Frendcogen (100mg) 20 Tablets

Frendcogen (100mg) 20 Tablets

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  • Manufacturer Friends Pharma (Pvt.) Ltd.
  • Generic Name Nimesulide

Healthwire Pharmacy Ratings & Reviews (1500+)

4.9/ 5
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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Description

    Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) that functions through a multi-step mechanism of action. First, it inhibits the enzyme cyclooxygenase-2 (COX-2), which is involved in the synthesis of prostaglandins, compounds that mediate inflammation, pain, and fever. By reducing prostaglandin production, nimesulide effectively decreases inflammation and alleviates pain. It also exhibits some selective action on COX-2, minimizing gastrointestinal side effects commonly associated with other NSAIDs. Nimesulide is particularly useful in treating acute pain, osteoarthritis, and dysmenorrhea.

  • Ingredients

    Nimesulide
  • Drug Class

    Nonsteroidal anti-inflammatory drug (NSAID)

  • Dosage Form

    Tablet
  • Uses

    This tablet is indicated in Painful inflammatory conditions including those associated with osteoarthritis, postoperative trauma, sports injuries, ear, nose and throat disorders, dental surgery, bursitis/tendinitis, thrombophlebitis, pharyngitis.
  • Dosage

    Frendcogen dosage for the indication of pain and inflammation, duration as needed:

    • Adults - 100 mg twice daily after meals.
    • Children - Not recommended.
  • In case of Overdose

    Overdose can cause liver toxicity and gastrointestinal issues. Immediate medical attention is required.

  • Missed Dose

    If you miss a dose, consume as soon as you remember. If it is close to the next feeding, skip the missed dose. Do not double up on doses.

  • How To Use

    Typically taken twice daily with or after meals. Follow the prescribed dose and duration of treatment.

  • When Not to Use

    Nimesulide should not be used if:

    • Hypersensitivity
    • Severe liver impairment
    • Active gastrointestinal bleeding
    • Renal impairment
  • Side Effects

    It cause Gastrointestinal toxicity.
  • Precautions & Warnings

    Should be used with caution in Patients with renal impairment (particularly elderly patients), congestive heart failure or cirrhosis or those patients who are volume or salt depleted
  • Drug Interactions

    The drug interactions with nimesulide include:

    • Anticoagulants (e.g., warfarin) – Can increase the risk of bleeding.
    • Other NSAIDs (e.g., ibuprofen) – Can increase the risk of gastrointestinal bleeding and ulceration.
  • Food Interactions

    For Nimesulide, food interactions that should be considered are:

    • Taking with food may help reduce gastrointestinal discomfort.
    • Avoid alcohol as it may increase the risk of gastrointestinal side effects.
  • Storage/Disposal

    Nimesulide should be stored at room temperature, away from moisture and heat. Keep it in its original container and out of reach of children. Dispose of expired or unused Nimesulide properly, following local disposal guidelines or using a drug take-back program.

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