FLEXZEN PLUS TAB

Paracetamol primarily acts by inhibiting the synthesis of prostaglandins in the central nervous system, effectively reducing pain and fever. Serratiopeptidase exerts its anti-inflammatory effects by breaking down fibrin, a protein involved in inflammation, and promoting the removal of inflammatory mediators. Diclofenac Potassium, a non-steroidal anti-inflammatory drug (NSAID), works by inhibiting cyclooxygenase (COX) enzymes, particularly COX-2, which reduces the production of prostaglandins responsible for pain, inflammation, and fever. This combination's synergistic effect aims to alleviate pain, reduce inflammation, and provide symptomatic relief by targeting multiple pathways involved in the pain and inflammatory responses.

Analgesic, Proteolytic Enzyme, NSAID.

Tablet

The following are the uses of Paracetamol, Serratiopeptidase, Diclofenac Potassium Tablet:

• Used for relieving mild to moderate pain such as headaches, toothaches, and post-vaccination fever.
• Used to reduce inflammation and provide relief from swelling and pain associated with various conditions like sprains and strains.
• Effective in managing symptoms of rheumatoid arthritis, osteoarthritis, and other joint-related issues.
• Helps lower high body temperature and reduce fever.
• Provides comfort and promotes healing in cases of minor injuries and post-operative pain.
• Assists in alleviating discomfort from sore throat, cold, and flu symptoms.
• Can be used to ease menstrual cramps and mild to moderate pain during periods.
• Aids in reducing pain and inflammation in conditions like back pain and muscle aches.

In the case of an overdose of Paracetamol, Serratiopeptidase, and Diclofenac Potassium Tablet, it is crucial to seek medical assistance promptly. Symptoms may include abdominal pain, nausea, and potential liver damage. Immediate treatment involves inducing vomiting or performing gastric lavage to remove the excess medication. Medical professionals will also monitor and manage any adverse effects on the liver and gastrointestinal system.

In the case of a missed dose of Paracetamol, Serratiopeptidase, and Diclofenac Potassium Tablet, it is recommended to take the medicine as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one, as this may increase the risk of side effects. Consult your healthcare provider if you have any concerns or if you frequently miss doses.

To take the Paracetamol, Serratiopeptidase, and Diclofenac Potassium Tablet, swallow the tablet whole with a glass of water; it is recommended to take it after a meal to prevent stomach irritation, and follow the dosage instructions provided by your healthcare professional, typically taken once or twice a day as advised.

Here are the conditions and situations when Paracetamol, Serratiopeptidase, and Diclofenac Potassium Tablet should not be used:

• Should not be used in individuals with a known allergy to any of its components, including Paracetamol, Serratiopeptidase, and Diclofenac Potassium.
• Contraindicated in patients with a history of gastrointestinal bleeding or perforation associated with previous NSAID (Non-Steroidal Anti-Inflammatory Drugs) therapy.
• Not suitable for patients with severe heart failure or conditions that may lead to heart failure.
• Should be avoided in individuals with active peptic ulcer or a history of recurrent peptic ulcers.
• Not recommended for patients with severe kidney or liver impairment.
• Contraindicated during the third trimester of pregnancy due to potential fetal risks.
• Should not be used in individuals with severe dehydration or conditions causing fluid retention.
• Avoid using this medication if you have a history of asthma or allergic reactions triggered by Aspirin or other NSAIDs.
• Not suitable for individuals with bleeding disorders or those on anticoagulant therapy.
• Should be used with caution in elderly patients, as they may be more susceptible to side effects.

The side effects of Paracetamol, Serratiopeptidase, and Diclofenac Potassium Tablet may include:

• Nausea and vomiting
• Stomach pain or discomfort
• Diarrhea
• Dizziness or vertigo
• Skin rashes or itching
• Increased blood pressure
• Gastrointestinal bleeding (in rare cases)
• Allergic reactions (e.g., swelling of the face, lips, or throat)

Following are the precautions and warnings for Paracetamol, Serratiopeptidase, and Diclofenac Potassium Tablet:

• This medication should be used with caution in patients with liver or kidney impairment, as it may require dosage adjustments or close monitoring.
• Avoid excessive alcohol consumption while taking this medication, as it may increase the risk of liver damage.
• Do not take this medication if you have a history of allergic reactions to Paracetamol, Serratiopeptidase, or Diclofenac.
• Patients with asthma, peptic ulcers, or gastrointestinal bleeding should use this medication with caution and under medical supervision.
• It is important not to exceed the recommended dosage, as it may lead to serious side effects, including gastrointestinal bleeding and liver toxicity.
• Pregnant and breastfeeding women should consult their doctor before taking this medication, as it may have potential risks for the fetus or infant.
• If you are taking other medications, especially blood thinners or corticosteroids, inform your healthcare provider to avoid potential drug interactions.
• Discontinue use and seek medical attention if you experience severe skin reactions, difficulty breathing, or unusual bleeding/bruising while on this medication.

Following are the drug interactions for Paracetamol, Serratiopeptidase, and Diclofenac Potassium Tablet:

• Paracetamol may interact with other central nervous system (CNS) depressants like opioids, increasing the risk of respiratory depression and sedation.
• Serratiopeptidase can increase the absorption of certain antibiotics, such as amoxicillin, potentially requiring dosage adjustments.
• Diclofenac can reduce the effectiveness of antihypertensive medications, including ACE inhibitors and beta-blockers.
• Concomitant use with other non-steroidal anti-inflammatory drugs (NSAIDs) may increase the risk of gastrointestinal bleeding and kidney problems.
• Paracetamol may prolong the effects of anticoagulants (e.g., warfarin), requiring close monitoring of blood clotting parameters.
• Serratiopeptidase may enhance the blood-thinning effects of antiplatelet drugs like aspirin, necessitating dosage adjustments.
• Diclofenac can increase the risk of bleeding when used with anticoagulants and antiplatelet agents, and regular monitoring is advised.
• Some medications, such as corticosteroids, may mask the signs of infection when used with this combination, requiring caution.

Following are the food interactions for Paracetamol, Serratiopeptidase, Diclofenac Potassium Tablet:

• Grapefruit juice should be avoided as it may increase the levels of Diclofenac in the blood, leading to potential side effects.
• Alcohol consumption should be minimized or avoided as it can increase the risk of gastrointestinal bleeding and liver toxicity, especially with Diclofenac.
• Avoid fatty or greasy foods as they may delay the absorption of Paracetamol and Serratiopeptidase, affecting their effectiveness.
• Caffeine-rich beverages like coffee and energy drinks may interact with Diclofenac, potentially reducing its pain-relieving effects.
• Spicy foods might irritate the stomach lining and exacerbate the risk of gastrointestinal issues, especially with regular use of Diclofenac.
• Dairy products, particularly milk, can potentially reduce the absorption of Diclofenac, so it's best to separate them by a few hours.
• Antioxidant-rich foods like berries, nuts, and dark chocolate might enhance the anti-inflammatory effects of Serratiopeptidase.
• Garlic and ginger, known for their anti-inflammatory properties, could potentially complement the effects of Diclofenac and Serratiopeptidase.

Paracetamol, Serratiopeptidase, Diclofenac Potassium Tablet should be stored in a secure and dry location, preferably at room temperature (68°F to 77°F or 20°C to 25°C), away from excess heat, moisture, and direct sunlight. Keep the tablets in their original container, tightly sealed, to maintain their integrity and effectiveness. It is crucial to ensure that the medication is stored out of sight and reach of children and pets to prevent accidental consumption. When disposing of unused or expired tablets, do not throw them in the trash or flush them down the toilet. Instead, follow local guidelines for medication disposal or consult your pharmacist for environmentally safe disposal options. Proper storage and disposal practices help maintain the medication's efficacy and contribute to environmental responsibility.

Following are the quick tips for Paracetamol, Serratiopeptidase, and Diclofenac Potassium Tablet:

• Consult a doctor before use, especially if you have allergies, liver/kidney issues, or are pregnant/breastfeeding.
• Take the tablet with a full glass of water, preferably with or after food.
• Do not crush or chew the tablet; swallow it whole.
• Maintain a gap of at least 4-6 hours between doses to prevent overdose.
• Avoid alcohol consumption as it may increase the risk of liver damage.
• If you experience prolonged or severe side effects, seek medical attention immediately.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.