Gamalate B6 60 Tablets

Gamalate B6 60 Tablets

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  • Manufacturer ALINA COMBINE PAKISTANLTD
  • Generic Name

    Gamma-Amino Beta-Hydroxybutyric Acid, Gamma-Aminobutyric Acid, Magnesium Glutamate, Pyridoxine HCL

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    Gamma-Amino Beta-Hydroxybutyric Acid (GABOB) is a structural analogue of the neurotransmitter Gamma-Aminobutyric Acid (GABA) and binds to GABA receptors, particularly the GABAB receptors, which leads to an increase in chloride ion conductance, hyperpolarization of the cell membrane, and inhibition of neuronal activity. GABA, the primary inhibitory neurotransmitter in the central nervous system, binds to both GABAA and GABAB receptors, enhancing chloride conductance and hyperpolarizing neurons, thereby reducing neuronal excitability. Magnesium Glutamate acts as a cofactor for various enzymes involved in neurotransmitter synthesis and metabolism, and it can modulate NMDA receptor activity, influencing glutamate-mediated neurotransmission. Pyridoxine HCL, a form of vitamin B6, is a cofactor for enzymes involved in GABA synthesis, enhancing the conversion of glutamate to GABA, thereby increasing GABA levels in the brain. Together, these components synergistically promote inhibitory neurotransmission, potentially leading to a calming effect on the central nervous system.

  • Ingredients

    Gamma-Amino Beta-Hydroxybutyric Acid, Gamma-Aminobutyric Acid, Magnesium Glutamate, Pyridoxine HCL

  • Drug Class

    Nutritional Supplement

  • Dosage Form

    Tablet

  • Uses

    The following are the uses of Gamma-Amino Beta-Hydroxybutyric Acid, Gamma-Aminobutyric Acid, Magnesium Glutamate, Pyridoxine HCL Tablet:

    • Used for promoting muscle relaxation and reducing stress and anxiety.
    • Used for enhancing mood and supporting a calm, focused state of mind.
    • Used for improving sleep quality and aiding in relaxation before bedtime.
    • Used for supporting cognitive function and mental clarity.
    • Used for managing muscle spasms and promoting muscle recovery.
    • Used for reducing symptoms of premenstrual syndrome (PMS) and supporting hormonal balance.
    • Used for enhancing exercise performance and aiding in post-workout recovery.
    • Used for supporting overall nervous system health and function.
  • In case of Overdose

    In the case of an overdose of Gamma-Amino Beta-Hydroxybutyric Acid, Gamma-Aminobutyric Acid, Magnesium Glutamate, or Pyridoxine HCL Tablet, the symptoms may include severe drowsiness, confusion, and respiratory depression. Immediate medical attention is required, as prompt intervention can prevent potential life-threatening complications. Treatment involves supportive care, monitoring vital signs, and managing respiratory distress to ensure the patient's safety and well-being.

  • Missed Dose

    In the case of a missed dose of Gamma-Amino Beta-Hydroxybutyric Acid, Gamma-Aminobutyric Acid, Magnesium Glutamate, or Pyridoxine HCL Tablet, it is generally recommended to take the missed dose as soon as you remember, provided it is not too close to the time of your next scheduled dose. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects.

  • How To Use

    To take the Gamma-Amino Beta-Hydroxybutyric Acid, Gamma-Aminobutyric Acid, Magnesium Glutamate, Pyridoxine HCL Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional.

  • When Not to Use

    Following are the conditions or situations when Gamma-Amino Beta-Hydroxybutyric Acid, Gamma-Aminobutyric Acid, Magnesium Glutamate, and Pyridoxine HCL Tablet should not be used:

    • Should not be taken by individuals with a known allergy or sensitivity to any of the active ingredients or excipients in the formulation.
    • Contraindicated in patients with a history of severe adverse reactions to any component of the supplement.
    • Not suitable for individuals with kidney disease or impaired kidney function.
    • Should not be used in individuals with a history of seizures or epilepsy.
    • Not recommended for individuals with bipolar disorder or those taking antidepressant medications.
    • Contraindicated in patients with liver disease or severe liver impairment.
    • Should be avoided during pregnancy and breastfeeding, unless specifically advised by a healthcare professional.
    • Not suitable for children and adolescents under the age of 18 years.
    • Should not be used in patients with a history of gastrointestinal bleeding or obstruction.
    • Avoid using if you have a scheduled surgery or recently had surgery.
  • Side Effects

    The side effects of Gamma-Amino Beta-Hydroxybutyric Acid, Gamma-Aminobutyric Acid, Magnesium Glutamate, Pyridoxine HCL Tablet may include:

    • Drowsiness or sedation
    • Muscle weakness or relaxation
    • Dizziness or lightheadedness
    • Confusion or disorientation
    • Nausea and vomiting
    • Dry mouth
    • Changes in heart rate or blood pressure
    • Allergic reactions (skin rash, itching, swelling)
  • Precautions & Warnings

    Following are the precautions and warnings for Gamma-Amino Beta-Hydroxybutyric Acid, Gamma-Aminobutyric Acid, Magnesium Glutamate, Pyridoxine HCL Tablet:

    • This medication should be used with caution in patients with a history of liver or kidney disease, as it may require dosage adjustments under medical supervision.
    • Not suitable for individuals with a known allergy to any of its components, and immediate medical attention should be sought if an allergic reaction occurs.
    • May cause drowsiness or dizziness, so patients should avoid driving or operating heavy machinery until they know how this medication affects them.
    • Alcohol consumption should be avoided or limited while taking this medication, as it may intensify side effects.
    • Pregnant or breastfeeding women should consult their doctor before use, as the potential risks may outweigh the benefits.
    • Keep out of reach of children. Store in a cool, dry place, away from direct sunlight.
    • Discontinue use and contact a healthcare professional if any adverse reactions or symptoms persist or worsen.
  • Drug Interactions

    Following are the drug interactions for Gamma-Amino Beta-Hydroxybutyric Acid, Gamma-Aminobutyric Acid, Magnesium Glutamate, and Pyridoxine HCL Tablet:

    • May interact with other central nervous system depressants like benzodiazepines or alcohol, leading to enhanced sedation and impaired motor skills.
    • Pyridoxine (vitamin B6) in high doses may reduce the effectiveness of certain anti-epileptic medications, such as phenytoin and phenobarbital.
    • Gamma-aminobutyric acid (GABA) supplements may decrease the absorption of certain medications, including some antibiotics and antifungal drugs.
    • Magnesium supplements can interfere with the absorption of tetracycline antibiotics, reducing their effectiveness.
    • May reduce the efficacy of antihypertensive medications, potentially requiring dosage adjustments.
    • Concomitant use with monoamine oxidase inhibitors (MAOIs) is not recommended due to potential adverse effects on blood pressure.
    • Should be used cautiously with diuretics, as it may increase the risk of electrolyte imbalances.
  • Food Interactions

    Following are the food interactions for Gamma-Amino Beta-Hydroxybutyric Acid, Gamma-Aminobutyric Acid, Magnesium Glutamate, and Pyridoxine HCL Tablet:

    • Avoid excessive consumption of foods rich in glutamate, such as monosodium glutamate (MSG), as it may lead to a condition called 'Chinese Restaurant Syndrome', causing symptoms like headache, flushing, and sweating.
    • Limit the intake of tyramine-rich foods like aged cheeses, cured meats, and certain types of beer, as they can interact with Gamma-Aminobutyric Acid and Pyridoxine, potentially leading to increased blood pressure.
    • Alcohol may enhance the sedative effects of Gamma-Aminobutyric Acid, so it's best to limit or avoid alcohol consumption.
    • Magnesium-rich foods like leafy greens, nuts, and seeds can support the effects of Magnesium Glutamate but excessive intake may lead to diarrhea.
    • Vitamin B6-rich foods like fish, poultry, and whole grains can complement Pyridoxine HCL, but excessive intake may lead to neurological symptoms.
    • Avoid grapefruit and grapefruit juice as they can affect the metabolism of Pyridoxine.
    • Consult a healthcare provider if you have specific dietary concerns or restrictions.
    • Maintain a balanced diet to ensure optimal absorption and effectiveness of these supplements.
  • Storage/Disposal

    Gamma-Amino Beta-Hydroxybutyric Acid, Gamma-Aminobutyric Acid, Magnesium Glutamate, and Pyridoxine HCL Tablets should be stored in a cool, dry area, preferably at room temperature, ensuring protection from light and moisture. It is crucial to store the tablets in their original packaging, tightly sealed, to maintain their integrity. Avoid exposing the medication to heat or freezing temperatures, as this can impact its effectiveness. When disposing of unused or expired tablets, do not flush them or throw them into the trash. Instead, follow local guidelines or consult a healthcare professional for safe disposal methods, ensuring that the medication is kept away from children and pets at all times.

  • Quick Tips, if any

    Following are the quick tips for Gamma-Amino Beta-Hydroxybutyric Acid, Gamma-Aminobutyric Acid, Magnesium Glutamate, and Pyridoxine HCL Tablet:

    • Consult a healthcare professional for personalized advice on dosage and usage.
    • Ensure you understand the recommended dosage and duration of use.
    • Take these supplements with a full glass of water for better absorption.
    • Maintain a consistent daily routine for taking these supplements.
    • Consider taking them with food if stomach sensitivity occurs.
    • Store in a cool, dry place, away from direct sunlight.
    • Keep out of reach of children and pets.
    • Do not exceed the recommended dosage without medical guidance.

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