Fusiderm (250mg) 20 Tablets

Fusidic acid, the active ingredient in Fusidic Acid Tablets, exhibits its antibacterial effect through a unique mechanism of action. It primarily inhibits bacterial protein synthesis by binding to the elongation factor G (EF-G) in susceptible bacteria. EF-G is essential for the translocation step during protein synthesis, where it facilitates the movement of the ribosome along the messenger RNA (mRNA) template. By binding to EF-G, fusidic acid prevents the release of EF-G from the ribosome, thereby blocking the translocation process. This inhibition leads to the disruption of protein synthesis, ultimately inhibiting bacterial growth and replication. Fusidic acid's selective binding to EF-G in bacteria, which is structurally different from the corresponding factor in mammalian cells, contributes to its antibacterial specificity and minimal impact on human protein synthesis.

Fusidic Acid

Antibiotic

Tablet

The following are the uses of Fusidic Acid Tablet:

• Used for treating bacterial skin infections such as impetigo and infected eczema.
• Used for controlling the spread of MRSA (Methicillin-resistant Staphylococcus aureus) infections.
• Used for treating chronic bone infections (osteomyelitis) and joint infections (septic arthritis).
• Used for managing skin ulcers and wounds with bacterial infections.
• Used for respiratory tract infections like severe sinusitis and pneumonia.
• Used for preventing infection in burns and surgical wounds.
• Used for treating severe acne and rosacea when other treatments are ineffective.

To be used as pe doctor's prescription

In the case of an overdose of Fusidic Acid Tablets, it is important to recognize the signs and symptoms, which may include gastrointestinal issues such as nausea, vomiting, and diarrhea. Additionally, there could be an increased risk of skin reactions, such as rashes or hives. If an overdose is suspected, seek medical advice promptly. Quick action can ensure appropriate treatment and minimize potential adverse effects, making timely medical intervention crucial.

In the case of a missed dose of Fusidic Acid Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, consult your healthcare professional for advice on how to proceed, as they may recommend adjusting your dosage or provide specific instructions for catching up on missed doses safely.

To take Fusidic Acid Tablets, swallow the tablet whole with a full glass of water, ensuring you follow the prescribed dosage and schedule provided by your healthcare professional; typically taken every 8 hours for a specified duration.

Following are the conditions/situations when Fusidic Acid Tablet should not be used:

• Avoid in individuals with a known allergy or hypersensitivity to Fusidic Acid or other ingredients in the formulation.
• Not suitable for patients with severe liver impairment or active liver disease.
• Contraindicated in patients with a history of gastrointestinal disorders such as inflammatory bowel disease (IBD) or ulcerative colitis.
• Should not be used if the patient is taking other medications that may interact adversely with Fusidic Acid.
• Not recommended for individuals with a history of kidney disease or significantly impaired kidney function.
• Avoid in patients with a history of severe skin reactions to antibiotics.
• Fusidic Acid is not to be used for the treatment of viral infections such as the common cold or flu.

The side effects of Fusidic Acid Tablet may include:

• Nausea and vomiting.
• Diarrhea.
• Abdominal pain.
• Skin rashes or itching.
• Dizziness or lightheadedness.
• Headache.
• Altered taste sensation.
• Allergic reactions, including swelling of the face, lips, or tongue.

Following are the precautions and warnings for Fusidic Acid Tablet:

• This medication is intended for external use only and should not be swallowed or ingested.
• Do not use Fusidic Acid Tablet if you are allergic to fusidic acid or any other ingredients in the formulation.
• Avoid contact with eyes and mucous membranes; if accidental contact occurs, rinse thoroughly with water.
• Exercise caution if you have a history of liver or kidney disease, as these conditions may require dosage adjustments.
• Prolonged use of Fusidic Acid Tablet may lead to the development of bacterial resistance.
• Discontinue use and seek medical advice if symptoms persist or worsen after a few days of treatment.
• Fusidic Acid Tablet may cause skin irritation or allergic reactions in some individuals; discontinue use if this occurs.
• Keep out of reach of children and pets; store in a cool, dry place away from direct sunlight.

Following are the drug interactions for Fusidic Acid Tablet:

• Fusidic Acid may reduce the effectiveness of hormonal contraceptives, including birth control pills, patches, or vaginal rings, and alternative contraception methods are recommended during treatment.
• It can increase the risk of bleeding when taken with anticoagulants like warfarin, and close monitoring of coagulation parameters is necessary.
• Fusidic Acid may interact with certain antidiabetic medications, potentially affecting blood sugar control, and glucose levels should be monitored closely.
• Concomitant use with ciclosporin can increase ciclosporin levels, requiring dosage adjustments and monitoring.
• Caution is advised when combining with other medications metabolized by the liver, as Fusidic Acid may alter their metabolism, leading to increased side effects.
• Fusidic Acid may decrease the effectiveness of live vaccines, so vaccinations should be scheduled before or after treatment if possible.
• The use of Fusidic Acid with other antibiotics like rifampicin can reduce Fusidic Acid levels, potentially compromising its efficacy.

Following are the food interactions to be aware of when taking Fusidic Acid Tablets:

• Avoid consuming high-fat meals while taking this medication as it may decrease the absorption of Fusidic Acid, reducing its effectiveness.
• Grapefruit and grapefruit juice should be avoided as they can interfere with the metabolism of Fusidic Acid, potentially leading to increased drug levels in the body and a higher risk of side effects.
• Alcohol consumption is generally not recommended during treatment with Fusidic Acid as it may increase the risk of gastrointestinal side effects and liver-related issues.
• Dairy products like milk, cheese, and yogurt may reduce the absorption of Fusidic Acid, so it's best to take the medication at least 2 hours before or after consuming these foods.
• Avoid excessive consumption of caffeinated beverages like coffee and energy drinks as they may increase the metabolism of Fusidic Acid, potentially reducing its effectiveness.
• Leafy green vegetables and foods rich in vitamin K should be consumed in moderation as Fusidic Acid can interfere with vitamin K absorption, affecting blood clotting.
• Maintain a balanced diet and ensure adequate hydration to support overall health and the effectiveness of the medication.
• Always follow the advice of your healthcare provider regarding dietary considerations while taking Fusidic Acid Tablets.

Fusidic Acid Tablets should be stored in a cool and dry place, preferably in their original container, away from direct sunlight, moisture, and heat. It is crucial to maintain a stable room temperature to preserve the integrity of the medication. Always check the expiration date before using any medication, and properly dispose of any unused or expired tablets. Avoid flushing them down the toilet or pouring them into drainage systems. Consult your pharmacist or local waste disposal company for guidance on safe disposal practices. Keep the medication securely stored and out of the reach of children to prevent accidental consumption.

No

Following are the quick tips for Fusidic Acid Tablet:

• Take the tablet as directed by your doctor, typically with or after food.
• Ensure you complete the full course of medication, even if symptoms improve.
• Avoid alcohol consumption during treatment, as it may reduce the effectiveness of the medicine.
• Do not crush or chew the tablet; swallow it whole with water.
• If you experience stomach discomfort, taking the tablet with food can help.
• Store the tablets in a cool, dry place, away from direct sunlight.
• Consult your doctor if you have any concerns or experience persistent side effects.