Fasigyn (500mg) 40 Tablets

Tinidazole 500mg Tablet primarily works by interfering with the DNA synthesis of susceptible microorganisms, leading to their death or inhibition of growth. It selectively targets anaerobic bacteria and protozoa by disrupting their energy metabolism. The active component, tinidazole, is a nitroimidazole derivative that undergoes reduction within the cells of susceptible organisms, generating toxic metabolites. These metabolites bind to DNA, causing breakage and inhibition of DNA synthesis, which ultimately leads to the death of the microorganism. This mechanism of action makes tinidazole effective in treating various infections caused by anaerobic bacteria and certain protozoa.

Antiprotozoal and Antibacterial.

Tablet

The following are the uses of Tinidazole 500mg Tablet:

• Used for treating bacterial infections, particularly those in the abdomen, intestine, liver, and genital area.
• Used to eliminate certain bacteria from the gut before surgery or procedures.
• Used for treating vaginal infections caused by bacteria or parasites.
• Used to combat parasitic infections, such as giardiasis and amebiasis.
• Used for reducing the symptoms of these infections, including diarrhea, abdominal pain, and fever.
• Used as an alternative for patients who cannot tolerate other antibiotics.
• Used in combination with other medications for comprehensive treatment.

Follow these dosage instructions:

• Adult Dosage

2 grams once a day for 3-5 days. Your doctor may adjust your dose as needed.

• Child Dosage

The dosage for the child is strictly recommended by the doctor.

In the case of an overdose of Tinidazole 500mg Tablets, the patient may experience an increase in the severity of common side effects such as nausea, vomiting, headaches, and dizziness. Additionally, more serious symptoms like seizures, confusion, and difficulty breathing might occur. It is important to seek medical advice promptly, as the doctor may recommend symptomatic treatment and supportive measures to manage the overdose effectively. Timely intervention can help prevent potential complications.

In the case of a missed dose of Tinidazole 500mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one. Avoid taking a double dose to make up for the missed one. It is crucial to maintain a consistent medication schedule, but if you miss a dose, consult your healthcare provider for guidance on how to proceed. They can provide specific instructions based on your medical history and the reason for the prescription.

To take Tinidazole 500mg Tablet, swallow the tablet whole with a full glass of water, preferably during or after a meal, exactly as prescribed by your doctor, usually once or twice a day for the duration of the prescribed treatment period.

Following are the conditions when Tinidazole 500mg Tablet should not be taken:

• Should not be used if you are allergic to Tinidazole or other similar medications (such as Metronidazole).
• Contraindicated in patients with a history of blood disorders or severe liver disease.
• Not recommended for individuals with a history of seizures or epilepsy.
• Avoid using this medication if you have recently taken disulfiram or any other alcohol-containing products.
• Should not be used if you have a history of severe skin reactions to medications.
• Contraindicated during the first trimester of pregnancy and in breastfeeding mothers.
• Not suitable for individuals with a history of porphyria (a group of disorders affecting the skin and nervous system).

The side effects of Tinidazole 500mg Tablet may include:

• Nausea and vomiting
• Dry mouth
• Metallic taste in the mouth
• Loss of appetite
• Darkened urine
• Headache
• Dizziness or lightheadedness
• Abdominal pain or discomfort

Following are the precautions and warnings for Tinidazole 500mg Tablet:

• Avoid alcohol consumption while taking this medication and for at least 3 days after completing the treatment, as it may cause severe nausea, vomiting, and other unpleasant side effects.
• Not recommended for individuals with a history of blood disorders or severe liver disease, as it can worsen these conditions.
• Elderly patients may be more susceptible to the side effects of this medication, and close monitoring is necessary.
• Patients with kidney problems should use this medication with caution, and dosage adjustments might be required.
• Inform your doctor if you have any other medical conditions, especially if you have epilepsy or other seizure disorders.
• This medication may cause dizziness or drowsiness, so avoid driving or operating heavy machinery until you know how it affects you.
• Tinidazole may interact with other medications; inform your healthcare provider about all the medicines you are currently taking.
• Consult your doctor immediately if you experience any severe or unusual side effects during or after the treatment period.

Following are the drug interactions for Tinidazole 500mg Tablet:

• Alcohol consumption should be avoided during and for at least 3 days after treatment with Tinidazole, as it can cause a disulfiram-like reaction with symptoms like flushing, nausea, and palpitations.
• Tinidazole may reduce the effectiveness of hormonal contraceptives, including birth control pills, patches, or rings, and emergency contraception. Alternative birth control methods are recommended during and for several days after treatment.
• Tinidazole may decrease the plasma concentration of brivudine, potentially reducing its antiviral effect. Monitoring for brivudine-related side effects is advised.
• It can interact with anticoagulants like warfarin, possibly enhancing the anticoagulant effect and increasing the risk of bleeding. Regular monitoring of coagulation parameters is recommended.
• Tinidazole may increase the risk of peripheral neuropathy when used with other neurotoxic drugs, such as certain antiretrovirals or chemotherapy medications.
• Caution is advised when combining Tinidazole with other central nervous system (CNS) depressants, as it may enhance their effects and cause increased sedation or drowsiness.
• Prolonged use of Tinidazole may reduce the efficacy of live bacterial vaccines (e.g., typhoid vaccine) due to its antimicrobial properties.

Following are the food interactions to be aware of when taking Tinidazole 500mg Tablet:

• Alcohol consumption should be avoided during and a few days after the treatment with Tinidazole as it can cause unpleasant side effects like flushing, headache, increased heart rate, nausea, and vomiting.
• Avoid grapefruit and grapefruit juice as they can interfere with the metabolism of Tinidazole, potentially increasing its levels in the blood and the risk of side effects.
• Dairy products like milk, cheese, and yogurt may reduce the absorption of Tinidazole, so it's best to separate these by a few hours.
• Fatty foods can slow down the absorption of Tinidazole, so it's advisable to avoid high-fat meals while taking this medication.
• Caffeine intake should be limited as it can increase the likelihood of Tinidazole-related side effects, particularly nervousness and insomnia.
• Avoid eating spoiled or fermented foods, as they may contain bacteria that can interact with Tinidazole, reducing its effectiveness.
• Consuming a healthy diet rich in fruits, vegetables, and whole grains can support your body during the treatment, aiding in recovery and maintaining overall health.
• Always follow the advice of your healthcare provider regarding specific dietary restrictions or recommendations while taking Tinidazole.

Tinidazole 500mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from direct sunlight and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial not to store the tablets in the bathroom or near heat-emitting appliances, as temperature fluctuations can impact their effectiveness. Dispose of any unused or expired tablets responsibly by avoiding flushing or pouring them down the drain; consult your pharmacist for guidance on proper disposal methods. Always keep medications out of children's reach to prevent accidental consumption.

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Following are the quick tips for Tinidazole 500mg Tablet:

• Consult a doctor for prescription and dosage instructions.
• Take the tablet with or without food as directed by your healthcare provider.
• Ensure you complete the full course of treatment, even if you feel better earlier.
• Avoid alcohol consumption during treatment and for at least 3 days after, as it may cause side effects.
• Inform your doctor about any other medications or supplements you're taking.
• Store the tablets at room temperature, away from moisture and sunlight.
• Do not share the medication with others, even if their symptoms are similar.