Fastum (2.5%) 50g Gel

Ketoprofen gel works by inhibiting the production of certain chemicals in the body known as prostaglandins. It achieves this through its active ingredient, ketoprofen, which is a nonsteroidal anti-inflammatory drug (NSAID). When applied topically, ketoprofen penetrates the skin and targets specific enzymes called cyclooxygenase (COX) enzymes. These enzymes play a crucial role in the synthesis of prostaglandins, which are involved in pain and inflammation processes. By blocking the action of COX enzymes, ketoprofen gel reduces the production of prostaglandins, thereby alleviating pain and decreasing inflammation in the affected area. This localized mechanism of action allows for targeted relief without affecting the entire body, making it a valuable option for treating various musculoskeletal conditions.

Ketoprofen

Non-steroidal anti-inflammatory drug (NSAID)

Gel

The following are the uses of Ketoprofen Gel:

• Used for relieving pain and reducing inflammation in muscles, joints, and tendons.
• Used for treating conditions like sprains, strains, back pain, and arthritis.
• Used for providing localized pain relief and reducing swelling in affected areas.
• Used for managing post-surgical pain and inflammation.
• Used for aiding in sports injuries recovery by reducing pain and stiffness.
• Used for treating tendonitis and bursitis.
• Used for easing pain and improving mobility in individuals with chronic pain conditions.
• Used for offering a non-invasive pain management option with fewer systemic side effects.

To be taken as per doctor's prescription

In the case of an overdose of Ketoprofen Gel, the severity of symptoms can vary depending on the amount used. Common signs may include stomach pain, nausea, and vomiting. More serious cases could lead to gastrointestinal bleeding, dizziness, or even a decrease in urine output. It is important to note that if any adverse effects occur, seeking medical advice promptly is recommended. Timely consultation can help manage potential complications effectively.

In the case of a missed dose of Ketoprofen Gel, it is important to apply the gel as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra gel to make up for a missed dose, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare professional for guidance on how to safely resume your treatment and ensure the best possible outcomes.

To apply Ketoprofen Gel, clean and dry the affected area, then squeeze a small amount of gel onto your fingertips and gently rub it into the skin using a circular motion until it is fully absorbed, usually 2 to 4 times a day or as directed by your healthcare professional.

Following are the conditions when Ketoprofen Gel should not be used:

• Avoid using in individuals with a known allergy or hypersensitivity to Ketoprofen, aspirin, or other NSAIDs (Non-Steroidal Anti-Inflammatory Drugs).
• Do not use on broken or infected skin.
• Contraindicated in individuals with a history of asthma or severe allergic reactions triggered by aspirin or other NSAIDs.
• Not recommended for use on skin conditions caused by chickenpox or shingles.
• Avoid using on areas where the skin is severely damaged or has open wounds.
• Do not use around the eyes, nose, mouth, or on genital areas.
• Should not be used on children below the age of 16 years without medical advice.
• Contraindicated in individuals with a history of gastrointestinal bleeding or perforation.

The side effects of Ketoprofen Gel may include:

• Skin irritation at the application site, such as redness, itching, or rash.
• Dry skin or peeling.
• Mild burning or stinging sensation.
• Swelling or inflammation of the skin.
• Allergic reactions, including hives and difficulty breathing.
• Increased sensitivity to sunlight (photosensitivity).
• Headache or dizziness.
• Gastrointestinal discomfort, including nausea and stomach pain.

Following are the precautions and warnings:

• Ketoprofen Gel should not be used on open wounds, infected areas, or skin conditions like eczema or dermatitis.
• Avoid contact with eyes, nose, mouth, and other mucous membranes. Wash your hands thoroughly after application.
• Do not cover the treated area with airtight dressings or bandages as it may increase the risk of skin reactions.
• Wash your hands thoroughly after applying the gel to avoid accidental transfer to sensitive areas.
• Do not use this medication for more than 10 days without consulting a healthcare professional.
• Avoid using Ketoprofen Gel on large areas of the body or over extended periods, especially in children and the elderly, as it may increase the risk of side effects.
• Inform your doctor if you have a history of asthma, allergic reactions to aspirin or other NSAIDs, or any other medical conditions before using this medication.

Following are the drug interactions for Ketoprofen Gel:

• Ketoprofen Gel may interact with other topical medications containing NSAIDs, potentially increasing the risk of skin irritation and other adverse effects.
• Avoid using aspirin or other oral NSAIDs while using the gel, as it may lead to increased side effects such as gastrointestinal bleeding.
• Concomitant use with corticosteroids can increase the risk of gastrointestinal bleeding and delay wound healing.
• It may interact with anticoagulants like warfarin, potentially affecting blood clotting and increasing the risk of bleeding.
• The gel's absorption can be increased by drugs that open tight junctions of the skin, potentially leading to higher ketoprofen levels in the body.
• Combining with other drugs that increase photosensitivity, such as certain antibiotics, may enhance the risk of sunburn and skin reactions.
• Ketoprofen Gel may interact with lithium, increasing lithium blood levels and the risk of lithium toxicity.

Following are the food interactions to be aware of when using Ketoprofen Gel:

• Ketoprofen Gel should not be applied on or near the eyes, mouth, or open wounds. Avoid contact with these areas to prevent irritation.
• Avoid eating grapefruit or drinking grapefruit juice while using Ketoprofen Gel, as grapefruit can affect the metabolism of the drug, potentially increasing its levels in the body.
• Limit alcohol consumption as it may increase the risk of gastrointestinal bleeding when combined with Ketoprofen Gel. Alcohol can also enhance the risk of liver damage.
• Inform your healthcare provider if you consume large amounts of coffee or tea (caffeine), as this may require adjustments in your treatment.
• Avoid high-fat meals as they may affect the absorption of the medication. It is best to apply the gel on clean, dry skin after meals.
• If you are on a low-salt diet, consult your doctor before using Ketoprofen Gel, as some formulations may contain sodium.
• Avoid foods rich in vitamin K (like leafy greens) if you are at risk of blood clots, as Ketoprofen may interfere with blood clotting.
• Always follow the advice of your healthcare provider regarding dietary restrictions or specific food interactions.

Ketoprofen Gel should be stored at room temperature, away from excessive heat and direct sunlight. Keep the tube tightly sealed when not in use to maintain its integrity. Avoid storing it in the bathroom or refrigerator as temperature and humidity fluctuations can impact its effectiveness. Always check the expiration date, and do not use the gel if it has expired. Dispose of any unused or expired gel by following local guidelines for pharmaceutical waste disposal, ensuring it is not poured down the drain or flushed into the sewage system. Keep the medication out of children's reach to prevent accidental exposure. Proper storage and disposal are essential to maintain the safety and efficacy of Ketoprofen Gel.

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Following are the quick tips for Ketoprofen Gel:

• Wash your hands before and after applying the gel to ensure hygiene.
• Clean and dry the affected area before applying the gel.
• Apply a thin layer of gel to the skin and gently rub it in until absorbed.
• Avoid applying the gel on broken or irritated skin.
• Do not cover the treated area with bandages or tight clothing to allow the gel to breathe.
• Wash your hands thoroughly after application, especially before touching your eyes or face.
• Store the gel at room temperature, away from direct sunlight or extreme heat.