Floramex (2mg) 20 Capsules

Loperamide 2mg capsules primarily work by slowing down the movement of the gut. Its mechanism of action involves binding to opioid receptors in the gastrointestinal tract, particularly in the myenteric plexus. By activating these receptors, loperamide reduces intestinal motility, which leads to decreased peristalsis and increased transit time of intestinal contents. This action helps to reduce the frequency of bowel movements and allows more time for water absorption, resulting in firmer stools and improved stool consistency. Additionally, loperamide enhances the tonic contraction of the anal sphincter, contributing to better bowel control.

Loperamide 2mg

Antidiarrheal

Capsule

The following are the uses of Loperamide 2mg Capsule:

• Used for effectively controlling acute diarrhea and reducing stool frequency.
• Used for treating sudden diarrhea associated with bacterial or viral infections.
• Used for managing chronic diarrhea in conditions like irritable bowel syndrome (IBS).
• Used for reducing intestinal secretion and slowing intestinal motility.
• Used for providing symptomatic relief from diarrhea, including traveler's diarrhea.
• Used for helping restore the body's fluid and electrolyte balance.
• Used for its ability to inhibit intestinal fluid and electrolyte secretion.

In the case of an overdose of Loperamide 2mg Capsules, individuals may experience severe gastrointestinal symptoms such as nausea, vomiting, abdominal pain, and constipation. More serious effects can include irregular heartbeat, severe drowsiness, and even loss of consciousness. Prompt medical intervention is necessary, as healthcare professionals may administer activated charcoal to absorb the excess medication and provide supportive care to manage symptoms until the drug is eliminated from the body.

In the case of a missed dose of Loperamide 2mg Capsule, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track with your medication regimen. Consult your healthcare provider if you have any concerns or questions about managing missed doses.

To take Loperamide 2mg Capsule, swallow the capsule whole with a full glass of water, ensuring you follow the prescribed dosage as directed by your healthcare provider, typically taken after each loose stool, with a maximum daily dose not exceeding 16mg.

Here are the conditions or situations when Loperamide 2mg Capsule should not be used:

• Avoid using if you have an allergy to Loperamide or any other similar medications.
• Not suitable for individuals with acute dysentery, diarrhea caused by toxins or infections like Salmonella or E. coli.
• Should not be used if you have a blockage in the intestines or a condition known as megacolon.
• Contraindicated in patients with ulcerative colitis or a sudden worsening of Crohn's disease.
• Not recommended for children under 2 years of age without medical advice.
• Avoid using if you have a fever or if your diarrhea is accompanied by blood or mucus in the stool.
• Do not take if you have recently taken antibiotics or have a history of antibiotic-associated diarrhea.

The side effects of Loperamide 2mg Capsule may include:

• Constipation
• Dizziness
• Nausea
• Stomach pain
• Fatigue or drowsiness
• Dry mouth
• Skin rash
• Difficulty urinating

Following are the precautions and warnings for Loperamide 2mg Capsule:

• Not recommended for individuals with acute dysentery, where there may be blood in the stool, or in cases of amoebic dysentery.
• Loperamide should be used with caution in patients with liver disease, as it is primarily metabolized in the liver.
• This medication may cause dizziness or drowsiness; patients should be cautious when driving or operating heavy machinery.
• Avoid alcohol consumption while taking Loperamide, as it may intensify these effects.
• Do not exceed the recommended dosage, as it may lead to severe adverse effects, including paralysis and cardiac arrest.
• Children under 12 years old should not be given Loperamide unless prescribed by a healthcare professional.
• Elderly patients may be more sensitive to the effects of Loperamide, and dosage adjustments might be necessary.
• If symptoms persist or worsen, or if abdominal pain or fever develops, consult a healthcare provider immediately.

Following are the drug interactions for Loperamide 2mg Capsule:

• Alcohol and other central nervous system depressants can increase sedation when taken with Loperamide.
• Macrolide antibiotics (e.g., erythromycin) and protease inhibitors (e.g., ritonavir) may inhibit the metabolism of Loperamide, leading to increased drug levels and potential toxicity.
• Cimetidine and other CYP3A4 inhibitors can reduce the metabolism of Loperamide, resulting in higher blood concentrations.
• Concomitant use with quinidine or ritonavir may increase Loperamide's effects and risk of adverse reactions.
• Opioid pain medications can interact, causing respiratory depression and sedation.
• Avoid using with other medications that can cause constipation, as it may worsen this side effect.
• Loperamide may reduce the absorption of certain HIV medications, such as didanosine.

Following are the food interactions for Loperamide 2mg Capsule:

• Avoid consuming grapefruit and grapefruit juice as they may decrease the metabolism of Loperamide, leading to increased drug levels in the body and potentially causing adverse effects.
• Alcohol consumption should be limited or avoided as it may worsen gastrointestinal symptoms and decrease the effectiveness of Loperamide in controlling diarrhea.
• Dairy products like milk and cheese can be consumed but may not provide relief from diarrhea as Loperamide does not treat diarrhea caused by lactose intolerance.
• Spicy foods should be avoided as they can irritate the digestive system and potentially trigger or worsen diarrhea.
• High-fiber foods like whole grains, legumes, and fruits should be consumed moderately as they can affect the absorption of Loperamide.
• Staying hydrated by drinking plenty of fluids, especially water, is crucial to replace lost fluids during diarrhea.
• It is advisable to follow a bland diet, including foods like rice, toast, and bananas, which are gentle on the digestive system during diarrhea.

Loperamide 2mg Capsules should be stored in a cool, dry place, preferably at room temperature between 20-25°C (68-77°F). Protect the capsules from light and moisture by keeping them in their original packaging or a tightly sealed container. Do not store in the bathroom or near sinks as exposure to moisture can affect the medication. Always check the expiration date, and dispose of expired capsules promptly. Proper disposal is crucial; do not throw them into the garbage or flush down the toilet. Contact your pharmacist or local waste disposal company for guidance on safe disposal methods. Keep this medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Loperamide 2mg Capsule:

• Consult your doctor for the right dosage and duration, as individual needs may vary.
• Swallow the capsule whole with a full glass of water for effective absorption.
• Avoid crushing, chewing, or opening the capsule as it may affect its effectiveness.
• Take the capsule as directed; do not increase or decrease the dosage without medical advice.
• Inform your doctor about all medications you are taking to prevent potential interactions.
• Store the capsules in a cool, dry place, away from direct sunlight and moisture.
• Do not take Loperamide if you have a known allergy to any of its ingredients.