to allow the medication to be absorbed.

Following are the conditions/situations when Phenylephrine Drops should not be used:

• Should not be used if the patient has an allergy to phenylephrine or any other decongestant medications.
• Contraindicated in patients with high blood pressure (hypertension) that is not controlled.
• Not suitable for individuals with severe heart disease, including irregular heartbeat or heart rhythm disorders.
• Avoid using these drops if you have recently had a heart attack.
• Should not be used in patients with narrow-angle glaucoma.
• Contraindicated in individuals with an overactive thyroid (hyperthyroidism).
• Not recommended for those with severe diabetes, especially if blood sugar is not well-controlled.
• Avoid using these drops if you have a blockage or narrowing of the stomach or intestines.
• Should not be used in patients with a history of urinary retention or difficulty urinating.
• Do not use if you have a tumor on the adrenal gland (pheochromocytoma).
• Contraindicated in individuals with severe kidney disease.

The side effects of Phenylephrine Eye Drops may include:

• Eye redness or irritation.
• Mild burning or stinging in the eye.
• Blurred vision temporarily.
• Headache or dizziness.
• Increased eye pressure (especially in glaucoma patients).
• Soreness or discomfort in the eye.
• Sensitivity to light.

Following are the precautions and warnings for Phenylephrine Drops:

• Not recommended for individuals with narrow-angle glaucoma, severe cardiovascular disease, or those who have recently had a heart attack.
• People with diabetes, heart disease, high blood pressure, thyroid disease, or prostate problems should use with caution and under medical supervision.
• May cause dizziness or drowsiness; patients should avoid driving or operating heavy machinery until they know how the medication affects them.
• Avoid using other decongestants or stimulants while taking Phenylephrine to prevent excessive stimulation and potential side effects.
• Do not exceed the recommended dosage, as it may lead to serious side effects, including rapid heart rate and high blood pressure.
• Discontinue use and seek medical attention if symptoms worsen, persist for more than a few days, or if you experience severe side effects such as chest pain, irregular heartbeat, or severe headache.
• Keep out of reach of children. In case of accidental ingestion, seek immediate medical help.
• Consult a healthcare professional before using this medication if you are taking any other medications or have any underlying medical conditions.

Following are the drug interactions for Phenylephrine Drop:

• It can interact with monoamine oxidase inhibitors (MAOIs), potentially leading to a rise in blood pressure.
• May reduce the effectiveness of beta-blockers and certain antidepressants.
• Antihypertensive medications can be affected, causing decreased blood pressure control.
• Phenylephrine may increase the effects of other sympathomimetic agents, raising blood pressure and heart rate.
• Concomitant use with tricyclic antidepressants can result in increased cardiovascular side effects.
• The effectiveness of alpha-blockers may be reduced when used together.
• It can also interact with certain cough and cold medications containing similar active ingredients, potentially causing excessive stimulation.

Following are the food interactions to consider with Phenylephrine Drops:

• Avoid consuming alcohol as it can increase the risk of side effects, especially when taken in larger quantities.
• Caffeine-rich beverages like coffee, tea, and energy drinks should be limited as they may constrict blood vessels and potentially increase blood pressure.
• Grapefruit and grapefruit juice should be avoided as they can interfere with the metabolism of Phenylephrine, leading to higher blood levels and potential side effects.
• Spicy foods can potentially increase blood flow to the nasal passages and may interact with the decongestant effect of Phenylephrine.
• Hot and pungent foods like chili peppers might cause nasal irritation and potentially counteract the decongestant action.
• Chocolate contains compounds that can act as mild stimulants and may interact with Phenylephrine's effects on the blood vessels.
• Dairy products can sometimes increase mucus production, which might be counterproductive when using Phenylephrine for congestion relief.
• It's advisable to maintain a balanced diet, ensuring adequate hydration, as proper hydration can aid in thinning mucus and facilitating its removal.

Phenylephrine Drops should be stored in a cool, dry place, preferably at room temperature between 68°F and 77°F (20°C and 25°C). Protect the medication from excessive heat, direct sunlight, and moisture. Keep the drops in their original container, tightly sealed, to maintain their integrity and prevent contamination. Always check the expiration date, and do not use the drops if they have expired. For disposal, do not pour them down the sink or toilet; instead, contact your pharmacist or local waste disposal company for guidance on how to safely discard the medication. Keep the drops out of the reach of children and pets to prevent accidental ingestion.

Following are the quick tips for Phenylephrine Drops:

• Consult your healthcare provider before using the drops, especially if you have underlying medical conditions.
• Wash your hands thoroughly before administering the drops to ensure hygiene.
• Tilt your head back slightly and instill the prescribed number of drops into the affected eye(s).
• Close your eyes gently and apply light pressure to the inner corner of the eye(s) to minimize drainage.
• Avoid touching the dropper tip to any surface to prevent contamination.
• Store the drops at room temperature, away from direct sunlight and moisture.
• Dispose of any unused or expired medication safely.