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Gabfast (75mg) 14 Capsules

Gabfast (75mg) 14 Capsules

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  • Manufacturer Danas Pharmaceuticals (Pvt.) Ltd.

Product Information

  • Description

    Pregabalin, a CNS-active drug with anti-epileptic, anticonvulsant, and anti-nociceptive (pain inhibitory) effects. Pregabalin is chemically designated as (S)-3-(amino methyl)-5-methylhexanoic acid. Pregabalin exerts its effects by binding to the α2δ subunit of voltage-dependent calcium channels, after binding; pregabalin modulates the release of several excitatory neurotransmitters including glutamate, substance-P, norepinephrine, and calcitonin gene related peptide. Pregabalin also prevents the alpha2-delta subunit from being trafficked from the dorsal root ganglia to the spinal dorsal horn, which may also contribute to the mechanism of action. It is effective in management of neuropathic pain associated with diabetic peripheral neuropathy, post herpetic neuralgia, Adjunctive therapy for adult patients with partial onset seizures(with or without secondary generalization), fibromyalgia, pain associated with spinal cord injury, generalized anxiety disorder in adults.
  • Dosage Form

  • Uses

    Management of Neuropathic pain associated with diabetic peripheral Neuropathy, post herpetic Neuralgia, Adjunctive therapy for adult patients with Partial onset Seizures (with or without secondary generalization), Fibromyalgia, pain associated with spinal cord injury, Generalized Anxiety Disorder (GAD) in adults.
  • Dosage

    Starting dose for all indications is 150 mg/day given as 2 or 3 divided doses. Dose may be increased to 300 mg/day within a period one week.
  • In case of Overdose

    Consult your doctor in case of overdose. Overdose may cause; somnolence, confusion, agitation, and restlessness. There is no specific antidote for overdose with Pregabalin. If indicated, elimination of unabsorbed drugs may be attempted by emesis or gastric lavage; observe usual precautions to maintain the airway. General supportive care of the patient is indicated including monitoring of vital signs and observation of the clinical status of the patient. Although hemodialysis has not been performed in the few known cases of overdose, it may be indicated by the patient's clinical state or in patients with significant renal impairment. Standard hemodialysis procedures result in significant clearance of pregabalin (approximately 50% in 4 hours).
  • Missed Dose

    In case you missed any dose, take the next dose as soon as you remember, but don't double your next dose to compensate for the missed one.
  • How To Use

    Use orally, as advised by the physician.
  • When Not to Use

    This medicine is contraindicated in patients with known hypersensitivity to pregabalin.
  • Side Effects

    Dizziness Somnolence Angioedema Allergic reaction Metabolism Nutrition Disorders Appetite increased Anorexia Hypoglycemia
  • Precautions & Warnings

    Angioedema and hypersensitivity reactions have occurred in patients receiving pregabalin therapy.
  • Storage/Disposal

    Store below 25°C, at a dry place.

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