Fern-D (1000IU) 120 Softgels Capsule

Cholecalciferol, also known as vitamin D3, has a specific mechanism of action. When ingested, cholecalciferol undergoes two hydroxylation reactions in the body to become its active form, calcitriol. The first hydroxylation occurs in the liver, converting cholecalciferol to 25-hydroxyvitamin D (calcidiol). Subsequently, the kidneys perform the second hydroxylation, transforming calcidiol into 1,25-dihydroxyvitamin D (calcitriol). Calcitriol acts as a hormone, binding to vitamin D receptors (VDRs) in various tissues, primarily targeting the intestine, kidneys, and bones. This binding activates the VDR, which then forms a complex that regulates gene expression. In the intestine, it enhances calcium and phosphate absorption, promoting bone mineralization. In the kidneys, it influences calcium reabsorption, and in bones, it stimulates osteoclasts, contributing to bone remodeling and calcium homeostasis.

Cholecalciferol 1,000iu

Vitamin D3 supplement

Capsule

The following are the uses of Cholecalciferol 1,000iu Capsule:

• Used for treating and preventing Vitamin D deficiency, ensuring your body gets enough of this essential nutrient.
• Used for bone health, helping to strengthen and maintain strong bones by improving calcium absorption.
• Used for supporting immune function, as Vitamin D plays a role in regulating and boosting the immune system.
• Used for improving muscle strength and reducing the risk of falls, especially in older adults.
• Used for managing conditions like rickets and osteomalacia, where Vitamin D deficiency is a key factor.
• Used for enhancing overall well-being, as Vitamin D is crucial for various bodily functions.
• Used for promoting healthy skin, as it plays a role in skin cell growth and repair.
• Used for supporting cardiovascular health, as Vitamin D may help regulate blood pressure and reduce inflammation.

In the case of an overdose of Cholecalciferol 1,000iu Capsules, individuals may experience symptoms such as nausea, vomiting, constipation, and elevated calcium levels in the blood. Promptly seek medical advice if you suspect an overdose, as treatment may involve supportive care and managing any complications. The severity of symptoms can vary, and medical professionals will determine the appropriate course of action based on the individual's health status and the extent of the overdose.

In the case of a missed dose of Cholecalciferol 1,000iu Capsule, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Avoid taking extra doses to make up for a missed one, as this may lead to potential side effects. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track with your medication regimen.

To take Cholecalciferol 1,000iu Capsules, swallow the capsule whole with a glass of water, preferably with a meal or as directed by your healthcare professional, once a day at the same time each day.

Here are the conditions or situations when Cholecalciferol 1,000 IU Capsule should not be taken:

• Should not be used in individuals with a known hypersensitivity or allergy to vitamin D or any of the excipients in the capsule.
• Contraindicated in individuals with hypercalcemia (high levels of calcium in the blood) or conditions that lead to elevated calcium levels, such as primary hyperparathyroidism.
• Not recommended for patients with conditions causing hypervitaminosis D (excess vitamin D) or those who are taking other vitamin D supplements or medications containing vitamin D.
• Should be avoided in patients with kidney stones or conditions that increase the risk of developing kidney stones, such as hypercalciuria (high levels of calcium in urine).
• Contraindicated in individuals with Williams syndrome, a genetic disorder affecting multiple systems in the body.
• Not suitable for patients with sarcoidosis, a condition characterized by the formation of inflammatory nodules in various organs, as it can lead to excessive calcium absorption.
• Should not be used in patients with idiopathic hypercalciuria, a condition where high levels of calcium are excreted in the urine without an identifiable cause.

The side effects of Cholecalciferol 1,000iu Capsule may include:

• Nausea and vomiting
• Weakness and fatigue
• Dry mouth
• Metallic taste
• Constipation or diarrhea
• Loss of appetite
• Muscle or joint pain

Following are the precautions and warnings for Cholecalciferol 1,000iu Capsule:

• Avoid high doses of Cholecalciferol if you have a history of kidney stones, as it can increase the risk of stone formation.
• Individuals with hypercalcemia (high calcium levels in the blood) should not take this supplement without medical supervision.
• Patients with conditions affecting calcium metabolism, such as hyperparathyroidism, should exercise caution and consult a healthcare professional.
• Regular monitoring of calcium levels is recommended for long-term users to prevent potential toxicity.
• Inform your doctor if you have any liver or kidney diseases before starting this medication.
• Do not take more than the recommended dosage, as excessive vitamin D intake can lead to serious side effects.
• Cholecalciferol may interact with certain medications; consult your healthcare provider about potential interactions.
• Keep out of reach of children, as accidental overdose can be harmful.

Following are the drug interactions for Cholecalciferol 1,000iu Capsule:

• Anticonvulsant medications such as phenobarbital, phenytoin, and carbamazepine can reduce the effectiveness of cholecalciferol by increasing its metabolism.
• Cholestyramine, a bile acid sequestrant, can bind to cholecalciferol in the intestine, reducing its absorption and effectiveness.
• Orlistat, a weight-loss medication, can decrease the absorption of fat-soluble vitamins like cholecalciferol, potentially leading to vitamin D deficiency.
• Thiazide diuretics (e.g., hydrochlorothiazide) can increase the risk of hypercalcemia when used with cholecalciferol, especially in patients with renal impairment.
• Aluminum-containing antacids may decrease the absorption of cholecalciferol by forming insoluble complexes in the intestine.
• Mineral oil laxatives can interfere with the absorption of fat-soluble vitamins, including cholecalciferol, when taken simultaneously.
• Corticosteroids like prednisone may increase the catabolism of vitamin D, potentially reducing the effectiveness of cholecalciferol supplementation.

Following are the food interactions for Cholecalciferol 1,000 IU Capsule:

• Consuming foods rich in Vitamin D, such as fatty fish (salmon, tuna), egg yolks, and fortified dairy products, alongside the supplement may lead to excessive Vitamin D intake, potentially causing hypervitaminosis D.
• Vitamin D is fat-soluble, so it's best taken with a meal containing healthy fats to enhance absorption, ensuring maximum benefit.
• Avoid excessive consumption of calcium-rich foods like dairy products and leafy greens, as Vitamin D increases calcium absorption, and high calcium levels can lead to hypercalcemia.
• Limit caffeine intake, as caffeine may interfere with Vitamin D absorption and utilization.
• Alcohol should be consumed in moderation, as excessive alcohol can interfere with Vitamin D metabolism and reduce its effectiveness.
• Grapefruit and grapefruit juice may affect the metabolism of Vitamin D and should be consumed with caution.
• A balanced diet with a variety of foods ensures a steady supply of nutrients, which can complement the Vitamin D supplementation and support overall health.
• Always consult a healthcare provider for personalized advice on diet and supplement interactions.

Cholecalciferol 1,000iu Capsules should be stored in a cool and dry place, preferably in a medicine cabinet or a designated storage area, away from direct sunlight and moisture. It is crucial to keep the capsules in their original packaging, ensuring the container is tightly sealed to maintain their integrity. Avoid exposing the medication to extreme temperatures, including hot environments like near ovens or cold places like refrigerators, as this can impact its effectiveness. Always check the expiration date before using the capsules, and if expired, dispose of them safely. Proper disposal methods include returning the medication to a pharmacy or following local guidelines for pharmaceutical waste disposal. Keep the capsules out of children's reach to prevent accidental consumption.

Following are the quick tips for Cholecalciferol 1,000iu Capsule:

• Take the capsule as directed by your doctor or healthcare professional.
• Swallow the capsule whole with a full glass of water, preferably with a meal or as advised.
• Maintain a consistent daily routine for taking the capsule for best results.
• Cholecalciferol can be taken at any time, but taking it with a meal can aid absorption.
• Do not crush, chew, or break the capsule; swallow it whole.
• Inform your doctor if you have any medical conditions or are taking other medications.
• Store the capsules in a cool, dry place, away from direct sunlight and moisture.