Fexo-D (60/120mg) 10 Tablets

Fexofenadine and pseudoephedrine are combined in this medication to relieve symptoms associated with seasonal allergies and the common cold. Fexofenadine, a second-generation antihistamine, works by blocking histamine receptors, thereby reducing allergic reactions such as sneezing, itching, and runny nose. On the other hand, pseudoephedrine, a sympathomimetic amine, acts as a decongestant by stimulating alpha-adrenergic receptors in the nasal mucosa, leading to vasoconstriction and reduced congestion in the nasal passages. This combined approach helps alleviate the discomfort caused by allergies and colds.

Antihistamine, Decongestant.

Tablet

The following are the uses of pseudoephedrine, Fexofenadine Tablet:

• Used for temporarily relieving symptoms of sinus pressure, congestion, and pain.
• Used to reduce nasal congestion and promote sinus drainage.
• Used for providing relief from allergic reactions, particularly allergic rhinitis.
• Effective in reducing sneezing, runny nose, and itchy, watery eyes caused by allergies.
• Used for treating hives and skin itching related to certain skin conditions.
• Helps alleviate symptoms of the common cold, such as nasal congestion and sinus discomfort.
• Can be used to enhance athletic performance and promote alertness, but this use is not medically recommended.
• Used in certain cases to treat ear congestion and pressure associated with conditions like ear infections.

In the case of an overdose of pseudoephedrine and Fexofenadine Tablets, individuals may experience heightened side effects specific to each medication. For pseudoephedrine, this could include increased heart rate, elevated blood pressure, and restlessness. Fexofenadine overdose symptoms may involve drowsiness, dizziness, and headache. Promptly seek medical advice or attention if you suspect an overdose, and provide healthcare professionals with details of the medications involved.

In the case of a missed dose of pseudoephedrine, take it as soon as you remember, but if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. For Fexofenadine, if you miss a dose, take it as soon as you remember, but if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. It's important not to take extra medication to compensate for a missed dose, as this could lead to potential side effects.

To take Pseudoephedrine and Fexofenadine tablets, swallow the tablets whole with a full glass of water, following the prescribed dosage as directed by your healthcare provider; typically taken once daily, with or without food, ensuring you adhere to the recommended dosage instructions for optimal effectiveness.

Following are the conditions/situations when Pseudoephedrine and Fexofenadine Tablet should not be used:

• Avoid using this combination medication if you are allergic to either Pseudoephedrine or Fexofenadine or any other similar decongestants or antihistamines.
• Not suitable for individuals with severe high blood pressure, severe heart blood vessel disease, or severe heart disease.
• Should not be used if you have taken an MAO inhibitor in the past 14 days.
• Contraindicated in patients with narrow-angle glaucoma or urinary retention.
• Not recommended for individuals with kidney disease or liver disease.
• Do not use this medication if you have had a severe allergic reaction to a similar antihistamine in the past.
• Avoid using this medication if you have ever had a condition called bronchospasm, or if you have used a monoamine oxidase inhibitor (MAOI) in the past 14 days.

The side effects of Pseudoephedrine and Fexofenadine Tablet may include:

• Dry mouth or throat
• Drowsiness or fatigue
• Dizziness or lightheadedness
• Nausea or upset stomach
• Headache
• Insomnia or difficulty sleeping
• Nervousness or restlessness
• Increased heart rate or palpitations
• Increased blood pressure
• Sweating
• Blurred vision
• Rare allergic reactions such as rash, itching, or swelling

Following are the precautions and warnings for Pseudoephedrine, Fexofenadine Tablet:

• Avoid use if you have a known allergy to pseudoephedrine or fexofenadine or any other decongestants or antihistamines.
• Patients with high blood pressure, heart disease, diabetes, thyroid problems, or prostate issues should use with caution and consult a healthcare professional.
• May cause dizziness or drowsiness, so refrain from driving or operating heavy machinery until you know how the medication affects you.
• Do not consume alcohol while taking this medication as it may intensify side effects.
• Elderly patients may be more sensitive to the effects, especially heart-related issues and dizziness.
• Not recommended for use in children under 12 years of age without medical advice.
• If you are pregnant or breastfeeding, consult your doctor before use, as the potential risks may outweigh the benefits.

Following are the drug interactions for Pseudoephedrine and Fexofenadine:

• Pseudoephedrine may interact with other stimulants or amphetamines, increasing blood pressure and heart rate.
• Drugs that lower blood pressure, such as beta-blockers, can have their effects reduced by Pseudoephedrine.
• Fexofenadine may decrease the absorption of certain antifungal medications like ketoconazole and itraconazole.
• Antacids containing aluminum or magnesium can reduce the absorption of Fexofenadine if taken simultaneously.
• Erythromycin, a macrolide antibiotic, can increase the concentration of Fexofenadine in the body.
• Fexofenadine should be used cautiously with sedatives and alcohol, as it may enhance their effects.
• Drugs that are strong inhibitors of CYP3A4 enzyme, such as ketoconazole and ritonavir, can increase Fexofenadine levels in the body.
• Grapefruit juice should be avoided as it can increase the concentration of Fexofenadine, potentially leading to increased side effects.

Following are the food interactions for Pseudoephedrine and Fexofenadine Tablet:

• Grapefruit and grapefruit juice should be avoided as they may inhibit the metabolism of pseudoephedrine, potentially leading to increased side effects like high blood pressure and increased heart rate.
• Avoid consuming large amounts of caffeine while taking pseudoephedrine as it can increase the stimulant effect, causing nervousness and rapid heartbeat.
• Fexofenadine can be taken without regard to meals, but some studies suggest that taking it with a meal may slightly increase absorption.
• Alcohol can be consumed with both pseudoephedrine and fexofenadine, but it's best to limit alcohol intake as it may increase the risk of side effects like dizziness and drowsiness.
• Avoid eating or drinking large amounts of dairy products, antacids, or high-potyassium foods close to taking fexofenadine as they can potentially interfere with absorption.
• No significant food interactions are known to affect the effectiveness of fexofenadine negatively.
• Always ensure you are well-hydrated when taking these medications, and consult your healthcare provider for personalized advice regarding dietary considerations.

Pseudoephedrine and Fexofenadine Tablets should be stored in a secure and dry location, preferably in a medicine cabinet or a designated storage area, away from direct sunlight, moisture, and extreme temperatures. It is crucial to keep the tablets in their original packaging, ensuring the container is tightly sealed to maintain their integrity. When disposing of unused or expired medication, it is essential to follow local guidelines and regulations. Do not flush the tablets down the toilet or discard them in regular household waste. Instead, utilize designated medication disposal programs or contact your local pharmacy or healthcare facility for guidance on safe disposal methods. Keep the medication out of children's reach to prevent accidental consumption, and always exercise caution when handling and storing these tablets.

Following are the quick tips for pseudoephedrine and Fexofenadine Tablet:

• Consult your healthcare provider before use, especially if you have a medical condition or are taking other medications.
• Take the medication as directed; do not exceed the recommended dosage.
• Swallow the tablet whole with water, do not crush or chew.
• Avoid taking with fruit juices, especially grapefruit juice, as it may affect absorption.
• If you experience dizziness, avoid driving or operating heavy machinery.
• Store in a cool, dry place, away from direct sunlight and moisture.
• Keep a record of your symptoms and progress while taking the medication.