Fusigel (1.0%) 5g Eye Drops

Fusidic acid, the active ingredient in Fusidic Acid Drops, primarily exerts its antibacterial effect by inhibiting bacterial protein synthesis. It specifically targets a cellular process called translocation during protein synthesis. Fusidic acid binds to the 50S subunit of the bacterial ribosome, preventing the movement of transfer RNA (tRNA) and messenger RNA (mRNA) through the ribosome. This binding action inhibits the elongation step of protein synthesis, thereby disrupting the bacteria's ability to produce essential proteins necessary for their growth and survival. By selectively blocking this vital process, fusidic acid effectively halts bacterial replication and exerts its therapeutic effect.

Fusidic Acid

Antibacterial

Drop

The following are the uses of Fusidic Acid Drop:

• Used for treating bacterial skin infections, such as impetigo, cellulitis, and folliculitis.
• Used for controlling the spread of infection in cases of staphylococcal skin infections.
• Used for reducing symptoms like redness, swelling, and pain associated with bacterial skin issues.
• Used for preventing the growth of certain bacteria on the skin.
• Used for managing recurrent skin infections in individuals with a history of such infections.
• Used for maintaining skin hygiene and preventing secondary infections.
• Used for adjunct therapy alongside other treatments for skin conditions.

In the case of an overdose of Fusidic Acid Drops, it is important to recognize the potential symptoms and take appropriate action. Excessive use may lead to gastrointestinal issues, skin reactions, or other adverse effects. If you suspect an overdose, promptly contact a healthcare professional or a poison control center for guidance. They will provide specific instructions based on the individual's condition and the amount ingested.

In the case of a missed dose of Fusidic Acid Drops, it is important to administer the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to proceed, as they may provide specific instructions based on your individual circumstances.

To use Fusidic Acid Drops, gently tilt your head back, instill the prescribed number of drops into the affected ear(s) as directed by your healthcare provider, and keep your head tilted for a few minutes to allow the medication to penetrate the ear canal.

Following are the conditions/situations when Fusidic Acid Drops should not be used:

• Avoid using if you have a known allergy or sensitivity to Fusidic Acid or any other ingredients in the eye drop formulation.
• Do not use if you have a viral infection in your eye(s), as Fusidic Acid is not effective against viral infections.
• Not recommended for individuals with a history of severe reactions to antibiotics, especially Fusidic Acid or similar medications.
• Contraindicated for patients with undiagnosed red or swollen eyes, as the underlying cause may require different treatment.
• Should not be used if you have a fungal eye infection.
• Avoid using Fusidic Acid drops if you have a history of eye conditions such as glaucoma, unless advised by an ophthalmologist.
• Not suitable for individuals with a history of severe respiratory allergies or asthma triggered by medications.

The side effects of Fusidic Acid Eye Drops may include:

• Eye irritation or redness
• Stinging or burning sensation in the eye
• Watery eyes
• Blurred vision
• Eye itching or discomfort
• Increased sensitivity to light
• Allergic reactions, such as skin rash or itching

Following are the precautions and warnings for Fusidic Acid Drops:

• Do not use Fusidic Acid Drops if you are allergic to fusidic acid or any other ingredients in the formulation.
• Avoid contact with eyes and mucous membranes; if contact occurs, rinse thoroughly with water.
• This medication is intended for external use only; do not ingest or insert into the body.
• Prolonged use of Fusidic Acid Drops may lead to the development of resistant bacteria; use only as directed by your healthcare professional.
• Do not use the drops if the solution changes color or becomes cloudy; discard any remaining solution.
• If symptoms persist or worsen, discontinue use and consult a doctor.
• Keep out of reach of children; store in a cool, dry place away from direct sunlight.

Following are the drug interactions for Fusidic Acid Drop:

• Fusidic Acid may reduce the effectiveness of hormonal contraceptives, so alternative methods of contraception are recommended during treatment.
• Increased risk of bleeding when used with anticoagulants like warfarin, requiring close monitoring of blood clotting parameters.
• The risk of kidney damage is higher when combined with other nephrotoxic drugs, such as certain antibiotics and nonsteroidal anti-inflammatory drugs (NSAIDs).
• Fusidic Acid can interact with drugs metabolized by the liver, potentially increasing blood levels of medications like cyclosporine or certain antiepileptic drugs.
• May decrease the effectiveness of live vaccines, so vaccinations should be administered with caution during and shortly after treatment.
• Alcohol use should be avoided as it may increase the risk of liver-related side effects.
• Certain medications affecting the immune system, such as immunosuppressants, may have altered effects when used concurrently with Fusidic Acid.

Following are the food interactions for Fusidic Acid Drops:

• Avoid consuming grapefruit and grapefruit juice as they may reduce the absorption of Fusidic Acid, leading to decreased effectiveness of the medication.
• Alcohol consumption should be avoided as it can increase the risk of gastrointestinal side effects like nausea and stomach discomfort.
• High-fat meals can slow down the absorption of Fusidic Acid, potentially affecting its overall effectiveness.
• Dairy products like milk and yogurt may interfere with the absorption of Fusidic Acid, so it's best to separate them by a few hours.
• Avoid spicy foods as they can irritate the throat and esophagus, especially if you are experiencing throat soreness or discomfort.
• Caffeinated beverages might increase the acidity in the stomach, potentially causing interactions with Fusidic Acid.
• Certain acidic foods like citrus fruits and tomatoes may cause a burning sensation in the mouth or throat when used with Fusidic Acid Drops.
• It is generally recommended to maintain a balanced diet and stay well-hydrated to support the overall healing process.

Fusidic Acid Drops should be stored in a cool, dry place, preferably between 68°F and 77°F (20°C and 25°C). Protect the bottle from direct sunlight and moisture by keeping it in its original packaging. Ensure the bottle is tightly sealed after each use to maintain its integrity and prevent contamination. When disposing of unused or expired Fusidic Acid Drops, do not pour them down the sink or flush them into the toilet. Contact your pharmacist or healthcare professional for advice on proper disposal methods. Keep the medication away from children and pets to prevent accidental ingestion, as it is intended for external use only. Always exercise caution when handling and storing medications to maintain their effectiveness and safety.

Following are the quick tips for Fusidic Acid Drop:

• Wash your hands before and after applying the drops to maintain hygiene.
• Clean the affected area and ensure it is dry before drop application.
• Apply the prescribed number of drops directly onto the affected skin area.
• Gently rub the drops into the skin until absorbed, avoiding contact with eyes.
• Use the drops as directed by your doctor for the full prescribed duration.
• Do not share your medication with others, even if they have similar symptoms.
• Store Fusidic Acid Drops at room temperature, away from direct sunlight and moisture.