Futine (40mg) 10 Tablets

Fluoxetine hydrochloride 40mg tablets primarily exert their therapeutic effects by selectively inhibiting the reuptake of serotonin (5-hydroxytryptamine or 5-HT) in the brain. Serotonin is a neurotransmitter involved in regulating mood, emotions, and various physiological processes. The mechanism of action involves fluoxetine binding to the serotonin transporter (SERT) protein, which is responsible for the reuptake of serotonin from the synaptic cleft back into the presynaptic neuron. By blocking the reuptake of serotonin, fluoxetine increases the availability of serotonin in the synaptic cleft, allowing for enhanced serotonin signaling. This elevation in serotonin levels is believed to contribute to the antidepressant, anxiolytic, and other therapeutic effects observed with fluoxetine treatment. Fluoxetine's selective action on serotonin reuptake helps restore the balance of this neurotransmitter in the brain, leading to improvements in mood, emotional regulation, and overall well-being in individuals with conditions such as major depressive disorder, obsessive-compulsive disorder, and certain eating disorders.

Fluoxetine Hydrochloride 40mg

Antidepressant, SSRI (Selective Serotonin Reuptake Inhibitor)

Tablet

The following are the uses of Fluoxetine Hydrochloride 40mg Tablet:

• Used for treating depression and helping to improve mood, energy levels, and overall well-being.
• Used for managing obsessive-compulsive disorder (OCD) symptoms, reducing intrusive thoughts and compulsive behaviors.
• Used for addressing panic disorder, decreasing panic attacks and anxiety symptoms.
• Used for treating bulimia nervosa, helping to reduce binge-eating and purging behaviors.
• Used for managing premenstrual dysphoric disorder (PMDD) symptoms, alleviating mood swings, irritability, and physical discomfort.
• Used for certain eating disorders, such as anorexia nervosa, to assist in weight restoration and normalize eating patterns.
• Used for specific anxiety disorders, aiding in controlling excessive worry and associated physical symptoms.
• Used for maintaining recovery and preventing relapse in individuals with major depressive disorder.

In the case of an overdose of Fluoxetine Hydrochloride 40mg Tablets, individuals may experience a range of symptoms. These can include nausea, vomiting, seizures, irregular heartbeat, and in severe cases, it may lead to serotonin syndrome, characterized by high body temperature, agitation, and confusion. Prompt medical intervention is necessary, and healthcare professionals should be contacted immediately to provide appropriate treatment and support to manage the overdose effectively.

In the case of a missed dose of Fluoxetine Hydrochloride 40mg Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is close to the time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication regimen. It is important to maintain consistency with this medication for optimal therapeutic effects.

To take Fluoxetine Hydrochloride 40mg Tablet, swallow the tablet whole with a full glass of water, preferably in the morning or as directed by your healthcare professional, without crushing or chewing.

Following are the conditions or circumstances when Fluoxetine Hydrochloride 40mg Tablet should not be taken:

• Fluoxetine Hydrochloride 40mg Tablet should not be taken by individuals with a known or suspected allergy to Fluoxetine or other selective serotonin reuptake inhibitors (SSRIs).
• Contraindicated in patients who are taking monoamine oxidase inhibitors (MAOIs) or have taken them within the last 14 days, as this can lead to serious drug interactions.
• Should not be used in patients with a history of glaucoma or narrow-angle closure.
• Not recommended for individuals with a history of seizures or epilepsy, as it may lower the seizure threshold.
• Avoid using this medication in patients with severe kidney or liver impairment, as Fluoxetine may need dosage adjustments in these cases.
• Contraindicated in patients with a history of bleeding disorders or those taking anticoagulant medications.
• Should not be used to treat children and adolescents under 18 years of age, unless recommended by a healthcare professional.
• Do not use in patients with a history of heart diseases or congenital heart defects.

The side effects of Fluoxetine Hydrochloride 40mg Tablet may include:

• Nausea and vomiting
• Diarrhea or constipation
• Loss of appetite
• Insomnia (difficulty sleeping)
• Drowsiness or fatigue
• Headaches
• Anxiety or nervousness
• Sexual dysfunction, including decreased libido or difficulty reaching orgasm

Following are the precautions and warnings for Fluoxetine Hydrochloride 40mg Tablet:

• Not suitable for individuals with a known allergy to Fluoxetine or related antidepressants; an alternative medication should be considered.
• Patients with a history of liver or kidney disease should be closely monitored, as Fluoxetine may need dosage adjustments in these cases.
• Avoid alcohol consumption while taking this medication, as it can increase the risk of side effects.
• May cause drowsiness; patients should avoid driving or operating heavy machinery until they know how this medication affects them.
• Not recommended for use in children and adolescents under 18 years old unless advised by a healthcare professional.
• Elderly patients may be more sensitive to the side effects; regular monitoring is essential.
• Consult a doctor immediately if suicidal thoughts or behavior arise, as this medication may increase these risks in some patients.
• Women who are pregnant or breastfeeding should discuss the potential risks and benefits with their healthcare provider before taking Fluoxetine.

Following are the drug interactions for Fluoxetine Hydrochloride 40mg Tablet:

• Interaction with other serotonin-enhancing drugs (e.g., SSRIs, tricyclic antidepressants, MAOIs) can lead to serotonin syndrome, a potentially fatal condition.
• Avoid concurrent use with Monoamine Oxidase Inhibitors (MAOIs), as it may cause serotonin toxicity.
• May increase the effects of anticoagulants like warfarin, requiring close monitoring of INR values.
• Sedation and respiratory depression may be potentiated when used with CNS depressants like opioids or benzodiazepines.
• The risk of bleeding may increase when taken with Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).
• Fluoxetine may elevate plasma levels of drugs metabolized by CYP2D6, such as tricyclic antidepressants, antipsychotics, and beta-blockers.
• Drugs that affect liver enzymes, particularly CYP2D6 inhibitors, may increase Fluoxetine levels, requiring dose adjustments.

Following are the food interactions for Fluoxetine Hydrochloride 40mg Tablet:

• Avoid consuming alcohol during Fluoxetine therapy, as it can increase the risk of side effects and may lead to excessive drowsiness and sedation.
• Grapefruit and grapefruit juice should be consumed with caution as they may increase Fluoxetine levels in the blood, potentially causing higher side effects.
• High-fat meals may delay the absorption of Fluoxetine, leading to a potential decrease in its effectiveness.
• Caffeine-containing beverages like coffee, tea, and energy drinks should be limited as they can increase anxiety and restlessness, counteracting the therapeutic effects of Fluoxetine.
• Avoid aged or fermented foods containing tyramine, such as aged cheeses, cured meats, and certain types of beer, as they may interact with Fluoxetine, potentially leading to increased blood pressure.
• Maintain a balanced diet; some individuals may experience weight changes while on Fluoxetine, so monitoring calorie intake is advisable.
• Always follow your healthcare provider's dietary recommendations, especially if you have specific dietary restrictions or health conditions.
• Fluoxetine may cause a slight decrease in appetite, so ensuring adequate nutrition is essential to prevent nutritional deficiencies.

Fluoxetine Hydrochloride 40mg Tablets should be stored in a secure and dry location, preferably in a medicine cabinet or a designated storage area, away from direct sunlight and moisture. It is crucial to keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent exposure to external elements. Avoid storing them in the bathroom or kitchen, as these areas can have temperature fluctuations that may impact the medication. Always check the expiration date, and if the tablets have passed their expiry, it is important to dispose of them responsibly. Proper disposal methods should be followed, such as returning the medication to a pharmacy or a designated collection point for safe disposal. Keep the medication out of children's reach to ensure their safety and prevent accidental consumption.

Following are the quick tips for Fluoxetine Hydrochloride 40mg Tablet:

• Consult your doctor for the right dosage and duration tailored to your condition.
• Take the tablet as a whole; do not crush, chew, or break it.
• Maintain a consistent daily routine for taking the medication.
• Swallow the tablet with a full glass of water for easier swallowing.
• Avoid missing doses; take it as soon as you remember, but skip if it's almost time for the next dose.
• Inform your doctor about all medications you're taking to prevent potential drug interactions.
• Store the medication at room temperature, away from moisture and light.