FLUEZE SACHETS (10S)

Pseudoephedrine, Mepyramine, and Pheniramine work synergistically in this combination. Pseudoephedrine, a sympathomimetic amine, primarily acts as a potent alpha-adrenergic receptor agonist, leading to vasoconstriction of the blood vessels in the nasal mucosa. This action reduces nasal congestion and promotes sinus drainage. Mepyramine and Pheniramine are both first-generation antihistamines that block H1-receptor sites, preventing the release of histamine, which is responsible for allergic symptoms such as sneezing, itching, and runny nose. By combining these mechanisms, this sachet formulation provides comprehensive relief from nasal congestion, sinus pressure, and allergic reactions.

Sympathomimetic and Antihistamine

powder

The following are the uses of Pseudoephedrine, Mepyramine, Pheniramine Sachet:

• Used for temporarily relieving symptoms of sinus pressure, congestion, runny nose, and sneezing due to the common cold, hay fever, or other upper respiratory allergies.
• Used for providing temporary relief from sinus congestion and pressure, reducing the symptoms of sinus headache.
• Used for treating nasal congestion and sinus pain associated with various respiratory conditions.
• Used for reducing inflammation and congestion in the nasal passages, providing relief from symptoms of allergic reactions.
• Used for alleviating symptoms of allergic rhinitis, including sneezing, itching, and runny nose.
• Used for easing discomfort and congestion caused by sinusitis or nasal inflammation.
• Used for promoting sinus drainage and reducing facial pain and pressure associated with sinus congestion.

In the case of an overdose of Pseudoephedrine, Mepyramine, and Pheniramine Sachet, individuals may experience a range of symptoms. These can include increased heart rate, elevated blood pressure, restlessness, and in severe cases, seizures or loss of consciousness. Prompt medical intervention is necessary, as treatment may involve supportive care, monitoring vital signs, and managing any complications that arise from the overdose. It is important to seek professional advice and not delay treatment.

In the case of a missed dose of Pseudoephedrine, Mepyramine, or Pheniramine Sachet, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this may increase the risk of side effects. It is important to maintain a consistent dosing schedule for the medication to be most effective.

To use the Pseudoephedrine, Mepyramine, and Pheniramine Sachet, empty the contents of the sachet into a glass of water, stir well until completely dissolved, and drink the entire mixture once daily as directed by your healthcare provider, ensuring you follow the prescribed dosage instructions for effective relief.

Following are the conditions/situations when Pseudoephedrine, Mepyramine, Pheniramine Sachet should not be used:

• Not suitable for individuals with a known allergy or hypersensitivity to Pseudoephedrine, Mepyramine, Pheniramine, or any other decongestants or antihistamines.
• Should not be used in patients with narrow-angle glaucoma.
• Contraindicated in individuals with severe cardiovascular diseases, including severe high blood pressure, coronary artery disease, and cardiac arrhythmias.
• Not recommended for patients with an overactive thyroid (hyperthyroidism).
• Avoid in individuals with severe liver or kidney disease.
• Should not be used in patients with difficulty urinating due to an enlarged prostate or any other urinary retention issues.
• Contraindicated during pregnancy, especially in the first trimester, unless the potential benefits outweigh the risks.
• Not suitable for breastfeeding mothers, as these medications may pass into breast milk and harm the nursing infant.
• Avoid in children below 2 years of age due to the potential for serious side effects.

The side effects of Pseudoephedrine, Mepyramine, Pheniramine Sachet may include:

• Increased heart rate
• Dizziness or lightheadedness
• Nervousness or anxiety
• Insomnia
• Dry mouth
• Nausea and vomiting
• Difficulty in urination
• Skin rash or itching

Following are the precautions and warnings for Pseudoephedrine, Mepyramine, and Pheniramine Sachet:

• Individuals with known allergies to any of the active ingredients, including Pseudoephedrine, Mepyramine, or Pheniramine, should not use this medication.
• Patients with a history of heart-related conditions, high blood pressure, diabetes, or thyroid problems should exercise caution and consult a healthcare professional before use.
• Avoid alcohol consumption while taking this medication as it may increase side effects.
• Do not drive or operate heavy machinery if you experience drowsiness, dizziness, or blurred vision after taking this medication.
• This medication may cause urine to turn a dark color, which is a normal side effect.
• Consult a doctor if you are pregnant, planning to become pregnant, or breastfeeding before using this sachet.
• Keep out of reach of children and store in a cool, dry place.
• Do not exceed the recommended dosage and duration of use without medical advice.

Following are the drug interactions for Pseudoephedrine, Mepyramine, and Pheniramine Sachet:

• Alcohol and other central nervous system (CNS) depressants (e.g., benzodiazepines, opioids) may enhance the sedative effects of Mepyramine and Pheniramine, leading to increased drowsiness and impaired thinking.
• Monoamine oxidase inhibitors (MAOIs) should be avoided with Pseudoephedrine as they may increase blood pressure and the risk of cardiovascular events.
• Beta-blockers and other medications that increase blood pressure can have an additive effect with Pseudoephedrine, potentially causing hypertension.
• Antihistamines like Mepyramine and Pheniramine can reduce the effectiveness of medications used to treat asthma and chronic obstructive pulmonary disease (COPD).
• Pheniramine may increase the side effects of anticholinergic drugs, such as dry mouth, blurred vision, and urinary retention.
• Anticonvulsants and tricyclic antidepressants may interact with Mepyramine and Pheniramine, potentially increasing their sedative effects.
• Drugs that lower the seizure threshold, such as certain antidepressants and antipsychotics, may have their effects enhanced by Mepyramine and Pheniramine.

Following are the food interactions for Pseudoephedrine, Mepyramine, Pheniramine Sachet:

• Grapefruit juice should be avoided as it may interfere with the breakdown of Pseudoephedrine, leading to increased side effects like elevated blood pressure and heart rate.
• Alcohol consumption should be limited as it can cause excessive drowsiness and dizziness when combined with Mepyramine and Pheniramine.
• Caffeine intake should be monitored as it can enhance the stimulant effects of Pseudoephedrine, potentially causing nervousness and rapid heartbeat.
• Avoid high-sodium foods as Pseudoephedrine may increase sodium retention, affecting individuals with high blood pressure.
• Spicy foods may exacerbate symptoms of runny nose and congestion, so it's advisable to limit their consumption.
• Stay hydrated by drinking plenty of water to counteract the potential dehydrating effects of this medication.
• Consume a balanced diet to support overall health and immune function during treatment.
• Always consult a healthcare professional for personalized advice regarding dietary restrictions and interactions.

Pseudoephedrine, Mepyramine, and Pheniramine Sachets should be stored in a secure and controlled environment, preferably in a locked cabinet or a designated storage area with restricted access. Keep the sachets in their original packaging, ensuring they remain intact and uncontaminated. Store them in a cool, dry place, away from direct sunlight, excessive heat, or moisture, maintaining a consistent room temperature. Regularly check the expiration dates on the sachets and dispose of any expired or unused medication promptly. Proper disposal is crucial; do not flush or pour the contents down the drain. Contact your local pharmacist or healthcare provider for guidance on safe disposal methods. Always keep these medications out of the reach of children and pets to prevent accidental ingestion.

Following are the quick tips for Pseudoephedrine, Mepyramine, Pheniramine Sachet:

• Consult a healthcare professional for personalized advice on using the sachet.
• Ensure you understand the dosage instructions and duration of use.
• Take the medication as directed, without altering the dose or frequency.
• Stay well-hydrated while using the sachet to support overall health.
• Avoid operating heavy machinery or driving until you know how the medication affects you.
• If you have any medical conditions or are taking other medications, inform your doctor.
• Store the sachet in a cool, dry place, away from direct sunlight and moisture.