Ezimark (250mg) 10 Capsules

Azithromycin 250mg capsules exhibit their antibacterial activity through a unique mechanism of action. Primarily, azithromycin binds to the 50S ribosomal subunit of susceptible bacteria, thereby inhibiting protein synthesis. This binding interferes with the translation process, specifically targeting the peptide elongation phase. As a result, the bacteria's ability to produce essential proteins required for their survival and replication is disrupted. Azithromycin is particularly effective because it exhibits a long half-life, allowing for prolonged intracellular concentrations, which contributes to its efficacy against a wide range of bacterial infections.

Azithromycin 250mg

Macrolide antibiotic

Capsule

The following are the uses of Azithromycin 250mg Capsule:

• Used for treating bacterial infections such as pneumonia, bronchitis, and sinusitis.
• Used for respiratory tract infections, offering quick relief from symptoms.
• Used for skin infections like acne and rosacea, reducing inflammation.
• Used to combat ear infections, providing effective treatment.
• Used for certain stomach and intestinal infections, aiding digestion.
• Used for preventing and treating sexually transmitted infections.
• Used as a powerful tool against a range of bacterial illnesses.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Chlamydia 500 mg (1 tablet) on the first day, then 250 mg (half a tablet) daily for the next 4 days
• Gonorrhea 1000 mg (2 tablets) as a single dose
• Pharyngitis, tonsillitis, sinusitis, ear infections 500 mg (1 tablet) on the first day, then 250 mg (half a tablet) daily for the next 4 days
• Respiratory tract infections 500 mg (1 tablet) once a day for 3 days
• Skin infections 500 mg (1 tablet) once a day for 3 days

In the case of an overdose of Azithromycin 250mg Capsules, it is important to recognize the potential symptoms and take appropriate action. Common signs of an overdose may include nausea, vomiting, diarrhea, and abdominal pain. If you suspect an overdose, seek medical advice promptly. The healthcare provider may recommend steps such as inducing vomiting or administering activated charcoal to help minimize the absorption of the excess medication. Prompt medical intervention can help manage and mitigate the effects of an overdose.

In the case of a missed dose of Azithromycin 250mg Capsule, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance, as they may advise you to restart the medication or provide specific instructions to ensure you complete the full course of treatment.

To take Azithromycin 250mg Capsules, swallow the capsule whole with a full glass of water, preferably on an empty stomach, once daily for the duration prescribed by your healthcare provider, ensuring you complete the full course of medication as directed.

Following are the conditions/situations when Azithromycin 250mg Capsule should not be taken:

• Avoid if you have a known allergy to Azithromycin or any macrolide antibiotics.
• Do not take this medication if you have a history of prolonged QT interval or heart rhythm disorders.
• Contraindicated in patients with liver impairment or jaundice caused by previous macrolide use.
• Should not be used in individuals with myasthenia gravis.
• Not suitable for patients with a history of torsades de pointes.
• Avoid if you have ever had an allergic reaction to similar antibiotics, such as erythromycin.
• Do not take this medication if you are currently taking other medications that can affect your heart rhythm.

The side effects of Azithromycin 250mg Capsule may include:

• Nausea and vomiting
• Diarrhea
• Abdominal pain or discomfort
• Headache
• Dizziness
• Skin rashes or itching
• Fatigue and weakness
• Altered sense of taste

Following are the precautions and warnings for Azithromycin 250mg Capsule:

• This medication should not be taken by individuals with a known allergy to Azithromycin or related macrolide antibiotics.
• Patients with liver disease should use with caution, as Azithromycin is metabolized in the liver and dosage adjustments may be necessary.
• Caution is advised for patients with a history of irregular heart rhythms, as it may affect the electrical activity of the heart.
• Avoid prolonged or repeated use, especially in patients with myasthenia gravis, as it may worsen muscle weakness.
• Elderly patients may be more susceptible to side effects, particularly changes in heart rhythm and hearing.
• Azithromycin may interact with other medications; inform your doctor about all medications you are taking.
• If you experience severe diarrhea, persistent nausea, or signs of liver problems, stop taking the medication and seek medical attention immediately.

Following are the drug interactions for Azithromycin 250mg Capsule:

• Concomitant use with other antibiotics like Nelfinavir or Chlorpromazine can increase the risk of cardiac side effects, including QT prolongation.
• Azithromycin may reduce the effectiveness of live attenuated vaccines, such as measles or varicella vaccines, if given concurrently.
• Warfarin and other anticoagulants may have their effects enhanced, requiring close monitoring of coagulation parameters.
• Anticonvulsants like Carbamazepine can decrease Azithromycin levels, potentially reducing its effectiveness.
• The drug should be used cautiously with medications that affect liver function, as it is metabolized in the liver.
• Digoxin levels may be increased, requiring close monitoring of digoxin concentrations.
• Azithromycin may interact with antacids containing aluminum or magnesium, decreasing its absorption. Separate administration is recommended.
• The risk of hearing loss may be increased when taken with certain medications like Furosemide or Ethacrynic acid.

Following are the food interactions for Azithromycin 250mg Capsule:

• Avoid consuming grapefruit and grapefruit juice as they may interfere with the metabolism of Azithromycin, leading to increased drug levels in the body and potential side effects.
• Alcohol consumption should be limited or avoided as it can increase the risk of liver-related side effects and may reduce the effectiveness of the antibiotic.
• Dairy products like milk, yogurt, and cheese may decrease the absorption of Azithromycin. It is best to take the medication at least 2 hours before or after consuming dairy.
• Avoid high-fat meals as they can delay the absorption of Azithromycin, potentially reducing its effectiveness.
• Caffeine intake should be monitored as it may enhance the side effects of Azithromycin, especially nervousness and insomnia.
• Avoid eating large quantities of leafy greens like spinach and kale, as these are high in vitamin K, which can interact with Azithromycin and affect its anticoagulant properties.
• There is no specific interaction with herbs, but it's best to consult a doctor if you regularly consume herbal supplements to ensure no adverse effects.
• Always follow the dosage instructions provided by your healthcare professional to ensure the medication's effectiveness and minimize potential food-related interactions.

Azithromycin 250mg Capsules should be stored in a cool, dry place, preferably at room temperature between 68°F and 77°F (20°C and 25°C). Protect the capsules from direct exposure to sunlight and moisture by keeping them in their original packaging or a tightly sealed container. Avoid storing them in the bathroom medicine cabinet, as humidity can affect the medication. Always check the expiration date, and do not use the capsules if they have expired. For disposal, do not throw away Azithromycin capsules in regular household waste or flush them down the toilet. Consult your pharmacist or local waste disposal company for guidance on safe disposal methods to prevent harm to the environment. Keep the medication out of reach of children and pets to ensure their safety.

Following are the quick tips for Azithromycin 250mg Capsule:

• Take the capsule with a full glass of water to aid in swallowing and absorption.
• Ensure you complete the full prescribed course, even if you feel better before finishing all capsules.
• Take the capsule on an empty stomach, preferably 1 hour before or 2 hours after a meal.
• Avoid taking antacids or aluminum/magnesium-containing products within 2 hours of this medication.
• Store the capsules at room temperature, away from moisture and direct sunlight.
• Inform your doctor if you have liver disease or heart problems before taking this medication.
• Contact your doctor if you experience severe diarrhea, as it may indicate a new infection.

When Azithromycin is prescribed as an antibiotic, specific lab tests may be required to monitor your health and ensure the effectiveness of your treatment. These tests are guided by the purpose of your treatment and your medical history, which is why it's important to consult with a qualified professional who can assess your unique needs. To start, routine blood tests are commonly administered to monitor your overall health. This includes a complete blood count (CBC) to detect any abnormalities in your blood cells and platelets. Additionally, as Azithromycin can place a burden on the kidneys, it's important to monitor kidney function with tests like blood urea nitrogen (BUN) and creatinine. Liver function tests may also be required if higher doses of Azithromycin are prescribed, since the drug is metabolized by the liver. Since Azithromycin is a macrolide antibiotic, it poses a particular risk of hearing loss and inner ear damage. Hence, it is crucial to undergo a hearing test, specifically an audiometry test, to check for signs of auditory complications. Furthermore, Azithromycin can influence the levels of certain electrolytes in the body, so tests to monitor electrolyte levels, such as measuring sodium, potassium, calcium levels, and pH balance, may be recommended. These tests help rule out any imbalances or disruptions in your body's electrolyte balance. In summary, consulting with a knowledgeable medical professional is crucial to tailor the lab tests required while taking Azithromycin. They can best determine which tests are necessary and how frequently they should be administered to ensure both your safety and the success of your treatment.