Fluanxol (0.5mg) 10 Tablets

Flupenthixol's primary mechanism of action is its strong antagonism of dopamine D1 and D2 receptors, particularly in the mesolimbic and mesocortical pathways of the brain. It blocks these dopamine receptors, leading to a reduction in dopamine-mediated neurotransmission. This action is thought to be responsible for the antipsychotic effects of flupenthixol, as it helps to regulate dopamine activity, which is often dysregulated in various psychiatric disorders. Additionally, flupenthixol has mild anti-adrenergic and anti-serotonergic properties, but these are considered less significant in comparison to its dopamine receptor blockade. The overall effect is thought to contribute to the improvement of psychotic symptoms and mood stabilization in patients with schizophrenia and other psychotic disorders.

Flupenthixol

Antipsychotic/Antidepressant

Tablet

The following are the uses of Flupenthixol Tablet:

• Used for managing symptoms of schizophrenia, helping patients cope with delusions, hallucinations, and thought disorders.
• Used for treating chronic mental health conditions like schizoaffective disorder, offering long-term symptom control.
• Used for alleviating severe depression, particularly when other antidepressants haven't been effective.
• Used for managing behavioral problems in patients with dementia, though not a first-line treatment.
• Used for stabilizing mood in bipolar disorder, particularly during depressive episodes.
• Used for controlling aggression and violent behavior in individuals with personality disorders.
• Used for supporting patients transitioning from inpatient to outpatient care, aiding in symptom management.
• Used for reducing anxiety and agitation in certain mental health conditions, providing a calming effect.

In the case of an overdose of Flupenthixol Tablets, individuals may experience severe side effects and symptoms. The consequences can include a significant drop in blood pressure, leading to dizziness and fainting. Additionally, the person may exhibit neurological signs such as tremors, rigidity, and abnormal involuntary movements. It is crucial to seek immediate medical assistance if an overdose is suspected, as prompt treatment can help manage these symptoms and prevent potential complications.

In the case of a missed dose of Flupenthixol Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare professional for advice on how to safely adjust your dosage and get back on track with your treatment plan.

To take Flupenthixol Tablet, place the tablet in your mouth and swallow it whole with a glass of water, preferably in the morning or as directed by your healthcare professional, ensuring you follow the prescribed dosage and schedule provided by your doctor.

Here are the situations when Flupenthixol Tablet should not be used:

• Should not be used in patients with a known hypersensitivity or allergy to Flupenthixol or any of the excipients in the tablet.
• Contraindicated in patients with severe central nervous system depression or comatose states.
• Not recommended for individuals with untreated narrow-angle glaucoma.
• Should be avoided in patients with severe liver impairment or active liver disease.
• Contraindicated during the acute recovery period after a myocardial infarction (heart attack).
• Not suitable for patients with a history of blood disorders or bone marrow depression.
• Should not be used in patients with known pheochromocytoma.
• Contraindicated in patients with severe hypotension (low blood pressure).
• Not recommended for individuals with severe depression or suicidal tendencies without proper medical supervision.

The side effects of Flupenthixol Tablet may include:

• Dry mouth
• Blurred vision
• Constipation
• Dizziness
• Restlessness
• Sleep disturbances
• Skin rashes
• Muscle stiffness

Following are the precautions and warnings for Flupenthixol Tablet:

• Not suitable for individuals with a known hypersensitivity or allergy to Flupenthixol or any of its excipients.
• Requires caution in patients with a history of epilepsy or other seizure disorders, as it may lower the seizure threshold.
• Should be used with caution in individuals with cardiovascular disease, as it may affect heart rate and blood pressure.
• Patients with liver or kidney impairment may require dosage adjustments, and regular monitoring of liver and kidney function is advised.
• Elderly patients may be more susceptible to side effects, and close monitoring is necessary.
• Not recommended for children and adolescents under 18 years of age, as safety and efficacy have not been established.
• Flupenthixol may cause drowsiness and blurred vision, so patients should avoid driving or operating heavy machinery until they know how the medication affects them.

Following are the drug interactions for Flupenthixol Tablet:

• Alcohol and CNS depressants (e.g., benzodiazepines, opioids) may enhance the sedative effects of Flupenthixol, leading to increased drowsiness and impaired motor skills.
• Flupenthixol can interact with antihypertensive medications, causing a potential drop in blood pressure. Close monitoring is required.
• The effectiveness of Flupenthixol may be reduced when used with anticholinergic drugs, and it may increase the risk of side effects.
• Anticonvulsants like phenytoin and carbamazepine can decrease the plasma levels of Flupenthixol, possibly requiring dose adjustments.
• Lithium, when used with Flupenthixol, may increase the risk of neuroleptic malignant syndrome, a rare but serious side effect.
• Anticoagulants such as warfarin may have their effects altered by Flupenthixol, requiring close monitoring of coagulation parameters.
• Caution is advised when combining Flupenthixol with medications that prolong the QT interval, as it may further increase the risk of cardiac arrhythmias.

Following are the food interactions for Flupenthixol Tablet:

• Consumption of grapefruit or grapefruit juice should be avoided as it can interfere with the drug's metabolism, leading to increased levels of Flupenthixol in the body.
• Alcohol should be used with caution as it may enhance the sedative effects of Flupenthixol, causing excessive drowsiness and dizziness.
• Foods high in tyramine, such as aged cheeses, cured meats, and fermented foods, should be avoided as they may interact with Flupenthixol and increase the risk of high blood pressure.
• Caffeine intake should be monitored as it can exacerbate nervousness and restlessness, which are potential side effects of Flupenthixol.
• Avoid excessive salt or sodium-rich foods, as they may counteract the blood pressure-regulating effects of Flupenthixol.
• Consuming high-fat meals may slightly delay the absorption of Flupenthixol, but it is generally well-tolerated with food.
• There is no specific dietary restriction, but maintaining a balanced diet is advisable to support overall health while taking this medication.
• Always follow the advice of your healthcare professional regarding any specific dietary adjustments needed during Flupenthixol therapy.

Flupenthixol Tablets should be stored in a secure and dry location, preferably in their original packaging, to maintain their integrity and potency. Keep the tablets away from heat, moisture, and direct sunlight, as these conditions can degrade the medication. Ensure the container is tightly sealed to prevent exposure to air and humidity. Always check the expiration date, and never use the medication beyond this date. When disposing of unused or expired tablets, do not throw them in the trash or flush them down the toilet. Instead, follow local guidelines for pharmaceutical waste disposal or consult a healthcare professional for advice on safe disposal methods. Keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Flupenthixol Tablet:

• Take the tablet as directed by your doctor; do not crush, chew, or break it.
• Ensure you understand the dosage instructions and duration of treatment.
• Flupenthixol may be taken with or without food, but be consistent with your routine.
• Avoid alcohol consumption while taking this medication as it may intensify side effects.
• Inform your doctor about all medications you are taking to prevent potential interactions.
• Regular follow-ups with your healthcare provider are essential to monitor your progress.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.