GASTROPLANT 20ML (WS)

The mechanism of action of GASTROPLANT 20 Liquid primarily involves the active ingredient sucralfate, which is a cytoprotective agent. Sucralfate forms a protective complex with proteins and binds to the ulcer crater, creating a barrier over the damaged mucosa. This barrier is resistant to digestion by stomach acid and enzymes, allowing the underlying tissue to heal. It also stimulates the production of mucus and bicarbonate, which helps neutralize stomach acid and provides additional protection to the gastrointestinal lining. By forming this protective layer and promoting a more favorable pH environment, sucralfate aids in the healing of gastric and duodenal ulcers and provides relief from associated symptoms.

Antacid/antifoaming complex.

Liquid

The following are the uses of GASTROPLANT 20 Liquid:

• Used for relieving heartburn and acid reflux symptoms
• Used to treat stomach ulcers and inflammation
• Used in managing gastroesophageal reflux disease (GERD)
• Used to reduce stomach acid production
• Used for soothing the esophagus and stomach lining
• Used to aid in healing and preventing further damage
• Used as a short-term treatment for upper gastrointestinal issues
• Used to provide temporary relief from gastrointestinal discomfort

In the case of an overdose of GASTROPLANT 20 Liquid, the severity of symptoms can vary. Common effects may include increased drowsiness, confusion, and dizziness. In more severe cases, individuals might experience difficulty breathing, loss of consciousness, or even seizures. It is crucial to promptly seek medical assistance and provide healthcare professionals with information about the amount ingested, as this will enable them to offer the most appropriate treatment and support.

In the case of a missed dose of GASTROPLANT 20 Liquid, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. If you miss multiple doses, contact your healthcare professional for advice on how to get back on track with your medication regimen. It's important to maintain consistency with this medication for optimal therapeutic effects.

To take GASTROPLANT 20 Liquid, shake the bottle, measure the prescribed dose with a measuring device, and consume it orally once daily, following the dosage instructions provided by your healthcare professional, regardless of meals.

Here are the conditions and situations when GASTROPLANT 20 Liquid should not be used:

• Do not use if you are allergic to any of the ingredients in the liquid formulation.
• Contraindicated in individuals with a known hypersensitivity or severe reaction to peppermint oil, caraway oil, or any other similar herbal oils.
• Should not be used if you have a blockage or obstruction in the gastrointestinal tract, including conditions like pyloric stenosis or intestinal obstruction.
• Not suitable for individuals with severe liver disease or impaired liver function.
• Avoid using in patients with severe kidney disease or those on dialysis.
• Do not use in children under 12 years of age unless prescribed by a healthcare professional.
• Contraindicated during pregnancy, especially in the first trimester, unless the potential benefits outweigh the risks.
• Should not be used while breastfeeding as it may pass into breast milk and potentially harm the infant.
• Avoid using if you have a history of severe gastrointestinal disorders, such as gastroesophageal reflux disease (GERD) or peptic ulcers, without consulting a doctor.
• Do not use if you have a history of gallstones or biliary tract disease, as it may worsen these conditions.

The side effects of GASTROPLANT 20 Liquid may include:

• Nausea and vomiting
• Diarrhea or constipation
• Abdominal pain or cramps
• Dry mouth
• Headache or dizziness
• Fatigue and weakness
• Skin rash or itching

Following are the precautions and warnings for GASTROPLANT 20 Liquid:

• Do not use if you are allergic to any of the ingredients in the liquid formulation.
• This medication may cause drowsiness or dizziness, so caution is advised when performing tasks that require mental alertness. Avoid driving or operating machinery if affected.
• It is recommended to consult a doctor if you have a history of liver or kidney disease before taking this medication.
• Alcohol consumption should be avoided as it may increase the risk of side effects.
• Do not exceed the recommended dosage, as it may lead to serious adverse effects.
• Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding before using this medication.
• Keep out of reach of children and pets. Store in a cool, dry place, away from direct sunlight.

Following are the drug interactions for GASTROPLANT 20 Liquid:

• Antacids containing aluminum or magnesium may decrease the absorption of sucralfate, the active ingredient in GASTROPLANT, and should be taken at least 2 hours apart.
• Concomitant use with H2-receptor antagonists (e.g., cimetidine, ranitidine) or proton pump inhibitors (e.g., omeprazole, lansoprazole) may alter the effectiveness of either medication, so separate administration by 2 hours.
• Tetracycline antibiotics should be taken at least 2 hours before or 4 hours after GASTROPLANT to avoid decreased absorption.
• Avoid using GASTROPLANT with other drugs that may cause constipation, such as certain opioids or anticholinergics, as it may worsen this side effect.
• The absorption of certain medications like fluoroquinolone antibiotics and phenytoin may be reduced when taken with GASTROPLANT, requiring dosage adjustments.
• Drugs that increase gastric pH, such as proton pump inhibitors, may increase the risk of Clostridium difficile-associated diarrhea when used with GASTROPLANT.
• GASTROPLANT may interact with medications that are sensitive to pH changes in the stomach, potentially affecting their absorption.

Following are the food interactions for GASTROPLANT 20 Liquid:

• Avoid consuming alcohol with this medication as it may increase the risk of side effects and impair your ability to drive or operate machinery.
• Grapefruit and grapefruit juice should be consumed with caution as they may interfere with the medication's metabolism, leading to increased levels of the drug in the body.
• High-fat meals can potentially slow down the absorption of this medication, so it is advisable to take it on an empty stomach or as directed by your healthcare professional.
• Avoid caffeine-rich foods and beverages as they may increase stomach acid production and potentially reduce the medication's effectiveness.
• Dairy products, especially milk, can interact with the medication's absorption. Consider separating milk consumption from taking this medication by at least 2 hours.
• Avoid excessive consumption of spicy foods as they can irritate the stomach and potentially reduce the medication's efficacy.
• Inform your doctor if you regularly consume large amounts of vitamin C-rich foods, as high doses of vitamin C may interfere with the medication's action.
• Always follow the instructions provided by your healthcare provider regarding specific dietary restrictions or recommendations during the treatment period.

Storage and disposal of GASTROPLANT 20 Liquid require careful attention to ensure its integrity and safety. Store the liquid in a cool, dry area, maintaining room temperature, and shield it from direct sunlight and moisture. Keep the medication securely sealed in its original packaging to prevent contamination. Avoid storage in bathrooms or near heat-emitting appliances, as temperature fluctuations can compromise the medicine's quality. Regularly check the expiration date, and if the liquid is no longer needed or has expired, dispose of it responsibly. Avoid improper disposal methods like flushing or pouring it down the drain; consult a pharmacist or healthcare professional for guidance on safe disposal practices. Lastly, ensure the medication is kept securely away from children to prevent accidental ingestion.

Following are the quick tips for GASTROPLANT 20 Liquid:

• Store the liquid at room temperature, away from direct sunlight and moisture.
• Before use, check the expiration date and ensure the liquid is clear and free from particles.
• Measure the prescribed dose accurately using the provided measuring cup or syringe.
• Administer the liquid directly into the mouth or mix it with a small amount of water or juice if preferred.
• Do not mix with hot beverages as it may affect the medication's properties.
• Avoid missing doses to ensure the best treatment outcome.
• Consult your doctor if you have any concerns or experience persistent side effects.