Fostrum (500mg) 12 Capsules

Cephradine 500mg capsule is a broad-spectrum antibiotic belonging to the cephalosporin class. It works by inhibiting the synthesis of bacterial cell walls, leading to the destruction of bacteria. Cephradine is effective against a wide range of Gram-positive and some Gram-negative bacteria, making it useful for treating infections such as respiratory tract infections (like bronchitis and pneumonia), urinary tract infections (UTIs), skin infections, and ear infections. It is commonly prescribed for both mild and moderate infections and can be used to treat conditions like streptococcal throat infections and uncomplicated skin and soft tissue infections. Cephradine is usually taken orally, with or without food, as prescribed by a healthcare provider. Proper dosing and adherence to the full course of treatment are essential to prevent antibiotic resistance.

Cephradine 500mg

antibiotic

Capsule

Following are the uses of Cephradine 500mg capsule:

• Used to treat a variety of bacterial infections, including respiratory tract infections like bronchitis, pneumonia, and streptococcal throat infections.
• Effective in managing urinary tract infections (UTIs), such as cystitis and pyelonephritis, caused by susceptible bacteria.
• Prescribed for skin and soft tissue infections, including cellulitis and impetigo.
• Can be used to treat ear infections (otitis media) caused by specific bacteria.
• Helps in treating bone and joint infections, such as osteomyelitis and septic arthritis.
• Effective for treating soft tissue infections in patients with conditions like diabetic foot infections.
• Often used for preventing and treating postoperative infections in certain surgical procedures.
• Used in treating infections of the upper respiratory tract, such as tonsillitis and pharyngitis, caused by susceptible organisms.
• Can be used in dental infections when a bacterial etiology is identified.

Following are the doses for Cephradine 500mg capsule:

• The usual adult dose is 250mg to 500mg every 6 to 12 hours, depending on the severity of the infection.
• For severe infections, the dose may be increased to 1g every 12 hours.
• The maximum dose should not exceed 4g per day.
• For pediatric patients, the dose is typically based on body weight, ranging from 25mg to 50mg per kg of body weight per day, divided into 2 to 4 doses.

In case of an overdose of Cephradine 500mg capsule, it is important to seek immediate medical attention. Symptoms of overdose may include nausea, vomiting, diarrhea, and potentially severe reactions like kidney dysfunction or blood clotting disorders. If an overdose is suspected, contact your healthcare provider, poison control center, or go to the nearest emergency room. Treatment will typically focus on managing symptoms and may involve supportive care, such as intravenous fluids or medications to counteract any adverse effects. There is no specific antidote for Cephradine, so prompt medical intervention is essential to prevent serious complications.

If you miss a dose of Cephradine 500mg capsule, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at once to make up for the missed dose, as this could increase the risk of side effects. If you are unsure about what to do or have any concerns, contact your healthcare provider for further guidance. It’s important to take the full course of the medication as prescribed, even if you feel better, to ensure the infection is fully treated.

To use Cephradine 500mg Capsule typically, it should be taken once or twice daily, with or without food. Swallow the capsule whole with a glass of water. Do not chew, crush, or break the capsule.

Following are the situations when Cephradine 500mg capsule should not be used:

• Should not be used in individuals with a known allergy to cephradine or other cephalosporins.
• Contraindicated in patients with a history of severe hypersensitivity (anaphylactic reactions) to penicillins or other beta-lactam antibiotics.
• Should not be used in newborns or infants under the age of 2 months, as safety has not been established.
• Not recommended in patients with a history of severe gastrointestinal conditions, such as colitis or inflammatory bowel disease, as it may exacerbate these issues.
• Contraindicated in patients with a history of blood clotting disorders or those on anticoagulant therapy due to an increased risk of bleeding.
• Should be avoided in patients with severe renal impairment unless adjusted dosing is carefully monitored.
• Should not be used during pregnancy unless clearly necessary, as it may pose potential risks to the developing fetus.
• Contraindicated in breastfeeding mothers unless no alternative antibiotic options are available.

Side effects of Cephradine 500mg capsule:

• Rash
• Diarrhea
• Nausea
• Vomiting
• Headache
• Dizziness
• Allergies
• Fatigue
• Abdominal pain
• Superinfection
• Jaundice
• Itching
• Swelling
• Anemia
• Nephrotoxicity

Following are the precautions and warnings for Cephradine 500mg capsule:

• Use with caution in patients with a history of hypersensitivity or allergic reactions to cephalosporins, penicillins, or other beta-lactam antibiotics due to the risk of cross-reactivity.
• Caution is advised in patients with renal impairment, as Cephradine is excreted by the kidneys and may require dosage adjustments.
• Prolonged use of Cephradine may lead to superinfection, including fungal infections or infections caused by resistant organisms.
• Use with caution in patients with gastrointestinal disorders, such as colitis or inflammatory bowel disease, as it may worsen these conditions.
• Cephradine may alter coagulation parameters, so caution is needed in patients on anticoagulants or those with bleeding disorders.
• This medication may cause dizziness, headache, or confusion, particularly in elderly or critically ill patients, so caution should be exercised during activities that require alertness.
• Cephradine should be used during pregnancy only when necessary, and only if the potential benefits outweigh the potential risks to the fetus.
• It is excreted in breast milk, so it should be used with caution in breastfeeding mothers.
• Monitor for any signs of allergic reactions, such as rash, swelling, or difficulty breathing, and seek immediate medical attention if these occur.
• Discontinue use and seek medical advice if severe diarrhea or abdominal cramping occurs, as this may be a sign of Clostridium difficile-associated diarrhea.

Following are the drug interactions for Cephradine 500mg capsule:

• May increase the anticoagulant effects of warfarin and other blood thinners, increasing the risk of bleeding.
• Concurrent use with aminoglycoside antibiotics (e.g., gentamicin) may increase the risk of nephrotoxicity.
• Probenecid may decrease the renal excretion of Cephradine, leading to higher blood levels and an increased risk of side effects.
• The use of Cephradine with diuretics like furosemide may increase the risk of kidney damage, particularly in patients with pre-existing renal conditions.
• Cephradine may reduce the effectiveness of live bacterial vaccines (e.g., typhoid vaccine).
• The use of Cephradine with oral contraceptives may reduce their effectiveness, so additional contraception methods may be recommended.
• The combination of Cephradine with certain antacids may reduce its absorption, leading to lower drug efficacy.
• Rifampin may decrease the effectiveness of Cephradine when used concurrently.
• Cephradine may interact with certain antiepileptic drugs (e.g., phenytoin), potentially affecting blood levels or efficacy.

Following are the food interactions for Cephradine 500mg capsule:

• No significant food interactions have been identified with Cephradine 500mg capsule.
• It can be taken with or without food, as directed by your healthcare provider.
• Taking Cephradine with a high-fat meal may delay its absorption slightly but does not significantly affect its overall effectiveness.
• Alcohol consumption should be avoided during treatment with Cephradine, as it can increase the risk of side effects such as gastrointestinal upset or liver toxicity.
• It is recommended to maintain adequate hydration, especially when taking Cephradine with other medications that may affect renal function.

Cephradine 500mg capsules should be stored in a cool, dry place, away from moisture and direct sunlight. Keep the medication in its original container and ensure that it is tightly closed to protect it from humidity and contamination. Do not store it in the bathroom or any place where it may be exposed to excessive heat or moisture. Keep it out of reach of children and pets. If you have expired or unused capsules, do not dispose of them in household trash or flush them down the toilet. Instead, consult your pharmacist or healthcare provider for advice on safe disposal methods, such as take-back programs or proper disposal at a local pharmacy. Proper disposal helps protect the environment and prevents accidental ingestion by children or pets.

Following are some quick tips for Cephradine 500mg capsule:

• Take the capsule exactly as prescribed by your healthcare provider, and complete the full course of treatment, even if you feel better.
• Cephradine can be taken with or without food, but it is important to follow your healthcare provider's specific instructions.
• Avoid alcohol while taking Cephradine to reduce the risk of side effects like gastrointestinal upset or dizziness.
• If you miss a dose, take it as soon as you remember, but skip the missed dose if it’s almost time for your next dose. Do not double up.
• Be mindful of any allergic reactions, such as rash or swelling, and seek immediate medical help if these occur.
• Ensure you stay hydrated, particularly if you are taking other medications that affect kidney function.
• Inform your doctor if you have any history of kidney or liver problems or if you are pregnant or breastfeeding.
• Store Cephradine in a cool, dry place, away from moisture, and out of reach of children.