GAMIMUNE N 2.5 GRAMS 50ML INJ 5%

Immune Globulin Injection works by providing passive immunity to the recipient. It contains a pool of antibodies (immunoglobulins) derived from the plasma of healthy donors who have high levels of antibodies against various pathogens. When administered, the immunoglobulins in the injection bind to specific antigens, such as viruses or bacteria, neutralizing their effects and preventing them from causing harm. This mechanism helps to enhance the immune response, providing immediate protection against infectious diseases, especially in individuals with compromised immune systems or those lacking specific antibodies. The diverse array of antibodies in the immune globulin injection ensures broad-spectrum coverage against multiple pathogens, making it an effective treatment for various immune-related conditions.

Immune Globulin

Immunological Agent

Injection

The following are the uses of Immune Globulin Injection:

• Used for boosting the immune system to fight various diseases and infections.
• Used for treating immune deficiencies, providing essential antibodies.
• Used for preventing certain infections in individuals with a weak immune system.
• Used for reducing the severity and symptoms of autoimmune disorders.
• Used for treating neurological conditions by modulating immune responses.
• Used for managing inflammatory conditions, offering targeted relief.
• Used for post-exposure prophylaxis, preventing disease after exposure.
• Used for providing passive immunity in emergencies or specific medical scenarios.

In the case of an overdose of Immune Globulin Injection, it is important to seek medical advice promptly. Overdose symptoms may include fluid imbalances, increased blood viscosity, and potential allergic reactions. Adverse effects can be managed by reducing the dosage or temporarily discontinuing the medication. Close monitoring and appropriate medical care are necessary to address any complications that may arise from an overdose.

In the case of a missed dose of Immune Globulin Injection, it is important to administer the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses or have concerns about maintaining a consistent treatment plan, consult your healthcare provider for guidance on how to manage missed doses effectively.

To administer the Immune Globulin Injection, clean the injection site with an alcohol swab, insert the needle at a 90-degree angle, inject the medication slowly, and then gently withdraw the needle, applying pressure with a sterile bandage if needed.

Here are the conditions or situations when Immune Globulin Injection should not be used:

• Do not use if you have a known severe allergy to any ingredient in the immune globulin product.
• Contraindicated in individuals with a history of severe systemic reactions to immunoglobulin therapy.
• Should not be administered to individuals with selective immunoglobulin A (IgA) deficiency, as they may have antibodies against IgA.
• Not recommended for patients with severe thrombocytopenia or a history of thrombotic events.
• Avoid in individuals with severe kidney disease or impaired renal function.
• Do not use if you have severe anemia or other blood disorders.
• Contraindicated in patients with a history of anaphylactic or severe systemic reactions to blood or plasma products.
• Should not be used in individuals with severe infections or active diseases such as tuberculosis.
• Not suitable for patients with severe heart disease or a history of myocardial infarction.

The side effects of Immune Globulin Injection may include:

• Headache
• Fatigue and dizziness
• Nausea and vomiting
• Muscle pain and joint aches
• Skin reactions such as rash or itching
• Fever or chills
• Increased blood pressure
• Rare cases of allergic reactions.

Following are the precautions and warnings for Immune Globulin Injection:

• Patients with a history of allergic reactions to blood products or immunoglobulins should be carefully monitored as they may be at a higher risk of adverse reactions.
• Ensure that the patient is not volume-depleted before administering the injection, as it may lead to pulmonary edema or acute renal failure.
• Immune Globulin should be administered with caution to patients with pre-existing renal insufficiency, as it may further impair renal function.
• Patients with a history of thrombosis or cardiovascular risk factors should be assessed for potential risks, as it may increase the risk of thromboembolic events.
• Elderly patients may be more susceptible to adverse reactions, especially renal dysfunction and thromboembolic events.
• Patients with a history of immunoglobulin A (IgA) deficiency and antibodies to IgA should not receive this medication to avoid anaphylactic reactions.
• The product should be inspected for particulate matter and discoloration before administration, and should not be used if any abnormalities are found.
• Immune Globulin should be administered under the supervision of a healthcare professional, and patients should be monitored for any immediate adverse reactions during and after the infusion.

Following are the drug interactions for Immune Globulin Injection:

• Concomitant use may result in reduced vaccine efficacy due to antibody formation.
• May interfere with the desired effect of Immune Globulin, as it suppresses the immune response.
• Can increase the risk of bleeding, as Immune Globulin may enhance the anticoagulant effect.
• May increase the risk of anaphylaxis, especially in patients with IgA deficiency.
• Concurrent use can increase the risk of renal impairment, as Immune Globulin is eliminated by the kidneys.
• Should not be mixed with other drugs due to potential interactions and compatibility issues.
• Interactions may occur with drugs that modulate the immune response, requiring close monitoring.

Following are the food interactions for Immune Globulin Injection:

• Avoid live or live-attenuated vaccines as Immune Globulin can interfere with their effectiveness, reducing the body's immune response to these vaccines.
• There is no specific food restriction, but maintaining a balanced diet is essential to support overall health and immune function.
• Ensure adequate hydration before and after the injection to aid in the distribution of the medication and reduce the risk of side effects.
• Avoid high-fat meals as they may slow down the absorption of injected medications, although this may not be a significant concern with Immune Globulin specifically.
• Alcohol consumption should be limited as it may impact the immune system and potentially interfere with the medication's effectiveness.
• Grapefruit and grapefruit juice are generally safe but consult your healthcare provider as they can interact with certain medications, although this is not a common concern with Immune Globulin.
• No known food interactions directly affect the absorption or metabolism of Immune Globulin, but individual responses may vary.
• Always follow healthcare provider's instructions for any dietary considerations related to Immune Globulin Injection.

Storage and disposal of Immune Globulin Injection require specific attention to maintain its integrity and ensure safety. Store the injection at room temperature, away from direct sunlight and heat sources, as extreme temperatures can impact its effectiveness. Keep the injection in its original packaging, tightly sealed, to prevent contamination and maintain sterility. Always check the expiration date before use and discard any expired or unused vials promptly. For disposal, do not flush or pour the injection down the drain; instead, contact your healthcare provider or pharmacist for guidance on proper disposal methods, as they can provide environmentally friendly and safe options. Keep the medication out of children's reach to prevent accidental exposure.

Following are the quick tips for Immune Globulin Injection:

• Ensure the injection is administered by a healthcare professional for safety.
• Verify the prescribed dosage and injection site to prevent errors.
• Remain seated or lying down during the injection for stability.
• Relax the muscle at the injection site to ease the process.
• Inform your doctor about any allergies or medications to prevent adverse reactions.
• After the injection, apply pressure to the site and monitor for any swelling or bruising.
• Store the injection as directed and keep it out of children's reach.
• Report any persistent side effects or injection site reactions to your healthcare provider.