FERROTON SYP

Ferrous fumarate is an oral iron supplement used to treat iron deficiency anemia. Its mechanism of action involves replenishing the body's iron stores, which are essential for the production of red blood cells and proper oxygen transport. When ingested, ferrous fumarate dissociates in the stomach, releasing iron ions that bind to transferrin, a transport protein. This iron-transferrin complex is then absorbed in the small intestine, primarily in the duodenum and upper jejunum. The absorbed iron is utilized by the body for various physiological processes, including hemoglobin synthesis, myoglobin production, and enzymatic reactions, ultimately helping to restore iron balance and alleviate anemia.

Oral iron

Suspension

The following are the uses of ferrous fumarate Syrup/Suspension:

• Used for treating iron deficiency anemia, ensuring red blood cells can effectively carry oxygen.
• Used for replenishing iron stores in the body, especially during pregnancy or heavy menstrual periods.
• Used for enhancing iron absorption, particularly when paired with Vitamin C.
• Used for managing anemia symptoms like fatigue and weakness.
• Used for maintaining overall health and energy levels.
• Used for supporting proper growth and development in children and adolescents.
• Used for preventing anemia in high-risk individuals.

In the case of an overdose of Ferrous Fumarate Syrup/Suspension, the primary concern is the potential for iron toxicity. Symptoms may include gastrointestinal issues such as nausea, vomiting, and abdominal pain. In severe cases, it can lead to circulatory and respiratory problems. Prompt medical intervention is necessary, involving gastric lavage and supportive care to manage symptoms and prevent further complications. Timely treatment can help mitigate the risks associated with iron overdose.

In the case of a missed dose of ferrous fumarate Syrup/Suspension, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication.

To take ferrous fumarate syrup/suspension, shake the bottle well, then measure the prescribed dose using a dosing cup or oral syringe, and administer it orally, following the dosage instructions provided by your healthcare professional, typically taken once or twice a day, with or without food, as directed.

Following are the conditions or circumstances when ferrous fumarate Syrup/Suspension should not be administered:

• Must not be given to individuals with a known allergy or hypersensitivity to ferrous fumarate or any of the excipients in the formulation.
• Contraindicated in patients with hemochromatosis, hemosiderosis, or other conditions associated with iron overload.
• Not recommended for individuals with hemolytic anemia.
• Avoid use in patients with an acute infection or inflammation, as iron absorption may be impaired.
• Should not be administered to patients with untreated or uninvestigated abdominal pain.
• Not suitable for those with a history of gastrointestinal disorders that may interfere with iron absorption, such as inflammatory bowel disease.
• Avoid use in patients with a history of alcohol abuse or liver disease, as this may affect iron metabolism.
• Must not be given to patients with a history of repeated blood transfusions without monitoring iron levels.

The side effects of Ferrous Fumarate Syrup/Suspension may include:

• Nausea and vomiting
• Stomach cramps or pain
• Diarrhea or constipation
• Darkened stools
• Temporary staining of teeth (especially in children)
• Metallic taste in the mouth
• Abdominal discomfort
• Skin rash or itching

Following are the precautions and warnings for ferrous fumarate Syrup/Suspension:

• Do not exceed the recommended dosage, as iron overload can occur with excessive use.
• Keep out of reach of children. Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6 years old.
• This medication should be used with caution in patients with gastrointestinal disorders, as it may cause stomach upset, nausea, or constipation.
• Patients with a history of kidney disease or those undergoing regular blood transfusions should use it under medical supervision.
• Ferrous fumarate can cause temporary staining of teeth. Rinsing the mouth with water after taking the medication can help minimize this effect.
• Alcohol may interfere with the absorption of iron; it is advisable to avoid consuming alcohol while taking this medication.
• If symptoms of iron deficiency anemia do not improve or worsen, consult a healthcare professional immediately.
• Always inform your doctor about all the medications you are taking to avoid potential drug interactions.

Following are the drug interactions for ferrous fumarate Syrup/Suspension:

• Antacids containing aluminum or magnesium can decrease the absorption of ferrous fumarate, so separate administration by at least 2 hours.
• Concomitant use with tetracycline antibiotics can reduce the absorption of both drugs, so separate doses by 2-3 hours.
• Ferrous fumarate may decrease the effectiveness of levothyroxine, so it's best to separate doses by at least 4 hours.
• The absorption of ferrous fumarate can be impaired by caffeine, so avoid taking them together.
• Co-administration with chloramphenicol may lead to decreased absorption of both drugs.
• Iron may reduce the efficacy of levodopa in Parkinson's disease.
• Protons pump inhibitors like omeprazole can reduce iron absorption, so separate administration by 2 hours.

Following are the food interactions for Ferrous Fumarate Syrup/Suspension:

• Avoid consuming dairy products like milk, cheese, or calcium supplements simultaneously with Ferrous Fumarate, as calcium can decrease iron absorption. Separate intake by at least 2 hours.
• Foods rich in vitamin C, such as citrus fruits, strawberries, and bell peppers, can enhance iron absorption. Consider pairing these foods with your Ferrous Fumarate dose.
• Coffee, tea, and foods high in polyphenols can hinder iron absorption. Avoid consuming these items with your medication.
• Whole grain products and high-fiber foods may reduce iron absorption. Try to maintain a balanced diet, but consider taking Ferrous Fumarate between meals for better absorption.
• Avoid alcohol consumption while taking Ferrous Fumarate, as it can irritate the stomach and potentially worsen gastrointestinal side effects.
• Certain foods like spinach, rhubarb, and chocolate contain oxalic acid, which can bind with iron and reduce its absorption. Limit these foods around the time of medication intake.
• Eggs, especially the yolks, contain a compound called phosvitin, which can also inhibit iron absorption. Consider separating egg consumption from your medication schedule.

Ferrous fumarate Syrup/Suspension should be stored in a cool and dry environment, preferably at room temperature, ensuring protection from light and moisture. Keep the medication securely sealed in its original container to maintain its integrity. Avoid storage in bathrooms or near heat-emitting appliances to prevent degradation. Adhere to proper disposal practices by refraining from flushing or pouring down drains; consult your pharmacist for guidance on environmentally friendly disposal methods. Exercise caution to store the medication out of children's reach to prevent accidental consumption. Regularly inspect the expiration date, discarding any outdated or unused portions responsibly.

Following are the quick tips for Ferrous Fumarate Syrup/Suspension:

• Always consult your doctor before starting this medication, especially if you have existing medical conditions.
• Measure the dose accurately using the measuring cup provided or a marked syringe.
• Administer the syrup slowly and follow it with a glass of water or juice to enhance taste.
• Store the medication at room temperature, away from direct sunlight and moisture.
• Do not share this medication with others, even if they have similar symptoms.
• If you experience constipation, increase your fluid intake and dietary fiber.
• Regularly monitor your blood iron levels while taking this medication.