Flueze 100 Tablets

Pseudoephedrine, a sympathomimetic amine, acts by stimulating alpha-adrenergic receptors, leading to vasoconstriction and decreased blood flow to the nasal mucosa, thereby reducing congestion. Paracetamol, an analgesic and antipyretic, exerts its effects through inhibiting the synthesis of prostaglandins, which are involved in pain and inflammation. Mepyramine and Pheniramine, both H1-receptor antagonists, block the effects of histamine, providing relief from allergic symptoms by preventing the activation of histamine receptors in various tissues. This combination of active ingredients works synergistically to alleviate symptoms associated with allergic rhinitis, such as nasal congestion, sneezing, and itching.

Analgesic/Antipyretic and Antihistamine

Tablet

The following are the uses of Pseudoephedrine, Paracetamol, Mepyramine, Pheniramine Tablet:

• Used for relieving symptoms of cold, flu, and allergies, such as congestion, runny nose, sneezing, and itchy, watery eyes.
• Used to reduce fever and provide pain relief for mild to moderate aches and pains.
• Used to alleviate symptoms of allergic reactions, including itchy skin, hives, and skin rashes.
• Used to help control symptoms of sinusitis, such as nasal congestion and sinus pressure.
• Used to provide temporary relief from headache, toothache, and other minor body aches.
• Used to reduce discomfort from sore throat, particularly when it's caused by a cold or flu.
• Used to ease the symptoms of allergic rhinitis, including nasal and eye symptoms.

In the case of an overdose of Pseudoephedrine, Paracetamol, Mepyramine, and Pheniramine Tablets, individuals may experience a range of symptoms. These can include increased heart rate, dizziness, and gastrointestinal issues such as nausea and vomiting. In severe cases, seizures, respiratory distress, and even loss of consciousness may occur. Prompt medical intervention is essential, as healthcare professionals can provide supportive care and manage any life-threatening complications that may arise from the overdose.

In the case of a missed dose of Pseudoephedrine, Paracetamol, Mepyramine, and Pheniramine Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare provider for guidance on how to safely resume your medication regimen.

To take the Pseudoephedrine, Paracetamol, Mepyramine, and Pheniramine Tablet, swallow the tablet whole with a full glass of water; it is recommended to take this medication with food to prevent stomach upset. Follow the prescribed dosage instructions provided by your healthcare professional, typically taken every 4 to 6 hours, but not exceeding the maximum daily dosage within a 24-hour period.

Following are the conditions or situations when Pseudoephedrine, Paracetamol, Mepyramine, Pheniramine Tablet should not be used:

• Avoid use in individuals with a known allergy or hypersensitivity to any of the active ingredients, including Pseudoephedrine, Paracetamol, Mepyramine, or Pheniramine.
• Not recommended for patients with narrow-angle glaucoma.
• Contraindicated in individuals with severe cardiovascular disease, including hypertension, coronary artery disease, or a history of heart attack.
• Should not be used in patients with severe liver or kidney impairment.
• Avoid use during pregnancy, especially in the first trimester, unless the potential benefits outweigh the risks.
• Not suitable for infants or young children, as the dose needs to be adjusted according to age and weight.
• Do not use if you have a history of seizures or epilepsy, as Pseudoephedrine may increase the risk of seizures.
• Avoid using this medication if you have difficulty urinating or have an enlarged prostate, as it may worsen these conditions.
• Do not consume alcohol while taking this medication, as it may increase the risk of liver damage.
• Should not be used if you have taken an MAO inhibitor in the last 14 days, as it may cause a dangerous drug interaction.

The side effects of Pseudoephedrine, Paracetamol, Mepyramine, Pheniramine Tablet may include:

• Increased heart rate
• Elevated blood pressure
• Restlessness or insomnia
• Dizziness
• Nausea or upset stomach
• Dry mouth
• Blurred vision
• Difficulty urinating

Following are the precautions and warnings for Pseudoephedrine, Paracetamol, Mepyramine, and Pheniramine Tablet:

• This medication should be avoided in individuals with known allergies to any of the active ingredients or excipients in the tablet.
• Patients with high blood pressure, heart disease, diabetes, or an enlarged prostate should use this medication with caution and under medical supervision.
• Avoid alcohol consumption while taking this medication as it may intensify side effects.
• Do not drive or operate heavy machinery if you experience dizziness or drowsiness after taking the tablet.
• Consult a doctor if you have liver or kidney disease, as the dosage may need to be adjusted.
• This medication may cause urinary retention, so patients with urinary problems should use it with caution.
• Pregnant and breastfeeding women should consult their healthcare provider before taking this medication as it may pass into breast milk.
• Keep this medication out of reach of children and store it in a cool, dry place.

Following are the drug interactions for Pseudoephedrine, Paracetamol, Mepyramine, and Pheniramine Tablet:

• Alcohol and other central nervous system (CNS) depressants, such as benzodiazepines, opioids, or antipsychotics, can increase the sedative effects of Mepyramine and Pheniramine, leading to excessive drowsiness and impaired motor skills.
• Monoamine oxidase inhibitors (MAOIs) should be avoided with this combination due to the risk of severe hypertension and other cardiovascular side effects.
• Antihypertensive medications may have reduced effectiveness when taken with Pseudoephedrine, as it can increase blood pressure.
• Paracetamol may interact with anticoagulants (e.g., warfarin), potentially altering the blood-clotting process.
• Drugs that are metabolized by the liver, such as some anticonvulsants and antidepressants, may have altered levels when combined with Paracetamol.
• Using other sympathomimetic drugs with Pseudoephedrine may increase the risk of cardiovascular side effects and hypertension.
• Antihistamines like Mepyramine and Pheniramine can enhance the sedative effects of certain antidepressants and antipsychotics.

Following are the food interactions for Pseudoephedrine, Paracetamol, Mepyramine, and Pheniramine Tablet:

• Grapefruit and grapefruit juice should be avoided as they may affect the metabolism of the medication, potentially increasing the risk of side effects.
• Alcohol consumption should be minimized or avoided as it can increase the risk of liver damage when combined with Paracetamol.
• Caffeine-containing beverages like coffee and tea should be limited as Pseudoephedrine may increase caffeine's stimulant effects, leading to increased heart rate and blood pressure.
• Avoid consuming large amounts of chocolate, as it contains methylxanthines, which can enhance the stimulant effects of Pseudoephedrine.
• Foods rich in tyramine, such as aged cheeses, cured meats, and fermented foods, should be avoided as they can interact with Mepyramine and Pheniramine, potentially causing hypertension.
• Consuming a high-fat meal may slightly delay the absorption of Paracetamol, but it does not significantly affect its overall effectiveness.
• Ensure adequate fluid intake to maintain hydration while taking this medication, especially if you are experiencing fever or increased sweating.
• No specific food restrictions are associated with this medication, but maintaining a balanced diet is generally recommended for overall health.

Pseudoephedrine, Paracetamol, Mepyramine, and Pheniramine tablets should be stored in a cool, dry place, preferably at room temperature, ensuring protection from light and moisture. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent contamination. Avoid exposure to extreme temperatures by not storing them in bathrooms or near heat sources. Always check the expiration date, and if the tablets are expired or no longer needed, proper disposal is crucial. Do not dispose of them in sinks or toilets; instead, consult a pharmacist or healthcare professional for guidance on safe disposal methods. Keep these medications away from children to prevent accidental consumption.

Following are the quick tips for Pseudoephedrine, Paracetamol, Mepyramine, Pheniramine Tablet:

• Consult a healthcare professional before use, especially if you have a medical condition or are taking other medications.
• Take the tablet as directed by your doctor or pharmacist.
• Swallow the tablet whole with a full glass of water, do not crush or chew.
• Avoid consuming alcohol or operating heavy machinery until you know how the medication affects you.
• Do not exceed the recommended dosage, as it may lead to serious side effects.
• Store the medication in a cool, dry place, away from direct sunlight.
• Inform your doctor if you experience any unusual symptoms or allergic reactions.
• Dispose of expired or unused medication properly, do not flush down the toilet.