Frilid-FR 60 Tablets

Fexofenadine and Montelukast, when combined in a tablet, work synergistically to provide relief from allergic reactions. Fexofenadine, a second-generation antihistamine, primarily blocks histamine receptors, preventing the release of histamine, which is responsible for allergic symptoms like itching and sneezing. On the other hand, Montelukast is a leukotriene receptor antagonist, targeting leukotrienes, potent inflammatory mediators that cause airway constriction and increased mucus production. By inhibiting the action of leukotrienes, Montelukast reduces inflammation in the airways, making it particularly effective in managing asthma and allergic rhinitis. Together, these mechanisms suppress the immune system's overreaction to allergens, offering comprehensive relief from various allergic symptoms.

Fexofenadine 120mg, Montelukast 10mg

Antihistamine, Leukotriene antagonist.

Tablet

The following are the uses of Fexofenadine 120mg, Montelukast 10mg Tablet:

• Used for relieving symptoms of seasonal allergies like hay fever, such as sneezing, runny nose, itchy and watery eyes.
• Used for treating allergic skin conditions, including chronic hives and itching.
• Used to prevent asthma symptoms, particularly for patients with exercise-induced asthma.
• Used to reduce inflammation in the airways, making breathing easier.
• Used to manage symptoms of allergic rhinitis throughout the year.
• Used to alleviate symptoms of nasal congestion and sinus pressure.
• Used for long-term control of asthma and reducing the frequency of asthma attacks.

In the case of an overdose of Fexofenadine 120mg and Montelukast 10mg tablets, it is important to recognize the potential symptoms. These may include drowsiness, rapid heartbeat, and dizziness. Prompt action should be taken, such as contacting a healthcare professional or a poison control center for guidance on appropriate treatment and management. Quick response can help mitigate the effects of the overdose and ensure the best possible outcome. It is crucial to act swiftly to address any potential health risks.

In the case of a missed dose of Fexofenadine 120mg, take the missed dose as soon as you remember, but if it's almost time for your next dose, skip the missed one and continue with your regular dosing schedule. For Montelukast 10mg, if you miss a dose, take it as soon as you remember, but if it's close to your next dose, skip the missed dose and resume your regular dosing schedule. It is generally recommended to take the medication at the same time each day to maintain consistent levels in your body. If you frequently miss doses, consult your healthcare provider for advice on how to improve your medication routine.

To take Fexofenadine 120mg and Montelukast 10mg tablets, swallow one tablet of each medication whole with a glass of water, preferably at the same time each day, as directed by your healthcare provider, and continue taking them regularly for the prescribed duration.

Following are the conditions/situations when Fexofenadine 120mg and Montelukast 10mg Tablet should not be used:

• Should not be used in individuals with a known allergy to Fexofenadine, Montelukast, or any other ingredients in the formulation.
• Not suitable for patients with severe kidney disease or end-stage renal disease.
• Should not be used in patients with a history of liver problems or liver disease.
• Contraindicated in individuals with a rare hereditary problem of galactose intolerance, severe lactase deficiency, or glucose-galactose malabsorption.
• Not recommended for children below 6 years of age due to the Fexofenadine component.
• Should not be used if you are currently taking certain specific medications, such as erythromycin, ketoconazole, or cimetidine, as these can interact with Fexofenadine.
• Avoid using this medication if you have a condition that causes slow digestion or problems with food absorption.

The side effects of Fexofenadine 120mg and Montelukast 10mg Tablet may include:

• Drowsiness
• Headache
• Nausea and vomiting
• Diarrhea
• Abdominal pain
• Dry mouth
• Fatigue and weakness
• Skin rash or itching

Following are the precautions and warnings for Fexofenadine 120mg, Montelukast 10mg Tablet:

• Do not take this medication if you are allergic to Fexofenadine, Montelukast, or any other ingredients in the tablet.
• Patients with liver or kidney disease should exercise caution and consult a doctor, as dosage adjustments might be necessary.
• Avoid consuming alcohol while taking this medication as it may increase the risk of side effects.
• If you have a history of seizures or epilepsy, use this medication with caution as it may lower the seizure threshold.
• Do not take this medication if you are pregnant or breastfeeding without consulting a healthcare professional.
• Patients with phenylketonuria should be aware that some formulations may contain aspartame, which can be harmful.
• This medication may cause drowsiness or dizziness; avoid driving or operating heavy machinery until you know how it affects you.
• If you have any heart-related conditions, consult your doctor before taking this medication.

Following are the drug interactions for Fexofenadine 120mg and Montelukast 10mg Tablet:

• Erythromycin or ketoconazole may increase the blood levels of Fexofenadine, potentially leading to increased side effects.
• The effectiveness of Montelukast may be reduced by phenobarbital, rifampicin, or phenytoin.
• Grapefruit juice can inhibit the metabolism of Montelukast, resulting in higher drug levels in the body.
• Warfarin's anticoagulant effect may be altered by Fexofenadine, requiring monitoring of coagulation parameters.
• Combining Montelukast with certain anti-epileptic drugs like phenytoin or phenobarbital may affect seizure control.
• The immune response to Fexofenadine may be influenced by concurrent use of immunosuppressants.
• Montelukast can increase the risk of bleeding when taken with antiplatelet drugs or anticoagulants.

Following are the food interactions for Fexofenadine 120mg and Montelukast 10mg Tablet:

• Avoid consuming alcohol with these medications as it may increase the risk of liver-related side effects and affect the metabolism of the drugs.
• Grapefruit and grapefruit juice should be consumed with caution as they can inhibit the CYP3A4 enzyme, potentially increasing the concentration of Montelukast in the blood.
• Fexofenadine absorption can be affected by certain foods, especially fruit juices like apple, orange, and grapefruit juice. It is best to take the medication on an empty stomach with water.
• Dairy products, antacids, and mineral supplements containing aluminum or magnesium can decrease the absorption of Fexofenadine, so avoid taking them together.
• Montelukast can be taken without regard to meals, but a consistent routine is recommended for optimal effectiveness.
• No significant food interactions are known to directly impact the efficacy of these medications.
• Always consult your healthcare provider for personalized advice regarding dietary restrictions and medication interactions.
• Ensure you follow the prescribed dosage and duration of treatment for best results.

Fexofenadine 120mg and Montelukast 10mg tablets should be stored in a cool, dry place, preferably at room temperature between 68°F and 77°F (20°C and 25°C). Keep the tablets in their original container, tightly sealed, to protect them from moisture and light. Avoid storing them in the bathroom or kitchen, as these areas may have excessive heat and humidity. Regularly check the expiration date on the packaging, and do not use the medication if it is past its expiry. When disposing of unused or expired tablets, do not throw them into the trash or flush them down the toilet. Instead, follow local guidelines for medication disposal or consult your pharmacist for safe disposal practices. Keep all medications securely stored, away from children and pets, to prevent accidental consumption.

Following are the quick tips for Fexofenadine 120mg and Montelukast 10mg Tablet:

• Take the medication as directed by your doctor; do not exceed the prescribed dosage.
• Swallow the tablet whole with a full glass of water; do not crush or chew.
• Take Fexofenadine with or without food, but always take Montelukast in the evening with or without food.
• Avoid taking Fexofenadine with fruit juices; separate intake by at least 4 hours.
• Maintain a consistent schedule for better allergy control with Fexofenadine.
• Continue taking Montelukast regularly even if you feel well; it helps manage asthma/allergies.
• Store both medications at room temperature, away from moisture and light.
• Keep all medications out of children's reach.