Glomov (500/20mg) 28 Tablet

Glomov (500/20mg) 28 Tablet

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  • Manufacturer Global Pharmaceuticals (Pvt.) Ltd.
  • Generic Name Naproxen, Esomeprazole

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Rs. 207.96 Rs. 231.07 10% OFF
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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Description

    Naproxen 500mg is a prescription-strength nonsteroidal anti-inflammatory drug (NSAID) commonly used to relieve pain, tenderness, and swelling caused by different types of arthritis. It is also effective for relieving menstrual cramps and various other mild to moderate pains, including muscle strains and backaches. Naproxen works by inhibiting the enzyme cyclooxygenase (COX-1 and COX-2), which helps reduce the production of prostaglandins, the hormones causing pain and inflammation. Esomeprazole 20mg, on the other hand, is a proton pump inhibitor (PPI) used to treat symptoms associated with gastroesophageal reflux disease (GERD), ulcers, and specific stomach conditions. Its mechanism of action involves inhibiting the proton pump enzyme system, reducing the production of stomach acid. By lowering the acid levels in the stomach, esomeprazole helps alleviate symptoms such as heartburn, indigestion, and stomach pain. By blocking the final step of acid production, esomeprazole prevents the stomach from secreting excess acid, leading to relief from acid reflux symptoms and promoting the healing of ulcers and other damage to the stomach and esophagus lining. Together, Naproxen 500mg, and Esomeprazole 20mg provide effective relief from both pain and acidity when combined in a single dosage form. The naproxen reduces pain and inflammation, while the esomeprazole reduces acid secretion, helping to address any accompanying acidity or stomach irritation. This combination is especially beneficial for individuals who experience both pain and acid reflux symptoms, providing comprehensive relief and improved quality of life.

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  • Ingredients

    Naproxen, Esomeprazole
  • Drug Class

    Naproxen Is Nsaid,Esomeprazole Is A Proton Pump Inhibitor.

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  • Dosage Form

    Tablet

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  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Naproxen 500mg is an anti-inflammatory drug that is used to relieve pain, tenderness, and swelling caused by osteoarthritis, rheumatoid arthritis, and other conditions.
    • Esomeprazole 20mg is a proton pump inhibitor that is used to treat stomach ulcers, heartburn, and other conditions.
    • Both drugs are used together for the treatment of stomach pain and inflammation associated with NSAID (non-steroidal anti-inflammatory drug) intake and other conditions.

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  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Naproxen 500mg-
    • Osteoarthritis- 1500-2000mg per day in divided doses
    • Rheumatoid arthritis- 1200-1500mg per day in divided doses
    • Ankylosing spondylitis- 1500-2000mg per day in divided doses
    • Chronic musculoskeletal pain- 1500-2000mg per day in divided doses
    • Primary dysmenorrhea- 1250-1500mg per day in divided doses
    • Postoperative pain- 500-550mg every 6-8 hours with a maximum of 2000mg per day
    • Esomeprazole 20mg-
    • Treatment of heartburn and symptoms of gastroesophageal reflux disease (GERD)- 20-40mg once daily for 4 weeks
    • Prevention of NSAID-associated gastric ulcers- 20mg once daily for 3-6 months
    • Treatment of actively bleeding gastric or duodenal ulcers- 40mg once or twice daily until ulcer healing
    • Treatment of pathological hypersecretory conditions- 40mg once daily
    • Prevention of NSAID-associated gastropathy in patients with critically impaired renal function- 20mg once daily

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  • In case of Overdose

    An overdose of Naproxen 500mg and Esomeprazole 20mg can lead to adverse symptoms and should be treated as a medical emergency. If you suspect someone has overdosed on these medications, it is vital to contact local emergency services or visit the nearest emergency room immediately.

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  • Missed Dose

    If you have missed a dose of your medication, it is important to take it as soon as possible. If it is nearly time for your next dose, skip the missed dose and maintain your regular schedule. Doubling up on medication to make up for a missed dose is not advised. If you have specific questions about your medication, speak with a medical professional for guidance on your personal treatment plan. Further, it is important to adhere to the prescription drug schedule as closely as possible. But if you have missed a dose, it is crucial to consult the prescription drug guide or a certified physician to learn about the best way forward. It is crucial to approach prescription drugs with caution and consult certified medical personal for any questions or concerns.

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  • How To Use

    Naproxen, typically taken as a 500mg tablet or liquid gel capsule, should be taken twice a day, with or without food. When taking Naproxen, it is important to be consistent and take your medication either always with food or always without food. Similarly, to reduce the risk of stomach irritation and ulcers, Naproxen should be taken with a glass of water and alongside a low-dose proton pump inhibitor (PPI) such as Esomeprazole 20mg. To ensure the PPI has taken full effect to reduce the stomach's acidity, it should be taken at least 30 minutes before Naproxen. Esomeprazole 20mg, a proton pump inhibitor (PPI), is typically recommended to be taken once daily, ideally at the same time each day. This medication should be swallowed whole without being crushed or chewed, to ensure the delayed release of the drug. It is important to follow the specific instructions provided by your physician or pharmacist regarding the timing, dosage, and any special considerations when taking these medications. Always consult with your healthcare provider or pharmacist if you have any questions or concerns regarding your medication.

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  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • Naproxen 500mg
    • Had recent surgery or have ongoing bleeding problems.
    • Had a history of ulcers or gastrointestinal bleeding.
    • Heart failure or kidney problems.
    • Chest pain or other heart conditions.
    • Asthma or other breathing problems.
    • Esomeprazole 20mg
    • Allergy to esomeprazole or other proton-pump inhibitors (PPIs).
    • Had liver disease or cirrhosis.
    • Low magnesium levels or chronic kidney disease.
    • Taking an immunosuppressant or antirejection medication.

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  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Stomach pain, nausea, vomiting, heartburn, and upset stomach
    • Diarrhea
    • Constipation
    • Headaches
    • Dizziness
    • Ringing in the ears
    • Difficulty sleeping or insomnia
    • Irritability
    • Fatigue or drowsiness
    • Dependency (with long-term use)
    • Heartburn or acid reflux
    • Ulcers
    • Black tarry stools
    • Vomiting of blood or bloody stools

    Naproxen 500mg

    • Muscle pain
    • Joint pain
    • Headaches
    • Dizziness
    • Nausea
    • Diarrhea
    • Constipation
    • Fatigue
    • Mood swings
    • Impaired wound healing
    • Low magnesium and calcium levels
    • Increased risk of pneumonia

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  • Precautions & Warnings

    The warnings and precautions for Naproxen and Esomeprazole include several important considerations. For Naproxen, there is a risk of gastrointestinal bleeding or ulcers, cardiovascular events, and renal impairment. It is advised to avoid concurrent use with other NSAIDs or anticoagulants, and caution is advised during pregnancy and lactation. Regarding Esomeprazole, it poses a risk of Clostridium difficile-associated diarrhea and may increase the risk of osteoporosis. Additionally, it can mask symptoms of gastric malignancy, and its metabolism can vary due to CYP2C19 variability. Patients with hepatic impairment should be closely monitored, and caution is also advised for use during pregnancy and lactation.

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  • Drug Interactions

    The drug interactions with the naproxen and esomeprazole combination include:

    • Other NSAIDs – May increase the risk of gastrointestinal bleeding and ulceration.
    • Anticoagulants – May enhance the risk of bleeding.
    • CYP2C19 Inhibitors – Can affect esomeprazole metabolism, altering its effectiveness.

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  • Food Interactions

    The food interactions that should be considered while using Glomov are:

    • No significant interactions with food.
    • Taking with food may help improve absorption

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  • Storage/Disposal

    When storing Naproxen 500mg and Esomeprazole 20mg,crucial guidelines should be followed to ensure the medications remain effective. Store at room temperature, away from direct light, moisture, and heat. Keep the capsules in their original packaging and out of reach of children and pets. Do not store in the bathroom. Do not flush down the toilet or pour into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more information on how to safely discard your medication.

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