Exelon (1.5mg) 28 Capsules

Rivastigmine, a potent acetylcholinesterase inhibitor, exerts its therapeutic effects by slowing down the breakdown of acetylcholine in the brain. It selectively binds to and inhibits both butyrylcholinesterase and acetylcholinesterase enzymes, resulting in increased acetylcholine levels. This enhanced acetylcholine concentration is particularly beneficial in the central nervous system, where it plays a crucial role in improving cognitive function and memory. The primary mechanism of action of Rivastigmine is attributed to its ability to counteract the cholinergic deficit observed in conditions like Alzheimer's disease and dementia, thereby promoting improved cognitive performance and potentially slowing down the progression of these neurodegenerative disorders.

Cholinesterase inhibitor.

Capsule

The following are the uses of Rivastigmine 5mg Capsule:

• Used for treating mild to moderate Alzheimer's disease.
• Used to improve cognitive function and memory.
• Used to enhance daily living activities in dementia patients.
• Used to manage symptoms of dementia related to Parkinson's disease.
• Used to slow down the progression of cognitive decline.
• Used for improving attention and concentration.
• Used to reduce behavioral disturbances associated with dementia.
• Used to potentially delay the need for residential care.

In the case of an overdose of Rivastigmine 5mg Capsules, individuals may experience severe symptoms such as nausea, vomiting, slow heart rate, difficulty breathing, and fainting. Promptly seek medical assistance if you suspect an overdose. Treatment involves managing these symptoms and may include gastric lavage to remove the medication from the stomach, as well as supportive care to stabilize vital signs. It is crucial to contact a healthcare professional or a poison control center for guidance and immediate care.

In the case of a missed dose of Rivastigmine 5mg Capsule, it is generally advised to take the medication as soon as you remember. However, if it's almost time for your next scheduled dose, it's best to skip the missed dose and continue with your regular dosing schedule. Avoid taking extra capsules to make up for a missed dose, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track with your medication regimen. It's important to maintain consistency in taking this medication as prescribed.

To take Rivastigmine 5mg Capsule, swallow the capsule whole with a full glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, typically once or twice daily.

Following are the conditions or situations when Rivastigmine 5mg Capsule should not be taken:

• Do not take if you have a known allergy or hypersensitivity to Rivastigmine or other similar medications.
• Not suitable for individuals with certain gastrointestinal conditions such as ulcerative colitis, gastrointestinal bleeding, or those with a history of peptic ulcer disease.
• Should not be used in individuals with severe liver impairment as it can lead to increased side effects.
• Contraindicated in patients with severe kidney disease or end-stage renal disease.
• Not recommended for individuals with a history of seizures or epilepsy.
• Avoid using Rivastigmine if you have a respiratory condition like asthma or chronic obstructive pulmonary disease (COPD).
• Do not administer to individuals with a history of cardiac arrhythmias or heart block.

The side effects of Rivastigmine 5mg Capsule may include:

• Nausea and vomiting
• Diarrhea
• Abdominal pain
• Loss of appetite
• Weight loss
• Dizziness
• Headaches
• Increased sweating

Following are the precautions and warnings for Rivastigmine 5mg Capsule:

• This medication should not be started in patients with severe liver impairment, and dosage adjustments are necessary for patients with mild to moderate liver impairment.
• Patients with a history of peptic ulcers or gastrointestinal bleeding should be closely monitored as this drug may increase the risk of gastrointestinal bleeding.
• It may cause weight loss, and regular monitoring of weight is recommended, especially in underweight patients.
• Not recommended for individuals with a history of seizures or those with conditions that may increase the risk of seizures.
• Caution is advised when using Rivastigmine in patients with cardiac conduction disorders or sick sinus syndrome, as it may affect heart rate.
• Patients with asthma or chronic obstructive pulmonary disease (COPD) should be monitored closely as it may exacerbate respiratory symptoms.
• Rivastigmine may cause fainting or dizziness, so patients should avoid driving or operating heavy machinery until they know how the medication affects them.

Following are the drug interactions for Rivastigmine 5mg Capsule:

• Concomitant use with cholinesterase inhibitors or cholinergic agonists (e.g., pyridostigmine, neostigmine) may result in increased cholinergic activity and potential adverse effects.
• Central nervous system (CNS) depressants, such as benzodiazepines, opioids, or antipsychotics, can potentiate the cholinomimetic effects of rivastigmine, leading to increased sedation and respiratory depression.
• The use of anticholinergic medications (e.g., tricyclic antidepressants, antihistamines) may counteract the therapeutic effects of rivastigmine.
• Rivastigmine may increase the bioavailability of certain drugs metabolized by the liver, including some beta-blockers, calcium channel blockers, and anticonvulsants.
• Caution is advised when combining rivastigmine with medications that affect gastrointestinal motility, as it may alter the absorption of these drugs.
• Rivastigmine may decrease the effectiveness of anticholinergic bronchodilators used in respiratory conditions.
• Care should be taken when using rivastigmine with other drugs that increase gastric acid secretion, as it may enhance the risk of gastrointestinal side effects.

Following are the food interactions for Rivastigmine 5mg Capsule:

• Alcohol consumption should be avoided as it may increase the risk of side effects, particularly nausea and dizziness.
• Grapefruit and grapefruit juice should be consumed with caution as they can influence the drug's metabolism, potentially altering its effectiveness.
• Fatty meals may delay the absorption of Rivastigmine, so it is advisable to take the medication on an empty stomach.
• Caffeine intake should be monitored as it can exacerbate nervousness and insomnia, which are potential side effects of the medication.
• Spicy foods may increase the risk of gastrointestinal issues, such as stomach upset and acid reflux, especially in individuals sensitive to spicy cuisine.
• Avoid excessive salt intake, as high-sodium diets can negatively impact blood pressure, and Rivastigmine may affect blood pressure in some individuals.
• Always ensure proper hydration when taking Rivastigmine, as adequate fluid intake supports overall health and may reduce certain side effects.
• Consult your healthcare provider for personalized advice on dietary considerations while using Rivastigmine.

Rivastigmine 5mg capsules should be stored in a cool and dry place, preferably at room temperature (below 25°C/77°F), ensuring protection from light and moisture. It is crucial to keep the medication in its original container, tightly sealed, to maintain its integrity and prevent contamination. Avoid exposing the capsules to extreme temperatures or storing them in bathrooms or kitchens, as heat and humidity can degrade the medication. Always check the expiration date, and do not use the capsules beyond this date. For proper disposal, do not flush the medication down the toilet or pour it into drainage systems; instead, follow local guidelines or consult a pharmacist for safe disposal methods. Keep the capsules out of children's reach to prevent accidental consumption.

Following are the quick tips for Rivastigmine 5mg Capsule:

• Ensure you take the capsule as directed by your doctor for effective treatment.
• Maintain a consistent daily dose timing to optimize treatment.
• Swallow the capsule whole with a glass of water, avoiding hot beverages.
• Do not break, crush, or chew the capsule for best results.
• If you have difficulty swallowing, consult your doctor for alternative options.
• Store the capsules in a cool, dry place, away from direct sunlight.
• Regularly monitor your health and inform your doctor of any changes.