Ferbex Syrup 240ml

Phenylephrine, a sympathomimetic amine, primarily acts by selectively stimulating alpha-adrenergic receptors, particularly alpha-1 receptors in the arterioles of the nasal mucosa. This stimulation causes vasoconstriction, leading to reduced blood flow and congestion relief. Paracetamol, an analgesic and antipyretic, exerts its effects through multiple mechanisms. It inhibits the synthesis of prostaglandins, which are involved in pain and inflammation, by blocking the enzyme cyclooxygenase (COX). Paracetamol also acts on the brain's heat-regulating center to reduce fever. When administered orally, both drugs are well-absorbed, allowing phenylephrine to constrict blood vessels and decrease nasal congestion, while paracetamol effectively reduces pain and fever.

Antihistamine, Analgesic

Suspension

The following are the uses of Phenylephrine, Paracetamol Syrup/Suspension:

• Used for relieving nasal congestion and reducing stuffy noses
• Used for lowering fever and reducing pain associated with headaches and body aches
• Used for treating symptoms of common colds and flu
• Used for easing discomfort from sinus pressure and congestion
• Used for managing mild to moderate pain, including toothaches and post-vaccination pain
• Used for providing temporary relief from minor aches and pains
• Used for helping with sore throat pain and inflammation

In the case of an overdose of Phenylephrine and Paracetamol Syrup/Suspension, individuals may experience severe symptoms. These can include rapid heartbeat, elevated blood pressure, and in extreme cases, cardiovascular complications. Additionally, an overdose of Paracetamol may lead to liver damage, requiring urgent medical intervention. Prompt medical assessment and treatment are necessary to manage the adverse effects and ensure the patient's well-being.

In the case of a missed dose of Phenylephrine, Paracetamol Syrup/Suspension, administer the dose as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to make up for the missed one. If you miss multiple doses, consult your healthcare professional for guidance on how to safely resume the medication. It is important to maintain a consistent dosing routine for the best therapeutic effect.

To administer Phenylephrine and Paracetamol Syrup/Suspension, shake the bottle well, measure the prescribed dose with a measuring cup or oral syringe, and give it to the patient orally, following the dosage instructions provided by the healthcare professional, typically taken every 4 to 6 hours as needed, without exceeding the maximum daily dosage.

Following are the conditions/situations when Phenylephrine and Paracetamol Syrup/Suspension should not be used:

• Avoid using this medication if you have an allergy to Phenylephrine, Paracetamol, or any other similar decongestants or analgesics.
• Do not administer to infants or young children without medical advice.
• Not recommended for individuals with severe high blood pressure or cardiovascular disease.
• Contraindicated in patients with narrow-angle glaucoma.
• Should not be used if you have taken a monoamine oxidase inhibitor (MAOI) in the last 14 days.
• Avoid using if you have difficulty in urination due to an enlarged prostate.
• Not suitable for individuals with diabetes, as Paracetamol may affect blood sugar levels.
• Do not use if you have liver or kidney disease without medical advice.
• Should not be combined with other cold, allergy, or pain medications without consulting a healthcare professional.
• Contraindicated in patients with pheochromocytoma.

The side effects of Phenylephrine, Paracetamol Syrup/Suspension may include:

• Nausea and vomiting
• Dizziness or lightheadedness
• Headache
• Nervousness or anxiety
• Insomnia (difficulty sleeping)
• Palpitations (rapid or pounding heartbeat)
• Increased blood pressure
• Skin rashes or itching

Following are the precautions and warnings for Phenylephrine, Paracetamol Syrup/Suspension:

• This medication should not be used in patients with a known allergy or sensitivity to Phenylephrine or Paracetamol.
• It should be used with caution in patients with high blood pressure, heart disease, diabetes, or thyroid problems as it may exacerbate these conditions.
• Do not exceed the recommended dosage, as it may lead to serious liver damage.
• Avoid using this medication if you are taking monoamine oxidase inhibitors (MAOIs) or have taken them within the last 14 days.
• Patients with kidney or liver disease should use this medication with caution and under medical supervision.
• Elderly patients may be more sensitive to the effects and side effects of this medication.
• Consult a healthcare professional if symptoms persist or worsen after using this syrup/suspension.
• Keep out of reach of children.

Following are the drug interactions for Phenylephrine, Paracetamol Syrup/Suspension:

• May interact with monoamine oxidase inhibitors (MAOIs), increasing the risk of hypertension and cardiovascular events.
• Concomitant use with other sympathomimetic agents may cause elevated blood pressure and heart rate.
• Can increase the effects of antihypertensive medications, leading to hypotension.
• Phenylephrine may reduce the effectiveness of beta-blockers and alpha-blockers.
• Paracetamol can potentially interact with anticoagulants, increasing the risk of bleeding.
• Concomitant use with other analgesics or antipyretics may lead to increased risk of liver toxicity.
• Avoid use with alcohol as it may enhance the sedative effects of paracetamol.

Following are the food interactions for Phenylephrine, Paracetamol Syrup/Suspension:

• Alcohol consumption should be avoided as it may increase the risk of liver damage, especially when Paracetamol is taken in high doses or for extended periods.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of Phenylephrine, potentially leading to increased blood pressure and heart rate.
• Caffeine-containing beverages like coffee, tea, and energy drinks may increase the stimulatory effects of Phenylephrine, causing restlessness and increased heart rate.
• Avoid high-fat meals as they may slow down the absorption of Paracetamol, delaying its pain-relieving effects.
• Consuming foods rich in Vitamin C, like citrus fruits, may enhance the absorption of Phenylephrine, potentially increasing its effectiveness.
• Avoid excessive salt intake as it may counteract the effects of Phenylephrine in reducing nasal congestion.
• Spicy foods may exacerbate symptoms like runny nose and sneezing, especially when taken in conjunction with Phenylephrine.
• There are no significant food restrictions with this medication, but it's advisable to maintain a balanced diet and stay well-hydrated.

Phenylephrine and Paracetamol Syrup/Suspension should be stored in a controlled environment, preferably in a cool and dry place, away from direct sunlight and moisture. Maintain the medication at room temperature, ensuring the container is tightly sealed to prevent contamination. Avoid exposing the medication to extreme temperatures by keeping it away from heat sources or cold environments. Regularly check the expiration date, and dispose of any unused or expired syrup responsibly. Do not dispose of it through household waste or water systems; instead, follow local guidelines or consult healthcare professionals for appropriate disposal methods. Keep the medication securely stored, out of children's reach, to prevent accidental consumption.

Following are the quick tips for Phenylephrine, Paracetamol Syrup/Suspension:

• Always read the medication label and follow the dosage instructions provided by your healthcare professional.
• Shake the bottle thoroughly before each use to ensure proper mixing.
• Administer the syrup with a measuring cup or oral syringe for accurate dosing.
• Store the medication at room temperature, away from direct sunlight and moisture.
• Do not use if the syrup changes color or develops an unusual odor.
• Consult your doctor or pharmacist if symptoms persist or worsen despite using the medication.
• Inform your healthcare provider about any other medications you are taking to avoid potential interactions.