Exforge (5/160mg) 28 Tablets

Amlodipine is a calcium channel blocker that relaxes the arteries and improves blood flow by preventing the movement of calcium ions into vascular smooth muscle cells. Valsartan, on the other hand, is an angiotensin II receptor type 1 (AT1) antagonist that reduces blood pressure by inhibiting vasoconstriction and aldosterone secretion. When combined in a single tablet, amlodipine and valsartan provide a dual mechanism of action that synergistically reduces blood pressure more effectively than each drug alone. This combination is known to be particularly effective in treating hypertension.

ARB, Calcium Channel Blocker

Unveiling its multifaceted uses and transformative applications as follows:

• Lowering of blood pressure
• Treatment of hypertensive emergencies and hypertension while pregnant
• Reduction of complications after transplant
• Treatment of heart failure
• Treatment of hypertension with atherosclerosis

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Amlodipine is a calcium channel blocker used to treat hypertension (elevated blood pressure).
• The recommended starting dose is 5-10 mg once daily.
• Valsartan is an angiotensin II receptor antagonist (sometimes called an ARB) and is used to treat high blood pressure.
• It is also used to decrease the risk of stroke in people who have had a stroke already.
• For adults, the typical starting dose is 80-160 mg by mouth once a day.

An Amlodipine 5mg and Valsartan 160mg overdose is not always treated the same way, as the treatment varies depending on the patient's unique medical history and how much they overdosed. In many cases, the treatment includes gastric lavage and general supportive measures, and it's important to note that if this is a medical emergency, immediate emergency assistance should be requested right away.

If you miss a dose of amlodipine 5mg and valsartan 160mg, there is no need to panic. The first step is to determine the timing of your missed dose. If it has been less than 12 hours since your scheduled dose, it is best to take the missed dose as soon as possible unless it is close to the time for your next dose. In that case, it is often recommended to skip the missed dose and maintain your regular dosing schedule to avoid exceeding the recommended dose. It is important to follow the instructions provided by your physician for the timing and dosage of your medication to ensure that you achieve the optimal therapeutic level and avoid any potential complications. However, if you are unsure about what to do, it is always best to contact your doctor or healthcare provider for guidance on how to handle the missed dose based on your specific situation. They may provide advice on whether you should take the missed dose, skip it, or make any changes to your regular dosing schedule. It is important to communicate any concerns or questions you may have regarding your missed dose or medication regimen so that you can make informed decisions about your health.

Amlodipine 5mg and Valsartan 160mg are medications that need to be taken once daily. When taking these pills, you must follow the instructions on the label and any directions provided by your doctor. It is important to read the medication box and ask your doctor or pharmacist for clarification if anything is unclear. Take these pills regularly at the same time each day as the timing is important for maintaining a consistent level of the medication in your bloodstream. These medications may be taken with or without food, but it is recommended to take them with food to prevent an upset stomach. Selecting a cool drink, preferably not alcoholic or grapefruit juice, is also recommended. Be sure to swallow these pills whole and not crush, break, or chew them as they are designed to be swallowed whole to release the active ingredients properly. If you miss a dose, take it as soon as you remember, but if it is closer to the time of your next dose, skip the missed dose and follow the regular schedule.

Discerning instances where this medication may not be appropriate:

• If you are allergic to either of the active ingredients (amlodipine or valsartan) or any of the inactive tablet ingredients.
• If you have certain heart problems such as aortic stenosis or muscular dystrophy.
• If you have liver problems or decreased liver function or an upcoming surgery or procedure in which you will receive anesthesia.
• If you are pregnant, plan to become pregnant, or are breastfeeding.
• If you have had a serious allergic reaction to similar medications in the past.
• It is important to provide your doctor with accurate and detailed information about your health history and update them on any

Unraveling the side effects lurking behind this medications are as follows:

• Dizziness
• Headache
• Tiredness
• Abdominal pain
• Constipation
• Nausea

Amlodipine Rare side effects

• Allergic reactions such as hives
• Swelling of the lips, face, throat, and tongue
• Itching
• Difficulty breathing

Valsartan Common side effects

• Dizziness
• Fatigue
• Weakness
• Nausea
• Coughing
• Difficulty breathing
• Swelling of the lips, tongue, and face

Valsartan serious side effects requiring immediate medical attention (rare cases)

• Sudden and rapid weight gain
• Severe headaches
• Unexplained abdominal or leg pain
• Valsartan may cause fetal harm when administered to a pregnant woman.

Here are the essential warnings and precautions for the use of the medication:

• Patients with sodium or volume depletion, idiopathic or hereditary angioedema, biliary obstructive disorders, or primary hyperaldosteronism should use this medication with caution. It should also be used carefully in patients with severe obstructive coronary artery disease, severe congestive heart failure (CHF), recent myocardial infarction (MI), mitral or aortic stenosis, hypertrophic cardiomyopathy with outflow tract obstruction, and diabetes mellitus (DM).
• Special attention is needed for patients undergoing surgery or dialysis.
• The medication should be used cautiously in those with renal conditions, such as chronic kidney disease or unilateral/bilateral renal artery stenosis, as well as in patients with mild to moderate hepatic impairment.
• The safety of the medication during lactation has not been well established, so it should only be used if advised by a healthcare provider.

Drug interactions with valsartan and amlodipine include:

• Other antihypertensives (e.g., diuretics, beta-blockers) (may have additive effects on blood pressure)
• Calcium channel blockers (e.g., diltiazem) (may have additive effects on blood pressure)
• ACE inhibitors (e.g., enalapril) (may have additive effects on blood pressure)
• NSAIDs (e.g., ibuprofen) (may reduce the antihypertensive effects of valsartan)
• Lithium (may increase lithium levels)

Amlodipine and valsartan are crucial medications for many individuals, and it is important to ensure their longevity and efficacy. These drugs are light sensitive and should be stored in a cool, dry place, away from sources of heat and moisture. It is best to keep them in an airtight container, preferably in the room temperature. It is recommended to avoid storage in the bathroom or any other humid areas inside the house. Also, these medications should be kept away from direct sunlight, hence windowsills are not suitable for storage. In addition, due to the potential harm to children, it is compulsory to store these medications safely out of children's reach. If you have any questions regarding the storage of these medications, be sure to consult your doctor or pharmacist for more specific instructions.