Fevonor injection

Paracetamol primarily acts by inhibiting the synthesis of prostaglandins in the central nervous system, which reduces pain sensitivity. It may also exert its effects through additional mechanisms, including direct action on the brain's heat-regulating center, which helps to reduce fever. On the other hand, Lidocaine injection is a local anesthetic that blocks voltage-gated sodium channels in nerve membranes, preventing the initiation and conduction of nerve impulses, thereby providing temporary pain relief and local anesthesia.

Analgesic/Antipyretic and Local Anesthetic

injection

The following are the uses of Paracetamol, Lidocaine injection:

• Used for relieving pain and reducing fever
• Used for local anesthesia, numbing specific areas for pain-free procedures
• Used to treat mild to moderate pain, including headaches, toothaches, and post-surgical pain
• Effective in reducing discomfort caused by inflammation and minor injuries
• Can be used to ease pain from minor burns, insect bites, or skin irritations
• Provides temporary relief from nerve-related pain
• Used as an antipyretic to break fever cycles

In the case of an overdose of Paracetamol, prompt medical attention is necessary. Symptoms may include nausea, vomiting, and abdominal pain. Liver damage can occur, requiring immediate treatment with acetylcysteine. For Lidocaine injection overdose, initial symptoms include agitation, confusion, and seizures. Severe cases can lead to cardiac arrest, requiring immediate medical intervention and close monitoring of vital signs and ECG.

In the case of a missed dose of Paracetamol, take the missed dose as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. In the case of a missed dose of Lidocaine injection, consult your healthcare professional immediately for advice, as the administration of this medication requires medical supervision. It is important to not self-administer missed doses without proper guidance.

To administer Paracetamol and Lidocaine injection, clean the injection site with an alcohol swab, insert the needle at a 90-degree angle, and slowly inject the medication, ensuring the entire dose is delivered, then safely dispose of the used needle and syringe in a designated sharps container.

Following are the conditions/situations when Paracetamol and Lidocaine injection should not be used:

• Allergic reactions Not to be used if the patient has a known allergy or hypersensitivity to paracetamol or lidocaine.
• Liver impairment Paracetamol should be avoided or used with extreme caution in patients with severe liver disease or liver impairment.
• Methemoglobinemia Lidocaine injection should be avoided in patients with a history of methemoglobinemia or glucose-6-phosphate dehydrogenase (G6PD) deficiency.
• Heart conditions Lidocaine injection should be used with caution in patients with heart problems, such as heart block, heart failure, or irregular heart rhythms.
• Local infection Lidocaine injection should not be administered at sites of local infection or open wounds.
• Breastfeeding Lidocaine may pass into breast milk, so it should be used with caution in breastfeeding mothers.
• Pediatric use Paracetamol and Lidocaine injections should not be used in children without medical supervision and proper dosage calculations.

The side effects of Paracetamol may include:

• Allergic reactions (such as skin rash, itching, or hives)
• Liver damage (in rare cases)
• Nausea and vomiting
• Stomach pain
• Fatigue and weakness
• Increased sweating
• Unusually rapid heartbeat
• Numbness or tingling around the injection site
• Temporary muscle twitching
• Dizziness or lightheadedness
• Nausea and anxiety
• Confusion
• Ringing in the ears (tinnitus)
• Seizures (in rare cases)
• Allergic reactions (skin rash, itching, or difficulty breathing)

Following are the precautions and warnings for Paracetamol, Lidocaine injection:

• Not recommended for patients with severe liver or kidney disease, as it may cause further damage and affect drug metabolism.
• Should be used with caution in patients with heart problems, as Lidocaine can affect heart rhythm.
• Do not exceed the recommended dosage, as Paracetamol overdose can lead to severe liver damage.
• Lidocaine may cause temporary numbness and tingling at the injection site, but if it persists or spreads, seek medical attention.
• Avoid using this medication if you have a known allergy to Paracetamol or Lidocaine or any related compounds.
• This medication should be administered by trained medical professionals only, and the injection site should be carefully chosen to avoid nerve damage.
• Inform your doctor if you are pregnant, breastfeeding, or have any other medical conditions before using this injection.

Following are the drug interactions for Paracetamol and Lidocaine Injection:

• Paracetamol may increase the risk of liver damage when taken with other potentially hepatotoxic medications, such as alcohol, certain antibiotics, and antiepileptic drugs.
• It can also interact with warfarin and other anticoagulants, affecting blood clotting.
• Lidocaine may interact with other local anesthetics, increasing the risk of adverse effects and toxicity.
• Lidocaine may enhance the effects of muscle relaxants and general anesthetics.
• Caution is advised when using Lidocaine with Class I antiarrhythmic drugs, as it may affect cardiac conduction.
• It can also interact with certain antibiotics, such as ampicillin, potentially reducing the effectiveness of the antibiotic.
• Lidocaine metabolism can be affected by drugs like cimetidine, potentially leading to increased plasma concentrations of Lidocaine.

Following are the food interactions for this:

• Avoid excessive alcohol consumption while taking Paracetamol, as it can increase the risk of liver damage, especially with long-term use.
• Grapefruit juice may slightly reduce the absorption of Paracetamol, but this interaction is not considered clinically significant.
• Fatty meals can delay the absorption of Paracetamol, potentially affecting its onset of action.
• Maintain a balanced diet to support overall health and avoid interactions with Paracetamol.
• Lidocaine injection does not have significant food interactions.
• However, it's best to avoid alcohol as it can affect the liver's ability to metabolize Lidocaine, potentially leading to increased side effects.
• Ensure adequate hydration and a healthy diet to support overall well-being during Lidocaine treatment.

Paracetamol and Lidocaine injection storage and disposal guidelines should be strictly followed for safety. Store the medications in a cool, dry place, preferably at room temperature (around 25°C), away from direct sunlight and moisture exposure. Keep the lid tightly sealed to maintain sterility and prevent contamination. Avoid extreme temperatures by not storing near heat sources or in the refrigerator. Always check the expiration date, and do not use the medication if it is expired. Dispose of any unused or expired injections responsibly; do not throw them into the trash or pour them down the drain. Contact your pharmacist or local waste management authority for guidance on proper disposal methods to ensure environmental safety. Keep all medications securely locked away from children to prevent accidental exposure.

Following are the quick tips for Paracetamol and Lidocaine Injection:

• Always follow your doctor's prescription for dosage and administration instructions.
• Check the expiry date before using the medication.
• Paracetamol can be taken with or without food, but a full glass of water should be consumed.
• Avoid alcohol consumption while taking Paracetamol.
• Lidocaine injection should be administered by a trained healthcare professional only.
• Inform your doctor if you have any allergies or medical conditions before receiving Lidocaine.
• Store the injection at room temperature, away from direct sunlight and moisture.
• Do not reuse needles or syringes; dispose of them safely after use.